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Esbriet (Pirfenidone)

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Top Generic choice

What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Esbriet (Pirfenidone) is a medication designed to treat adults with mild to moderate idiopathic pulmonary fibrosis (IPF), a chronic and ultimately fatal disease characterized by a progressive decline in lung function. The exact cause of IPF is unknown, and Esbriet works to slow the disease's progression and improve the quality of life for those affected by this condition. This medication has undergone rigorous clinical testing, demonstrating its efficacy and safety in managing the symptoms of IPF.

By targeting the fibrotic process, Esbriet helps to preserve lung function, reduce the severity of symptoms, and enhance the overall well-being of patients. Before you buy Esbriet for the treatment of IPF, you must talk to your healthcare provider about potential side effects and Esbriet cost.

What is IPF?

Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive lung disease characterized by the thickening, scarring (fibrosis), and stiffening of lung tissue, which can lead to severe breathing difficulties over time. The term idiopathic is used because the cause of this condition is unknown.

Fact Table
Formula C12H11NO
License US DailyMed, EU EMA
Bioavailability 46%
Legal status Rx-only
Chemical Name Pirfenidone
Elimination half-life 2.4 hours
Dosage (Strength) 200mg, 267mg, 600mg, 801mg
Pregnancy Consult Doctor
Brands Esbriet
Protein binding 50–58%
PubChem CID 40632
MedlinePlus a615008
ChEBI 32016
ATC code L04AX05
DrugBank Not Available
KEGG D01583
Routes of administration Oral

Buy Esbriet (Pirfenidone) online from online Canadian Pharmacy |


Esbriet is available in both tablet and capsule forms and should be taken with food to minimize the risk of nausea and dizziness. The recommended starting dosage is one 267 mg tablet three times a day, gradually increasing to a maximum of three 801 mg tablets per day over the course of 15 days, depending on your tolerance and response to the medication. It is crucial to follow your healthcare provider's instructions carefully and not to alter the dosage without their guidance.


The active ingredient in Esbriet is Pirfenidone.


Before starting Esbriet or Esbriet generic, it is vital to inform your healthcare provider of your complete medical history, especially if you have liver or kidney issues, are pregnant, planning to become pregnant, or are breastfeeding.

Liver function tests should be conducted before and during treatment with Esbriet, as it can cause elevated liver enzymes, which could indicate liver damage.

Patients should avoid exposure to sunlight and wear sunscreen and protective clothing when outdoors, as Esbriet can increase sensitivity to sunlight and the risk of severe sunburn.


Esbriet can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. It is important to inform your healthcare provider of all prescription and over-the-counter drugs, vitamins, and herbal products you are currently taking.

Specific interactions to be aware of include CYP1A2 inhibitors (such as ciprofloxacin and fluvoxamine) and CYP1A2 inducers (such as omeprazole and rifampicin).

Side Effects

Like all medications, Esbriet can cause side effects, although not everyone will experience them. Common side effects include:

  • Nausea
  • Rash
  • Diarrhea
  • Fatigue
  • Anorexia
  • Dyspepsia (indigestion)
  • Headache
  • Dizziness
  • Vomiting

Frequently Asked Questions about Esbriet (Pirfenidone)

What is Esbriet (Pirfenidone)?

Esbriet (Pirfenidone) is a medication used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). It is designed to slow down the progression of this condition and improve lung function.

How does Esbriet work?

Esbriet works by reducing the production of certain proteins in the body that contribute to the scarring (fibrosis) of lung tissue in IPF. By doing so, it helps to slow down the progression of the disease.

Who can take Esbriet?

Esbriet is typically prescribed for adults who have been diagnosed with idiopathic pulmonary fibrosis (IPF). It is essential to consult a healthcare professional to determine if Esbriet is suitable for your specific medical condition.

What are the common side effects of Esbriet?

Common side effects of Esbriet may include nausea, diarrhea, rash, headache, and fatigue. These side effects are usually mild and can often be managed with adjustments in the dosage or with other medications.

How is Esbriet taken?

Esbriet is usually taken orally, in the form of tablets. The recommended dosage and frequency will be determined by your healthcare provider based on your individual needs.

Can Esbriet cure idiopathic pulmonary fibrosis (IPF)?

Esbriet does not cure IPF, but it can help slow down the progression of the disease and improve lung function. It is important to continue taking Esbriet as prescribed by your healthcare provider, even if you do not experience immediate relief.

Are there any special precautions or interactions with other medications?

Yes, it's essential to inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and supplements. Some medications may interact with Esbriet, so your doctor can adjust your treatment plan accordingly.

Can pregnant or breastfeeding women take Esbriet?

It is not recommended for pregnant or breastfeeding women to take Esbriet unless the potential benefits outweigh the risks. Discuss your situation with your healthcare provider for personalized guidance.

What should I do if I miss a dose of Esbriet?

If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Can I drink alcohol while taking Esbriet?

It is generally recommended to limit or avoid alcohol consumption while taking Esbriet, as alcohol can interact with the medication and may increase the risk of side effects.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.