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Cardizem SR (Diltiazem SR)

Prescription requiredOnly Available By Prescription
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Top Generic choice

What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Cardizem SR is used to treat angina, high blood pressure, and certain heart rhythm disorders. Diltiazem, the active ingredient, dilates blood vessels, reduces blood pressure, and relieves chest pain. It may also be prescribed for Raynaud's phenomenon, tardive dyskinesia, and as a preventive measure against heart attacks.

Fact Table
Formula C22H26N2O4S
License US DailyMed
Bioavailability 40%
Legal status Rx-Only
Chemical Name Diltiazem SR
Elimination half-life 3–4.5 hours
Dosage (Strength) 60mg, 90mg, 120mg, 120mg (12hrs)
Pregnancy consult a healthcare provider
Brands Cardizem SR
Protein binding Unknown
PubChem CID 39186
MedlinePlus a684027
ChEBI 101278
ATC code C05AE03
DrugBank DB00343
KEGG D07845
Routes of administration By mouth

Buy Cardizem SR (Diltiazem SR) online from online Canadian Pharmacy |


To ensure the safe and effective use of Cardizem SR 120mg, follow as prescribed by your doctor.

Avoid using larger or smaller amounts or taking it for a longer duration than recommended.

Cardizem SR generic is taken orally in the form of capsules. Swallow the whole capsule without crushing, chewing, or breaking it.

If you receive Diltiazem through injection, it will be administered as an infusion into a vein by a healthcare provider.

Do not change your dosage or schedule without consulting your doctor.

Do not abruptly discontinue taking this medication, as sudden cessation may worsen your condition.


Cardizem capsules are available in different strengths of diltiazem hydrochloride in each tablet.


If you are being treated for high blood pressure, continue using Cardizem SR even if you feel well, as high blood pressure often has no noticeable symptoms.

Do not use Cardizem if you have very low blood pressure, "sick sinus syndrome," "AV block" (unless you have a pacemaker), or if you recently had a heart attack with fluid build-up in your lungs.

Inform your doctor if you have kidney disease, liver disease, or congestive heart failure before taking Cardizem.

Be cautious when driving or performing activities that require alertness.

Do not stop taking the medication without consulting your doctor, as suddenly discontinuing it can worsen your condition.


The most common drugs that interact with Cardizem SR are medications used in anesthesia, anti-anxiety medications, beta-blockers, carbamazepine, cimetidine, clonidine, digitalis, quinidine, rifampin, and cholesterol medication called statins. There could be other drugs that interact with Diltiazem SR. Inform your doctor about all the prescription and over-the-counter medications, vitamins, and herbal products you are currently using or plan to start or stop using.

Side Effects

The usage of Cardizem SR may lead to the following side effects. If any of these unfavorable effects occur, it is important to promptly consult a physician:

  • Headache, nausea, hives, fatigue, or flushing
  • Bradycardia or irregular heartbeat
  • Dizziness or feeling lightheaded
  • Chest Pain
  • Shortness of breath

This list does not contain all the possible side effects. Before you buy Cardizem SR, make sure you talk to your doctor about all the other medications you are taking and the potential side effects they could cause.

Frequently asked questions about Cardizem

What is Cardizem?

Cardizem, known in the realm of generics as Diltiazem, is a calcium channel blocker. Its primary function is to impede the influx of calcium ions into cardiac and vascular smooth muscle. By doing so, Cardizem promotes the relaxation of these muscles and expands blood vessels, which helps enhance the flow of blood and oxygen to the heart and lowers the heart's workload.

Does Cardizem lower blood pressure?

Absolutely, Cardizem plays a crucial role in lowering blood pressure. As a calcium channel blocker, it promotes the relaxation and widening of your blood vessels. This allows blood to flow more freely, thereby lowering your blood pressure. It's especially beneficial for individuals dealing with hypertension.

Is Cardizem a beta blocker?

No, Cardizem is not a beta blocker. It belongs to a group of medicines known as calcium channel blockers. While both beta blockers and calcium channel blockers are used to treat similar conditions, like hypertension and certain heart conditions, they do so via different mechanisms. Beta blockers decrease the heart rate and the heart's output of blood, whereas Cardizem primarily works by relaxing and dilating the blood vessels.

Can Cardizem be crushed?

Generally, Cardizem tablets should not be crushed or chewed. The Cardizem SR variant is specially designed to slowly release the medication over time. Crushing or chewing this medication can lead to the release of all the medicine at once, increasing the risk of side effects. For those who have trouble swallowing the tablets, it's best to explore other options. Discuss this with your doctor or pharmacist, or even consider consulting with a trusted online pharmacy like CanPharm for potential alternatives.

Does Cardizem lower heart rate?

Yes, Cardizem does assist in lowering heart rate. By blocking the calcium channels, Cardizem causes the heart muscle to relax, reducing the rate at which the heart beats. This is particularly beneficial for individuals who experience a rapid heart rate due to conditions such as atrial fibrillation.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.