Mirena

Prescription Required
Brand
Dose Size & Price Qty
52mg
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Fact Table

Fact Table
Formula C21H28O2
License US DailyMed
Bioavailability 85–100%
Legal status Rx-only
Chemical Name Levonorgestrel
Elimination half-life 24–32 hours
Dosage (Strength) 52mg
Pregnancy Consult Doctor
Brands Mirena
Protein binding 98%
PubChem CID 13109
MedlinePlus a610021
ChEBI 6443
ATC code G03AC03
DrugBank DB00367
KEGG D00950
Routes of administration Device

Mirena is a hormonal intrauterine device (IUD) that provides long-term birth control. It's a T-shaped plastic frame inserted into the uterus, where it releases levonorgestrel, a type of hormone progestin. This hormone thickens cervical mucus to prevent sperm from reaching or fertilizing an egg, thins the uterine lining, and partially suppresses ovulation. Mirena is effective for up to seven years and is FDA-approved.

Mirena is used for contraception for up to 8 years and can be used by women whether or not they have had children. Additionally, it is used for up to 5 years to treat heavy menstrual bleeding in women who opt for intrauterine birth control.

Before you Buy Mirena IUD it is important that you talk to your healthcare provider about its effectiveness and potential side effects.

Directions

Mirena is inserted through the vagina into the uterus by a doctor. Some pain, dizziness, and minor vaginal bleeding may occur during insertion, and these symptoms should be reported if they persist for more than 30 minutes. After insertion, the IUD should not interfere with sexual intercourse, tampon or menstrual cup use, or other vaginal medications. Regular check-ups, including annual pelvic exams and Pap smears, are recommended. Periods may become irregular for the first 3 to 6 months, and users should notify their doctor if a period is missed for 6 weeks or if pregnancy is suspected. The IUD can come out by itself, so users should check for the removal strings after each menstrual period.

Ingredients

Mirena contains levonorgestrel, a female hormone that can cause changes in the cervix and uterus. It does not contain estrogen. The device consists of a T-shaped polyethylene frame with a steroid reservoir containing 52 mg of levonorgestrel. After insertion, it releases approximately 21 mcg/day of levonorgestrel, which decreases to about 11 mcg/day after five years and 7 mcg/day after eight years.

Cautions

Mirena should not be used during pregnancy, in cases of abnormal vaginal bleeding, pelvic infection, certain uterine or cervical problems, breast or uterine cancer, liver disease or liver tumor, or if one has a weak immune system. It should not be used as emergency birth control. If left in place during pregnancy, it could cause severe infection, miscarriage, premature birth, or death of the mother. The hormone in Mirena may also cause unwanted effects in a female newborn. Users should not use Mirena if they are allergic to levonorgestrel, silicone, silica, silver, barium, iron oxide, or polyethylene.

Interactions

Some drugs can affect blood levels of levonorgestrel, making Mirena less effective. Users should inform their doctor about all their current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.

Side Effects

Common side effects include pelvic pain, irregular menstrual periods, changes in bleeding patterns or flow, vaginal swelling or infection, pain or bleeding during IUD insertion, ovarian cysts, stomach pain, nausea, vomiting, bloating, headache, migraine, depression, mood changes, back pain, breast tenderness, weight gain, acne, oily skin, changes in hair growth, loss of interest in sex, and puffiness in the face, hands, ankles, or feet.

Serious side effects requiring immediate medical attention include allergic reactions, severe lower stomach pain, severe cramps or pelvic pain, extreme dizziness, heavy or ongoing vaginal bleeding, pale skin, weakness, easy bruising or bleeding, fever, chills, jaundice, and sudden numbness or weakness.


Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088


Frequently Asked Questions about Mirena (Intrauterine Device)


What is Mirena IUD?

Mirena is an intrauterine device (IUD), a small, T-shaped device placed in the uterus to prevent pregnancy.


Does Mirena placement hurt?

Placement may cause pain, bleeding, or dizziness. If symptoms persist beyond 30 minutes, Mirena may require repositioning or removal.


Can I use Mirena for less than 8 years?

Yes, Mirena can be removed anytime, but another birth control method should be used if pregnancy is undesired.


Who should not use Mirena?

Mirena is not suitable for those with certain health conditions like untreated pelvic infections, certain cancers, liver disease, or a history of pelvic inflammatory disease.


What are serious side effects of Mirena?

Serious side effects include ectopic pregnancy, life-threatening infection, pelvic inflammatory disease, uterine perforation, and expulsion.


What are common side effects of Mirena?

Common side effects include changes in menstrual bleeding, missed periods, ovarian cysts, abdominal pain, headache, and vaginal discharge.


How does Mirena affect menstrual periods?

Initially, periods may become irregular with potential spotting or light bleeding. Over time, bleeding generally lessens and periods may stop entirely.


Does Mirena protect against HIV or STIs?

No, Mirena does not offer protection against HIV or other sexually transmitted infections.


Can tampons or menstrual cups be used with Mirena?

Yes, but care should be taken not to displace Mirena's threads during change.


Is it safe to breastfeed while using Mirena?

Breastfeeding is generally safe with Mirena, though a slight risk of decreased milk production and increased risk of uterine perforation during breastfeeding exists.


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