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Ismo (Isosorbide Mononitrate)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Ismo (Isosorbide Mononitrate) belongs to a class of drugs called nitrate vasodilators. Ismo is primarily used to prevent and relieve symptoms of angina pectoris, which is chest pain caused by reduced blood flow to the heart muscles. It works by relaxing and widening the blood vessels, allowing for improved blood flow and reduced strain on the heart.

When planning to buy Ismo as a treatment option for angina pectoris, it is crucial to consider factors such as effectiveness, potential side effects, and price.

Fact Table
Formula C6H9NO6
License FDA-approved
Bioavailability More than 95%
Legal status Prescription drug
Chemical Name Isosorbide mononitrate
Elimination half-life 5 hours
Dosage (Strength) 20mg
Pregnancy Consult healthcare provider
Brands Ismo
Protein binding Less than 5%
PubChem CID 27661
MedlinePlus a682348
ChEBI 6062
ATC code C01DA14
DrugBank DB01020
KEGG D00630
Routes of administration By mouth

Buy Ismo (Isosorbide Mononitrate) online from online Canadian Pharmacy |


To ensure proper usage, take this medication orally as directed by your doctor, typically twice a day. The first dose should be taken when you wake up, followed by the second dose 7 hours later. Stick to the same dosing schedule every day unless your doctor advises otherwise.

To get the most out of Ismo medication, use it at the same times every day.

It is important to consult your doctor before discontinuing the medication. If needed, your doctor may gradually lower your dose.


Ismo uses Isosorbide Mononitrate as the active ingredient.


Before using this medication, share your medical history (especially low blood pressure) and allergies with your doctor.

This medication may cause dizziness. Alcohol or cannabis can intensify dizziness. Avoid driving, operating machinery, or participating in activities that demand alertness until you can do so safely.

During pregnancy, use this medication only when necessary.

Consult your doctor before breastfeeding.


This medication could have negative drug interactions with drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat, vericiguat.

Side Effects

Common side effects of Ismo may include headache, lightheadedness, flushing, low blood pressure, nausea or vomiting, and weakness or fatigue. If any of these side effects persist or become bothersome, it is recommended to inform your doctor.

Frequently Asked Questions about Isosorbide Mononitrate

What is isosorbide mononitrate used for?

Isosorbide mononitrate is a medication used to prevent and relieve chest pain (angina) caused by reduced blood flow to the heart. It works by widening blood vessels, increasing oxygen and blood supply to the heart, and reducing heart workload.

What are the most common side effects of isosorbide mononitrate?

Common side effects of isosorbide mononitrate include headache, dizziness, flushing or warmth of the skin, nausea or vomiting, weakness or fatigue, low blood pressure (hypotension), and occasionally rapid heartbeat.

What should you avoid when taking isosorbide?

When taking isosorbide mononitrate, it is important to avoid alcohol, medications for erectile dysfunction (such as Viagra), and medications for pulmonary hypertension (like Adempas). Grapefruit juice should also be avoided as it can interact with isosorbide mononitrate. It's best to consult with your healthcare provider about any medications or substances to avoid while taking isosorbide mononitrate to ensure your safety and the effectiveness of the treatment.

What is the best time to take isosorbide mononitrate?

It is recommended to take isosorbide mononitrate in the morning. Taking it in the morning helps provide continuous and consistent relief throughout the day, as it maintains a steady level of the medication in your body.

Does isosorbide affect sleep?

Isosorbide mononitrate is unlikely to directly affect sleep. However, it may cause side effects like dizziness that could indirectly impact sleep quality.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.