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Kombiglyze XR (Saxagliptin / Metformin)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Kombiglyze XR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both saxagliptin and metformin is appropriate.

Buy Kombiglyze XR (Saxagliptin / Metformin) online from online Canadian Pharmacy |


Kombiglyze XR should not be used for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

Kombiglyze XR has not been studied in combination with insulin.

Lactic acidosis is a rare, but serious, complication that can occur due to metformin accumulation. The risk increases with conditions such as sepsis, dehydration, excess alcohol intake, hepatic impairment, renal impairment, and acute congestive heart failure.

If acidosis is suspected, Kombiglyze XR should be discontinued and the patient hospitalized immediately.

Side Effects

Patients using Kombiglyze XR mostly complained of having:

  • A headache
  • Flu-like symptoms
  • Soreness in the back of the nose and throat and discomfort when swallowing
  • Difficulty breathing or tightness in the chest
  • Vomiting or diarrhoea
  • Stomach pain or discomfort
  • Swelling of hands, ankles or feet
  • Signs of urinary tract infection
  • Rash
  • Feeling depressed or anxious
  • Signs of anaemia
  • Loss of appetite
  • Loss of taste
  • Increased blood pressure
  • Back pain
  • Joint pain
If you get any of the following symptoms visit your doctor as soon as you can.
  • Signs of hypoglycemia
  • Severe allergic reaction
  • Severe upper stomach pain, with nausea and vomiting
  • Signs and symptoms of heart failure (increased shortness of breath, a rapid increase in weight and swelling of the feet).

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.