Matulane (Procarbazine)

Prescription Required
Generic
Dose Size & Price Qty
50mg
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Fact Table

Fact Table
Formula C12H19N3O
License FDA-approved
Bioavailability Well absorbed from the gastrointestinal tract
Legal status Prescription only (Rx)
Chemical Name Procarbazine
Elimination half-life Approximately 10 minutes (parent compound), metabolites vary
Dosage (Strength) Capsules: 50 mg
Pregnancy advice Contraindicated; Category D by FDA
Brands Matulane
Protein binding Low (<10%)
PubChem CID 4915
MedlinePlus a682094
ChEBI 8064
ATC code L01XX04
DrugBank DB01168
KEGG D08421
Routes of administration Oral

Matulane is a Hodgkins lymphoma treatment medication available by prescription and it is often prescribed along with other medications as part of an advanced-stage cancer treatment regimen. Procarbazine is an alkylating drug, and it works by making cancer cells unable to make the proteins and genetic material needed for the cells to grow and survive. Matulane is usually prescribed for patients with Stage 3 or Stage 4 Hodgkin's lymphoma. Buy Matulane from Canada and Canpharm and get the lowest Matulane cost on it.

What is Hodgkin's Lymphoma?

Hodgkin's lymphoma is a type of blood cancer that affects the lymphatic system. Lymphocytes (white blood cells) increase in numbers exponentially and mutate into abnormal and cancerous Reed-Sternberg cells causing swollen lymph nodes. There are four Hodgkin's lymphoma subtypes, with nodular sclerosing Hodgkin lymphoma, mixed cellularity Hodgkin lymphoma, lymphocyte-rich Hodgkin lymphoma, and lymphocyte depleted Hodgkin lymphoma. This cancer tends to occur most frequently in people between the ages of 20 to 40 or then after 65.

Directions

The standard dosage is to take Matulane 50mg 1 or 2x daily for an initial 2-week treatment period. Use will then be stopped for a time and repeated. This will be explained in detail in your prescription, and you should always take your medication exactly as indicated in it.

Do not chew or crush tablets. Always take whole with water.

Ingredients

The active ingredient in Matulane is Procarbazine.

Cautions

Let your doctor know of any history of kidney or liver disease, bleeding problems, recurrent infections, high blood pressure, or are undergoing radiation treatment before starting on Matulane

High blood pressure risk may require following a very specific diet while using Matulane, and you should avoid food and beverages that are high in tyramine

Use of this medication may make you drowsy or dizzy

Limit alcohol consumption while using Matulane

Smoking cigarettes or other tobacco products may increase your risk of lung cancer while using Matulane

Interactions

Negative drug interactions may occur between Matulane and other Rx medications, including diethylpropion, atomoxetine, methylphenidate, apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, dextromethorphan, methyldopa, metoclopramide, tetrabenazine, valbenazine, meperidine, methadone, tapentadol, rizatriptan, sumatriptan, entacapone, levodopa, tolcapone, maprotiline, mirtazapine, fluoxetine, paroxetine, duloxetine, venlafaxine, amitriptyline, and doxepin.

Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Matulane online.

Side Effects

Matulane side effects may occur, and some users may experience nausea, vomiting, appetite loss, constipation, sleeping difficulties, muscle or joint pain, or darkening of the skin. If side effects are experienced, you may want to stop use and meet with a doctor again to discuss Hodgkin lymphoma treatment medication alternatives.


Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088


Frequently Asked Questions about Matulane (Procarbazine)


What is the brand name for Matulane?

The brand name for this medication is Procarbazine.


Who is the manufacturer of Matulane?

The manufacturer of this medication is Leadiant Biosciences, Inc.


What foods to avoid when taking Procarbazine?

You should avoid eating foods that are high in Tyramine while you are using Matulane. These include avocados, bananas, figs, papaya, raisins, sauerkraut, aged or fermented meats, wine and tap beer, aged cheeses, soy sauce, miso soup, fava beans, bean curd, yogurts, and any foods containing yeast extracts.


What type of medicine is Procarbazine?

Procarbazine is an alkylating medication used to slow and disable cancerous cell growth.


What is the mechanism of Procarbazine?

Procarbazine promotes the breakdown of DNA in cells so that they cannot grow or duplicate to expand and grow the cancer.


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