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Ibrance (Palbociclib)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Ibrance (palbociclib) is a medication designed to combat certain types of breast cancer. Developed by Pfizer, it has been approved by the Food and Drug Administration (FDA) for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer in combination with specific hormonal therapies.

This innovative drug falls under the category of kinase inhibitors, which work by interfering with the processes that cancer cells use to grow and divide. Ibrance targets cyclin-dependent kinases 4 and 6 (CDK 4/6), proteins that are crucial for cancer cell proliferation. By inhibiting these proteins, Ibrance slows down the progression of cancer, offering hope and extended survival for patients battling advanced breast cancer.

Before you buy Ibrance, it is crucial that you talk to your healthcare provider about potential side effects and Ibrance cost.

Fact Table
Formula C24H29N7O2
License FDA approved
Bioavailability 46%
Legal status Prescription drug
Chemical Name Palbociclib
Elimination half-life 29 hours
Dosage (Strength) 75mg, 100mg, 125mg
Pregnancy Consult doctor
Brands Ibrance
Protein binding 85%
PubChem CID 5330286
MedlinePlus a614043
ChEBI 134719
ATC code L01EF01
DrugBank DB09073
KEGG D10468
Routes of administration By mouth

Buy Ibrance (Palbociclib) online from online Canadian Pharmacy |


Ibrance is available in capsule form for oral administration. The dosage and administration schedule should be determined by a qualified healthcare professional based on individual patient factors such as age, weight, overall health, and the specific characteristics of the cancer being treated.

Typically, the recommended dose of Ibrance for most patients is 125 mg taken orally once daily for 21 consecutive days, followed by 7 days off treatment to complete a 28-day cycle. It is important to take Ibrance exactly as prescribed, without altering the dosage or schedule, to ensure optimal treatment outcomes.

Ibrance capsules should be swallowed whole with a glass of water, preferably at the same time each day. They can be taken with or without food, but it is advisable to maintain consistency in the timing of administration to help establish a routine and maximize the drug's effectiveness.


Each capsule of Ibrance contains palbociclib as the active ingredient.


Before starting treatment with Ibrance, it is essential to inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking, including prescription drugs, over-the-counter medicines, herbal supplements, and vitamins.

Women who are pregnant or breastfeeding should not take Ibrance, as it may cause harm to the developing fetus or nursing infant. Effective contraception should be used by both males and females during treatment with Ibrance and for at least three weeks after the last dose.

Patients should be monitored regularly by their healthcare provider while taking Ibrance for any signs of adverse reactions or complications. Dose adjustments or temporary discontinuation of treatment may be necessary based on individual tolerance and response to therapy.


Ibrance may interact with certain medications, potentially affecting their efficacy or increasing the risk of adverse reactions. It is important to inform your healthcare provider about all medications you are currently taking, including prescription drugs, over-the-counter medicines, herbal supplements, and vitamins, to avoid potentially harmful interactions. Some medications that may interact with Ibrance include strong CYP3A inhibitors, such as ketoconazole, itraconazole, clarithromycin, and grapefruit or grapefruit juice; strong CYP3A inducers, such as rifampin, carbamazepine, phenytoin, and St. John's wort; hormonal contraceptives containing estrogen, progestin, or both. This is not an exhaustive list of potential interactions. It is essential to consult with your healthcare provider or pharmacist for personalized recommendations based on your specific medication regimen.

Side Effects

Ibrance medication may cause side effects in some patients. Common side effects of Ibrance include:

  • Fatigue
  • Nausea
  • Diarrhea
  • Loss of appetite
  • Hair thinning or hair loss
  • Infections (such as urinary tract infections or respiratory tract infections)
  • Anemia (low red blood cell count)
  • Neutropenia (low white blood cell count)
  • Thrombocytopenia (low platelet count)
  • Mouth sores

Frequently Asked Questions about Ibrance (palbociclib)

What is Ibrance (palbociclib)?

Ibrance is a prescription medication used to treat certain types of breast cancer in adults.

How does Ibrance work?

Ibrance works by inhibiting proteins called cyclin-dependent kinases (CDKs) 4 and 6, which helps slow the growth of cancer cells.

Who should not take Ibrance?

Women who are pregnant or breastfeeding should not take Ibrance.

What are the common side effects of Ibrance?

Common side effects include low white blood cell count, nausea, fatigue, diarrhea, and hair loss.

How is Ibrance taken?

Ibrance is taken orally, usually once daily for 21 days followed by 7 days off.

Are there any interactions with other medications?

Ibrance may interact with certain medications. It's important to tell your doctor about all other medications you're taking.

What should I do if I miss a dose of Ibrance?

If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule.

How long will I need to take Ibrance?

The length of treatment varies depending on the individual and their response to therapy.

Is Ibrance available as a generic?

As of now, Ibrance is not available as a generic medication.

Where can I find more information about Ibrance?

You can find more information about Ibrance on the manufacturer's website or by talking to your doctor or pharmacist.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.