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Loestrin (Ethinyl Estradiol / Norethindrone)

Also Known as Minestrin

Prescription requiredOnly Available By Prescription
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What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Loestrin is a contraceptive medication that prevents pregnancy by stopping ovulation and altering the cervical mucus and uterine lining. It is also prescribed for regulating menstrual cycles, reducing cramps, and managing hormone-related conditions like polycystic ovary syndrome (PCOS).

Before you buy Loestrin it is important to consult with a healthcare professional or doctor for proper guidance and usage.

Fact Table
Formula C22H28O3.C18H24O2
License FDA-Approved
Bioavailability 50% - 100%
Legal status Prescription drug
Chemical Name Estradiol/norethisterone acetate
Elimination half-life 12-14 hours
Dosage (Strength) 1.5 / 30mcg, 1.0 / 20mcg, 1.0 / 20mcg
Pregnancy Consult a doctor
Brands Loestrin
Protein binding 37- 61%
PubChem CID Not Assigned specifically for this combination
MedlinePlus a601041
ChEBI Not Assigned specifically for this combination
ATC code G03FA01
DrugBank Not Assigned specifically for this combination
KEGG Not Assigned specifically for this combination
Routes of administration Tablets

Buy Loestrin (Ethinyl Estradiol / Norethindrone) online from online Canadian Pharmacy |


Take this medication once a day by mouth with or without food, at the same time each day.

Follow your doctor's instructions exactly and don't skip any doses. Missing doses or taking the pill at different times can increase the risk of pregnancy.

If you vomit or have diarrhea within a few hours of taking the pill, read the leaflet on what to do if you miss a dose. Vomiting or diarrhea can affect how well the pill works.

Taking the medication after dinner or at bedtime can help if it upsets your stomach. Take it at the same time every day, 24 hours apart.

Your pill pack contains 26 pills with active medication and 2 reminder pills with iron. Take one active pill daily for 26 days, then take one reminder pill with iron daily for 2 days. Start a new pack the day after the last reminder pill, even if you're still having your period or haven't had it. Ask your doctor if you don't get your period.


The active ingredients in Loestrin are Ethinyl Estradiol and Norethindrone.


Inform your doctor if you have any allergies to Ethinyl Estradiol, Norethindrone or any other inactive ingredient.

Disclose your medical history, including any previous or existing conditions such as blood clotting disorders, high blood pressure, abnormal breast exams, cancer, high cholesterol or triglyceride levels, depression, diabetes, gallbladder problems, heart problems, kidney or liver disease, stroke, thyroid problems, unexplained vaginal bleeding, or obesity.

Regularly monitor your blood sugar levels if you have diabetes and report any significant changes or symptoms to your doctor.

Inform your doctor if you have upcoming surgery or if you will be immobile for a prolonged period, as this can increase the risk of blood clots.

Take precautions to protect your skin from excessive sun exposure and use sunscreen or protective clothing to prevent dark spots or skin discoloration.

If you wear contact lenses or have vision problems, consult your eye doctor if you experience any issues while using Loestrin.


Some medications that may interact with birth control Loestrin include anastrozole, exemestane, letrozole, dimercaprol, fezolinetant, ospemifene, tamoxifen, tranexamic acid, ombitasvir, paritaprevir, ritonavir with or without dasabuvir, griseofulvin, modafinil, rifampin, St. John's wort, barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate, nelfinavir, nevirapine, among others.

Side Effects

Loestrin side effects may include nausea, vomiting, headache, spotting between menstrual periods, painful menstruation, weight change, breast tenderness, acne, abdominal pain, anxiety, and depression. Serious side effects, though rare, can include severe headache, chest pain, shortness of breath, and signs of a blood clot. Allergic reactions are rare but possible.

Frequently Asked Questions about Loestrin

Why is Lo Loestrin Fe so expensive?

Lo Loestrin Fe can be expensive for a few reasons. Firstly, it is a brand name medication, which typically carries a higher price tag compared to generic versions. The unique formulation of Lo Loestrin Fe, which includes specific hormones and iron tablets, may contribute to higher manufacturing costs. If you want to buy Loestrin online, you can get the best price on CanPharm.

What kind of birth control is Loestrin?

Loestrin is a type of birth control pill that combines estrogen and progestin hormones. It is taken orally once a day to prevent pregnancy and regulate the menstrual cycle.

Does Loestrin give you periods?

Loestrin is a birth control pill that gives you scheduled withdrawal bleeding, similar to a period, during the week when you don't take active pills. It can also be used to control your menstrual cycle.

Does Loestrin cause weight gain?

Some women may gain weight after starting Lo Loestrin or other combination birth control pills, but there is no clear evidence linking oral contraceptives to weight gain. The weight gain that occurs could be due to factors like fluid retention or lifestyle choices.

Does Loestrin help acne?

Lo Loestrin, a specific combination birth control pill, is known to have acne as a potential side effect. This is attributed to the presence of norethindrone acetate in Lo Loestrin, which may contribute to breakouts.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.