Cyltezo (Adalimumab)

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Fact Table

Fact Table
Formula C6428H9912N1694O1987S46
License US DailyMed
Bioavailability 64% (subcutaneous)
Legal status Prescription drug
Chemical Name Adalimumab
Elimination half-life 10–20 days
Dosage (Strength) 20mg/0.4mL, 40mg/0.8mL
Pregnancy Consult a doctor
Brands Cyltezo
Protein binding Unknown
PubChem CID Not Assigned
MedlinePlus a603010
ChEBI Not Assigned
ATC code L04AB04
DrugBank DB00051
KEGG D02597
Routes of administration Subcutaneous

Cyltezo is a biosimilar to Humira (Adalimumab) and is part of a class of drugs known as biologic disease-modifying antirheumatic drugs (DMARDs). It is an injectable medication designed to treat a variety of autoimmune conditions by inhibiting tumor necrosis factor (TNF), a substance in the body that causes inflammation. Conditions treated by Cyltezo include rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and plaque psoriasis among others. By targeting and blocking the action of TNF, Cyltezo helps to reduce inflammation, pain, and further damage to affected tissues.

Before you buy Cyltezo, it is crucial that you talk to your healthcare provider about potential side effects and Cyltezo cost.

Directions

Cyltezo is administered via subcutaneous injection.

The dosage and frequency depend on the specific condition being treated and the patient's medical profile.

It is crucial to follow your healthcare provider's instructions precisely.

The medication often comes in a prefilled syringe or auto-injector for ease of use. Patients are usually instructed on how to self-administer the injections at home.

Always check the medication for any discoloration or particulate matter before use, and never use it if the product appears compromised.

Ingredients

The active ingredient in Cyltezo is Adalimumab, a monoclonal antibody that specifically targets and neutralizes TNF alpha, thereby reducing inflammatory responses.

Cautions

Before starting Cyltezo, inform your healthcare provider about any medical conditions, especially infections, hepatitis B, nervous system problems, heart failure, or if you have recently received or are scheduled to receive vaccines. Patients should also disclose if they are pregnant, planning to become pregnant, or breastfeeding.

Cyltezo can lower the ability of your immune system to fight infections, leading to an increased risk of serious infections. Patients should be tested for latent tuberculosis before and periodically during treatment with Cyltezo. Monitor for signs of infection, including fever, fatigue, cough, or red, warm, and painful skin areas.

Interactions

Cyltezo autoinjector can interact with other medications, potentially increasing the risk of side effects or affecting how well Cyltezo or the other medications work. It's important to tell your healthcare provider about all the medicines you take, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Caution should be used when combining Cyltezo with other biologic DMARDs, live vaccines, or any medication that affects the immune system.

Side Effects

Common side effects of Cyltezo include injection site reactions (redness, itching, pain), upper respiratory infections, headache, and nausea. Serious side effects can occur and may include severe infections, allergic reactions, heart failure, liver problems, blood disorders, and certain types of cancer. Immediately report any symptoms of these conditions to your healthcare provider.

Frequently Asked Questions about Cyltezo


What is Cyltezo?

Cyltezo is an interchangeable biosimilar to Humira. Both are adalimumab products, and Cyltezo has been tested to ensure it is as effective and safe as Humira.


Is Cyltezo a generic version of Humira?

No, Cyltezo is not a generic version of Humira. It is a biosimilar to Humira and is as effective and safe as Humira.


Are Cyltezo and Adalimumab-adbm the same medicine?

Yes, Cyltezo and Adalimumab-adbm are the same medicine with the same effectiveness and safety.


What should I do if I don’t notice any improvement or experience worsening symptoms after several weeks of using Cyltezo?

If you don’t notice any improvement or experience worsening symptoms after several weeks, consult your doctor to determine if Cyltezo is the appropriate medication.


Can I start taking Cyltezo if I have an infection?

You should not start taking Cyltezo if you have any infection unless your doctor says it is okay. Serious infections have happened in people taking adalimumab products.


What is the function of Cyltezo?

Cyltezo is a TNF-blocker medicine that can lower the ability of your immune system to fight infections.


What support is available for patients starting on Cyltezo?

When starting on Cyltezo, you can find support and resources through the BI Solutions Plus patient support program.