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Kombiglyze XR (Saxagliptin / Metformin)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Kombiglyze XR is a medication that combines two powerful active ingredients, Saxagliptin and Metformin, to manage and control type 2 diabetes mellitus. This oral prescription medication works synergistically to improve blood sugar levels, ensuring that your body responds better to insulin and reduces the amount of glucose produced by the liver. Kombiglyze XR is meticulously designed to be an extended-release tablet, providing a consistent and prolonged therapeutic effect, ensuring optimal blood sugar management throughout the day.

Before you buy Kombiglyze XR for the management of type 2 diabetes, it is crucial that you talk to your healthcare provider about potential side effects and Kombiglyze cost.

Buy Kombiglyze XR (Saxagliptin / Metformin) online from online Canadian Pharmacy |


Kombiglyze XR should be taken as directed by your healthcare professional, typically once daily with a meal to reduce the risk of an upset stomach. The following dosage and strengths are available:

  • Kombiglyze XR 5mg/500mg
  • Kombiglyze XR 2.5mg/1000mg
  • Kombiglyze XR 5mg/1000mg

Swallow the tablet whole without crushing, chewing, or cutting it. The prescribed dosage of this medication is determined by your health status, how well you respond to the treatment, and any other medications you might be currently taking. Ensure that you follow your doctor's instructions carefully, and do not alter the dosage without your doctor's approval.


Kombiglyze XR is a combination of two active ingredients Saxagliptin and Metformin.


Before taking Kombiglyze XR, inform your doctor if you have any allergies or if you have a history of severe kidney disease, metabolic acidosis, or if you frequently consume alcohol.

Avoid alcohol while taking this medication due to the risk of lactic acidosis.

Elderly patients may be more sensitive to the side effects of this drug, especially the risk of lactic acidosis or low blood sugar.


Some products that may interact with Kombiglyze XR include: dofetilide, cimetidine, and certain drugs that can affect blood sugar levels. Keep a list of all the medication you use and share it with your doctor and pharmacist.

Side Effects

Common side effects of Kombiglyze XR include headache, dizziness, nausea, and stomach upset.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088

Frequently Asked Questions about Kombiglyze

What is the generic for Kombiglyze?

The generic equivalent of Kombiglyze XR is a combination of Saxagliptin and Metformin.

Does Kombiglyze make you lose weight?

Kombiglyze XR is not a weight loss medication. However, Metformin, one of its active ingredients, may cause modest weight loss in some individuals due to an improvement in insulin resistance and a decrease in hunger.

Does Kombiglyze XR cause cancer?

There is no definitive evidence that Kombiglyze XR directly causes cancer. It is essential to discuss any concerns with your healthcare provider to understand the risks and benefits.

How long does it take for Kombiglyze to start working?

Kombiglyze XR starts working shortly after ingestion, but it may take a couple of days to a few weeks to see the full benefits in blood glucose control.

How long does Kombiglyze stay in your system?

The elimination of Kombiglyze XR from your system depends on various factors, including kidney function. On average, it may take about 48 to 72 hours for the medication to be cleared from the body.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.