Euflexxa (Sodium Hyaluronate)
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Description
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Fact Table
| Fact Table | |
|---|---|
| Formula | Not applicable (biologic) |
| License | FDA approved |
| Bioavailability | Not applicable (intra-articular injection) |
| Legal status | Prescription required |
| Chemical Name | Sodium Hyaluronate |
| Elimination half-life | Not applicable (intra-articular injection) |
| Dosage (Strength) | Varies depending on the severity of osteoarthritis |
| Pregnancy | Category C - Risk cannot be ruled out; consult healthcare provider |
| Brands | Euflexxa |
| Protein binding | Not applicable (intra-articular injection) |
| PubChem CID | 24759 (for Sodium Hyaluronate) |
| MedlinePlus | a619014 (for Sodium Hyaluronate) |
| ChEBI | 28246 (for Sodium Hyaluronate) |
| ATC code | M09AX01 |
| DrugBank | DB01279 (Sodium Hyaluronate) |
| KEGG | D00021 (Sodium Hyaluronate) |
| Routes of administration | Intra-articular injection |
Euflexxa (1% sodium hyaluronate) is a non-avian derived hyaluronic acid injectable solution that is specifically designed for the treatment of knee pain in patients suffering from osteoarthritis (OA). Euflexxa is administered directly into the knee joint to help lubricate and cushion the joint, thereby reducing pain and improving joint movement. As a bioengineered product, Euflexxa mimics the natural hyaluronic acid found in the human body, making it a preferred choice for those seeking a treatment option with a reduced risk of allergic reactions.
Before you buy Euflexxa injection, it is crucial that you talk to your healthcare provider about potential side effects and Euflexxa injection cost.
Directions
Euflexxa is administered by a healthcare professional through a series of three injections into the knee joint, with each injection spaced one week apart. It is important to avoid activities such as jogging, heavy lifting, or standing for long periods for 48 hours following each injection. Patients are advised to consult with their healthcare provider to determine the most appropriate treatment schedule based on their individual condition.
Ingredients
The active ingredient in Euflexxa is sodium hyaluronate (1% solution).
Cautions
Before receiving Euflexxa knee injection, patients should inform their healthcare provider about any previous allergies or reactions to hyaluronic acid products. Euflexxa is contraindicated in patients with infections or skin diseases in the area of the injection site or in those with known hypersensitivity to hyaluronic acid preparations.
Interactions
No specific drug interactions with Euflexxa have been identified; however, it is advisable to inform the healthcare provider about all medications, supplements, and herbal products currently being used before starting treatment. Caution should be exercised when combining Euflexxa with other intra-articular injections or therapies to avoid potential complications.
Side Effects
Common side effects of Euflexxa include pain, swelling, or redness at the injection site, headache, and knee swelling or pain.
Frequently Asked Questions about Euflexxa
How does Euflexxa work?
Euflexxa works by supplementing the natural hyaluronic acid in the knee joint, improving the joint's lubricating and shock-absorbing properties, which helps to reduce pain and improve mobility.
How quickly can I expect pain relief after starting Euflexxa?
Some patients may notice improvement after the first injection, but typically, the full benefit of Euflexxa is observed after completing the full course of three injections.
Are there any activities I should avoid after getting Euflexxa injections?
It is recommended to avoid strenuous activities such as high-impact sports and heavy lifting for at least 48 hours following each injection to allow the joint to stabilize.
How long does the treatment effect last?
The effects of Euflexxa can last up to six months, but results may vary depending on the individual's activity level and the severity of their osteoarthritis.
Can Euflexxa cure my osteoarthritis?
Euflexxa is not a cure for osteoarthritis; it is designed to manage the symptoms, particularly pain. It does not reverse joint damage or halt the progression of the disease.
What should I do if I miss a scheduled injection?
If you miss a scheduled injection, contact your healthcare provider as soon as possible to reschedule. It is important to maintain the weekly interval between injections for optimal results.
Can Euflexxa be used with other pain medications?
Yes, Euflexxa can be used in conjunction with other pain medications. Discuss with your healthcare provider the best pain management strategy for your situation.
Is Euflexxa suitable for everyone with knee osteoarthritis?
Euflexxa is suitable for most adults with knee osteoarthritis; however, it is not recommended for those with infections in or around the knee or those with known hypersensitivities to its ingredients.
What are the signs of an allergic reaction to Euflexxa?
Signs of an allergic reaction include difficulty breathing, chest tightness, swelling of the face, lips, tongue, or throat, severe redness or pain at the injection site. If you experience any of these symptoms, seek medical attention immediately.
How is Euflexxa different from other hyaluronic acid-based treatments?
Unlike some other hyaluronic acid treatments that are derived from rooster combs, Euflexxa is bioengineered and does not contain proteins from avian sources, reducing the risk of allergic reactions. This makes it a preferred choice for patients sensitive to avian-derived products.
