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Fact Table
| Fact Table | |
|---|---|
| Formula | C21H27N5O4S |
| License | US FDA, US DailyMed, EU EMA |
| Bioavailability | 100% |
| Legal status | Prescription drug |
| Chemical Name | Glipizide |
| Elimination half-life | 2 to 5 hours |
| Dosage (Strength) | 5mg, 10mg |
| Pregnancy | Consult a doctor |
| Brands | Glucotrol |
| Protein binding | 98 to 99% |
| PubChem CID | 3478 |
| MedlinePlus | a684060 |
| ChEBI | 5384 |
| ATC code | A10BB07 |
| DrugBank | DB01067 |
| KEGG | D00335 |
| Routes of administration | By Mouth |
Glucotrol (Glipizide) is a medication primarily used to manage type 2 diabetes. It belongs to the class of drugs called sulfonylureas, which work by stimulating the release of insulin from the pancreas and increasing the body's sensitivity to insulin. Glucotrol helps lower blood sugar levels by promoting the utilization of glucose by the body's cells. It is typically prescribed alongside a proper diet and exercise regimen for effective diabetes management.
When planning to buy Glucotrol, it is crucial to consider factors such as effectiveness, potential side effects, and cost.?
What is type 2 diabetes?
Type 2 diabetes is a chronic metabolic disorder characterized by two main factors: insulin resistance and relative insulin deficiency. It is the most common form of diabetes and is influenced by genetic and lifestyle factors. Treatment involves lifestyle modifications, medications, and regular monitoring to manage blood sugar levels and prevent complications.
Directions
The Glucotrol dosage is determined based on your specific medical condition and how you respond to the treatment. Your doctor may advise taking it once daily or twice daily for higher doses.
Take this medication by mouth before breakfast or the first meal, as directed by your doctor.
Start with a low dose and follow your doctor's instructions for dose adjustments.
If you are already taking another diabetes drug, follow your doctor's directions for transitioning to glipizide.
Take the medication regularly at the same time each day to maximize its benefits.
Ingredients
Glipizide is the active ingredient in Glucotrol.
Cautions
Inform your doctor of any allergies you have before taking glipizide.
Discuss your medical history, especially liver disease, kidney disease, thyroid disease, hormonal conditions, and electrolyte imbalance, with your doctor or pharmacist.
Be cautious of potential side effects such as blurred vision, dizziness, or drowsiness due to low or high blood sugar levels.
Limit alcohol intake as it can increase the risk of low blood sugar and potentially interact with glipizide.
Take precautions against sun sensitivity by limiting sun exposure, using sunscreen, and wearing protective clothing.
Discuss the use of glipizide during pregnancy or breastfeeding with your doctor.
Interactions
This medication could have negative drug interactions with aspirin, metformin, sitagliptin, insulin glargine, furosemide, lisinopril, levothyroxine, metoprolol, among others. Before starting your treatment with Glucotrol, it is crucial to inform your doctor about all the medications you are currently taking.
Side Effects
Common Glucotrol side effects may include nausea, vomiting, reduced appetite, diarrhea, constipation, stomach discomfort, headache, and weight gain. If any of these side effects persist or worsen, it is important to inform your doctor promptly.
Frequently Asked Questions about Glucotrol (Glipizide)
Is metformin and Glucotrol the same?
Metformin and Glucotrol (glipizide) are both medications used to manage type 2 diabetes, but they belong to different drug classes and have distinct mechanisms of action. Metformin is a biguanide that reduces glucose production, while Glucotrol is a sulfonylurea that stimulates insulin release. Their usage depends on individual circumstances and should be determined by a healthcare professional.
What is glipizide used for?
Glipizide is a medication primarily used to manage type 2 diabetes. It belongs to a class of drugs called sulfonylureas, which work by stimulating the release of insulin from the pancreas and increasing the body's sensitivity to insulin. Glipizide helps lower blood sugar levels in individuals with type 2 diabetes by assisting the body in utilizing insulin effectively.
How does glipizide work?
Glipizide, as a sulfonylurea medication, works by stimulating the release of insulin from the beta cells in the pancreas. Insulin is a hormone essential for regulating blood sugar levels in the body. When blood sugar levels rise, glipizide helps the beta cells in the pancreas produce and release more insulin into the bloodstream.
Does glipizide lower blood sugar immediately?
Glipizide typically starts working relatively quickly after ingestion, but the onset and duration of its blood sugar-lowering effects can vary. The medication is usually taken orally, and its effects can be observed within 30 minutes to an hour after ingestion. However, it's important to note that glipizide is not meant to provide an immediate or rapid reduction in blood sugar levels like some other medications.
How long does glipizide stay in your system?
The elimination half-life of glipizide, which is the time it takes for half of the medication to be eliminated from the body, is approximately 2 to 4 hours. This means that it takes around 2 to 4 hours for half of the glipizide dose to be metabolized and excreted.
