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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Atopic dermatitis is one of the most common allergic skin diseases in dogs and is caused by allergens such as house dust mites or pollens which stimulate an exaggerated immune response in atopic dogs. The disease is chronic, recurrent and may require lifelong management.
ATOPICA (Cyclosporine) selectively acts on the immune cells involved in the allergic reaction. ATOPICA (Cyclosporine) reduces the inflammation and itching associated with atopic dermatitis.
Canine atopy can be difficult to distinguish from flea allergy dermatitis, scabies, demodectic mange, food allergies, and other skin diseases. The diagnosis can be suspected based on the history, location of skin lesions, and seasonal pattern of occurrence. Skin scrapings, bacterial and fungal cultures, skin biopsy and a trial hypoallergenic test diet should be considered before starting a course of treatment for atopy. It is important to treat and eliminate fleas as flea allergy dermatitis further complicates the condition.
ATOPICA should be given at least 2 hours before or after feeding. Insert the capsule directly into the pet's mouth. If a dose is missed, next dose to be administered (without doubling) as soon as possible, but dose no more than once daily.
ATOPICA will initially be given daily until a satisfactory clinical improvement is seen. This will generally be the case within 4 weeks. If no response is obtained within the first 8 weeks, the treatment should be stopped.
WEIGHT (lbs) / DOSAGE (Btwn 1.5 to 3.0mg/lb. daily)
4 - 6.5lbs: 1 x 10mg
6.6 - 9lbs: 2 x 10mg
9.1- 16lbs: 1 x 25mg
16.1 - 33lbs: 1 x 50mg
33.1 - 64lbs: 1 x 100mg
64.1 -79lbs: 1 x 100mg + 1 x 50mg
79.1 - 121bs: 2 x 100mg
Once the clinical signs of atopic dermatitis are satisfactorily controlled, dose adjustment should only be carried out in consultation with Veterinarian.
ATOPICA contains 10mg, 25mg, 50mg or 100mg Cyclosporine A per capsule.
Do not use ATOPICA in dogs less than six months of age or less than 4.4 lbs (2kg) in weight. ATOPICA is not for use in breeding dogs, pregnant or lactating bitches.
The occurrence of adverse reactions is uncommon. Most common are vomiting and diarrhea. Generally are mild and transient and do not require the cessation of the treatment. Divided dosing or administration with a small amount of food may help to resolve. Other side effects are rare and may include lethargy or hyperactivity, anorexia, skin reactions such as lesions or change of hair coat, red and swollen pinnae, muscle weakness or muscle cramps. These effects generally resolve spontaneously after treatment is stopped.
If any serious effects or other effects not mentioned occur, consult Veterinarian.