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Euflexxa (Sodium Hyaluronate)

Prescription requiredOnly Available By Prescription
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Euflexxa (1% sodium hyaluronate) is a non-avian derived hyaluronic acid injectable solution that is specifically designed for the treatment of knee pain in patients suffering from osteoarthritis (OA). Euflexxa is administered directly into the knee joint to help lubricate and cushion the joint, thereby reducing pain and improving joint movement. As a bioengineered product, Euflexxa mimics the natural hyaluronic acid found in the human body, making it a preferred choice for those seeking a treatment option with a reduced risk of allergic reactions.

Before you buy Euflexxa injection, it is crucial that you talk to your healthcare provider about potential side effects and Euflexxa injection cost.

Fact Table
Formula Not applicable (biologic)
License FDA approved
Bioavailability Not applicable (intra-articular injection)
Legal status Prescription required
Chemical Name Sodium Hyaluronate
Elimination half-life Not applicable (intra-articular injection)
Dosage (Strength) Varies depending on the severity of osteoarthritis
Pregnancy Category C - Risk cannot be ruled out; consult healthcare provider
Brands Euflexxa
Protein binding Not applicable (intra-articular injection)
PubChem CID 24759 (for Sodium Hyaluronate)
MedlinePlus a619014 (for Sodium Hyaluronate)
ChEBI 28246 (for Sodium Hyaluronate)
ATC code M09AX01
DrugBank DB01279 (Sodium Hyaluronate)
KEGG D00021 (Sodium Hyaluronate)
Routes of administration Intra-articular injection

Buy Euflexxa (Sodium Hyaluronate) online from online Canadian Pharmacy |


Euflexxa is administered by a healthcare professional through a series of three injections into the knee joint, with each injection spaced one week apart. It is important to avoid activities such as jogging, heavy lifting, or standing for long periods for 48 hours following each injection. Patients are advised to consult with their healthcare provider to determine the most appropriate treatment schedule based on their individual condition.


The active ingredient in Euflexxa is sodium hyaluronate (1% solution).


Before receiving Euflexxa knee injection, patients should inform their healthcare provider about any previous allergies or reactions to hyaluronic acid products. Euflexxa is contraindicated in patients with infections or skin diseases in the area of the injection site or in those with known hypersensitivity to hyaluronic acid preparations.


No specific drug interactions with Euflexxa have been identified; however, it is advisable to inform the healthcare provider about all medications, supplements, and herbal products currently being used before starting treatment. Caution should be exercised when combining Euflexxa with other intra-articular injections or therapies to avoid potential complications.

Side Effects

Common side effects of Euflexxa include pain, swelling, or redness at the injection site, headache, and knee swelling or pain.

Frequently Asked Questions about Euflexxa

How does Euflexxa work?

Euflexxa works by supplementing the natural hyaluronic acid in the knee joint, improving the joint's lubricating and shock-absorbing properties, which helps to reduce pain and improve mobility.

How quickly can I expect pain relief after starting Euflexxa?

Some patients may notice improvement after the first injection, but typically, the full benefit of Euflexxa is observed after completing the full course of three injections.

Are there any activities I should avoid after getting Euflexxa injections?

It is recommended to avoid strenuous activities such as high-impact sports and heavy lifting for at least 48 hours following each injection to allow the joint to stabilize.

How long does the treatment effect last?

The effects of Euflexxa can last up to six months, but results may vary depending on the individual's activity level and the severity of their osteoarthritis.

Can Euflexxa cure my osteoarthritis?

Euflexxa is not a cure for osteoarthritis; it is designed to manage the symptoms, particularly pain. It does not reverse joint damage or halt the progression of the disease.

What should I do if I miss a scheduled injection?

If you miss a scheduled injection, contact your healthcare provider as soon as possible to reschedule. It is important to maintain the weekly interval between injections for optimal results.

Can Euflexxa be used with other pain medications?

Yes, Euflexxa can be used in conjunction with other pain medications. Discuss with your healthcare provider the best pain management strategy for your situation.

Is Euflexxa suitable for everyone with knee osteoarthritis?

Euflexxa is suitable for most adults with knee osteoarthritis; however, it is not recommended for those with infections in or around the knee or those with known hypersensitivities to its ingredients.

What are the signs of an allergic reaction to Euflexxa?

Signs of an allergic reaction include difficulty breathing, chest tightness, swelling of the face, lips, tongue, or throat, severe redness or pain at the injection site. If you experience any of these symptoms, seek medical attention immediately.

How is Euflexxa different from other hyaluronic acid-based treatments?

Unlike some other hyaluronic acid treatments that are derived from rooster combs, Euflexxa is bioengineered and does not contain proteins from avian sources, reducing the risk of allergic reactions. This makes it a preferred choice for patients sensitive to avian-derived products.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.