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GastroGard Oral Paste (Omeprazole)

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GastroGard Oral Paste is a medication utilized for the treatment and prevention of gastric ulcers in horses and foals that are at least 4 weeks old. It improves and heals gastric ulcers and helps prevent their recurrence. The paste is well-accepted and comes in a flavored formulation that is given daily using an oral syringe.

Typical indications of gastric ulcers comprise reduced appetite, recurring episodes of colic, sporadic instances of loose stools or persistent diarrhea, unhealthy-looking coat, diminished body condition, and decreased performance.

Fact Table
Formula C17H19N3O3S
License US DailyMed
Bioavailability 35–76%
Legal status Rx-Only
Chemical Name Omeprazole
Elimination half-life 1–1.2 hours
Dosage (Strength) 2.28g (1 Syringe)
Pregnancy Consult a healthcare provider
Brands GastroGard Oral Paste
Protein binding 95%
PubChem CID 4594
MedlinePlus a693050
ChEBI 7772
ATC code A02BC01
DrugBank DB00338
KEGG D00455
Routes of administration Oral Paste

Buy GastroGard Oral Paste (Omeprazole) online from online Canadian Pharmacy |


To treat gastric ulcers, GastroGard Paste should be given orally once a day for a duration of 4 weeks. The recommended GastroGard dosage is 1.8 mg of omeprazole per pound of body weight (4 mg/kg).

Before you buy GastroGard for horses make sure you continue the treatment for at least an additional 4 weeks to prevent the recurrence of gastric ulcers.

Administer GastroGard Paste at the recommended daily maintenance dose of 0.9 mg per pound (2 mg/kg).

It is important to note that the recommended dosage is 1.8 mg of omeprazole per pound of body weight (4 mg/kg). By setting the syringe plunger to the appropriate weight marking, you can ensure accurate dosing for the horse's specific weight.

To administer GastroGard Paste for prevention of ulcer recurrence at 0.9 mg per pound (2 mg/kg), set the syringe plunger to the weight marking corresponding to half of the horse's weight in pounds.


  • Before administering the medication, ensure that the horse's mouth is clear of any food or feed.
  • Take off the cover from the tip of the syringe before using it.
  • Insert the syringe into the horse's mouth at the area between the teeth.
  • Press the plunger until it stops at the knurled ring.
  • The dose should be placed on the back of the tongue or deep into the cheek pouch.
  • Ensure that the horse consumes the entire dose.
  • Observe the horse briefly after administration to make sure none of the doses is lost or rejected. If any dose is lost, it's recommended to administer another dose.
  • If there is any remaining content in the syringe after dosing, it can be used on subsequent days until empty.
  • After each use, remember to replace the cap on the GastroGard Oral paste.


Omeprazole is the active ingredient in GastroGard Oral Paste.


Avoid using GastroGard Oral paste in mares that are pregnant or lactating.

It is not recommended to use GastroGard Oral paste in equines weighing less than 70 kg or younger than 4 weeks of age.

When administering the product, it is advised to wear impervious gloves for protection.


There are no known drug-related interactions with GastroGard Paste.

Side Effects

During efficacy trials, no adverse reactions were observed when the drug was administered at a dosage of 1 mg omeprazole per kilogram of body weight for up to 30 days, or at a dosage of 4 mg omeprazole per kilogram of body weight daily for 28 days followed by 2 mg omeprazole per kilogram of body weight daily for an additional 30 days.

Frequently Asked Questions about Gastrogard

How to use Gastrogard for horses?

Once you obtain a prescription from your veterinarian, follow the dosage instructions provided by them. Administer the paste orally using the syringe provided. Give the medication once a day, preferably in the morning before feeding. Make sure to complete the full treatment course as prescribed by your veterinarian.

Does Gastrogard treat hindgut ulcers?

Gastrogard is used to treat gastric ulcers in horses. Consult with a veterinarian for appropriate treatment options if your horse has hindgut ulcers. They may prescribe medications such as sucralfate or misoprostol for the treatment of hindgut ulcers in horses.

How much Gastrogard to give a horse?

It is generally recommended to administer a dosage of 4 mg/kg of omeprazole for horses undergoing treatment. This dosage typically corresponds to one tube of Gastrogard per day for an average-sized horse, and the treatment duration is often 30 days.

What is the difference between Gastrogard and Ulcergard?

Gastrogard and Ulcergard are both medications for gastric ulcers in horses. Gastrogard is used for treatment, while Ulcergard is for prevention. They contain the same active ingredient, omeprazole, but have different packaging and dosing. Gastrogard is given daily for treatment, while Ulcergard is a single dose for prevention.

How long does it take Gastrogard to heal ulcers?

Healing with Gastrogard is often observed within the first two weeks of treatment. By the end of the 30-day treatment period, many ulcers will have healed or shown substantial improvement. It's important to complete the full treatment course as prescribed by your veterinarian, even if the horse's symptoms improve before the treatment is finished.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.