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Invega Hafyera (Paliperidone Palmitate)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Invega Hayfera is an antipsychotic medication available by prescription and used treat schizophrenia and schizoaffective disorder. This injection is given once every 6 months and may also be prescribed for bipolar disorder and other mental or mood disorders. Paliperodone works to change the effect of chemicals in the brain to limit hallucinations, delusional thoughts, disordered thinking, and other schizophrenia symptoms. Buy Invega Hayfera from Canada and get the lowest Invega Hayfera cost.

What is Schizophrenia?

Schizophrenia is a complex and very serious mental health disorder where the individual is unable to interpret reality normally and has problems with cognition, behaviour, and emotions due to major brain chemistry imbalances. A person with schizophrenia will usually require lifelong treatment and use of antipsychotic medication is typically paired with other mental health treatment approaches.

Fact Table
Formula C39H57FN4O4
License FDA approved
Bioavailability Not applicable (administered intramuscularly)
Legal status Prescription only
Chemical Name Paliperidone Palmitate
Elimination half-life 25-49 days (varies depending on injection site)
Dosage (Strength) 175 mg, 263 mg, 350 mg, 525 mg (paliperidone palmitate per injection)
Pregnancy advice Use only if the potential benefit justifies the potential risk to the fetus
Brands Invega Hafyera
Protein binding 74%
PubChem CID 115237
MedlinePlus Not specifically listed for Invega Hafyera (see Invega Sustenna)
ChEBI Not listed
ATC code N05AX13
DrugBank DB01267
KEGG D05339
Routes of administration Intramuscular only

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Invega Hayfera dosage is to have the injection administered once every 6 months. The injection is administered by a medical professional, and it is injected intramuscularly into the upper arm of buttocks.


The active ingredient in Invega Hayfera is Paliperodone Palmitate.


Let your doctor know any history of liver disease, kidney disease, heart disease, seizures, low white blood cell count, Parkinson's disease, dementia, esophagus or stomach / intestinal blockage disorders, eye problems like cataracts or glaucoma, diabetes, high cholesterol and triglyceride levels, or sleep apnea before Starting on Invega Hayfera.

This medication may promote QT prolongation, a heart rhythm disorder that may case irregular heartbeat or other symptoms that may require medical attention.

Alcohol consumption and all recreational drug use should be avoided while taking Invega Hayfera

Invega Hayfera may make you dizzy or drowsy

This medication may diminish your body's ability to perspire. This can increase the risk of heat stroke for some people depending on their environment.

Women who are pregnant or breast feeding should only use Invega Hayfera if that is approved by a doctor


Negative drug interactions may occur between Invega Hayfera and other Rx medications, including amiodarone, chlorpromazine, moxifloxacin, quinidine, sotalol, procainamide, thioridazine, opioid pain or cough relievers like codeine and hydrocodone, alprazolam, lorazepam, carisoprodol, cyclobenzaprine and antihistamines containing cetirizine or diphenhydramine. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Invega Hayfera online.

Side Effects

Invega Hayfera side effects may occur, and some users may experience drowsiness, dizziness, light headedness, drooling, stomach or abdominal pain, weight gain, or exhaustion. If side effects are experienced, it may be best to stop use and meet with a doctor again to discuss schizoaffective disorder treatment medication alternatives.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088

Frequently Asked Questions about Invega

What is the difference between Invega Sustenna and Invega Hayfera?

While both these medications are Paliperodone injections, the Sustenna is an extended-release version but needs to be injected once monthly. The Invega Hayfera injection is not extended release but users will only need to have 2 injections a year, one every 6 months.

What is the half-life of Invega medication?

The half-life of Invega Hayfera is between 84 to 139 days depending on whether deltoid or gluteal is the administration site.

What type of drug is Invega Hayfera?

Invega Hayfera is in the atypical antipsychotic class of medications.

Is Invega a high-risk medication?

This medication is not dangerous provided the patient has uncompromised renal function and dosage guidelines are adhered to.

What does Invega do to the brain?

Paliperodone is the active medicinal ingredient in Invega Hayfera, and it reorients neurotransmitter chemical messaging in the brain so that the neural miscommunications that cause the delusional thoughts of schizophrenia are weakened or in some cases eliminated entirely.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.