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Mycobutin (Rifabutin)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Mycobutin (rifabutin) is an antibiotic medication primarily used in the treatment of certain bacterial infections. It belongs to a class of drugs known as rifamycins and works by inhibiting the growth of bacteria. Mycobutin is highly effective against Mycobacterium avium complex (MAC) infections, which can occur in individuals with weakened immune systems, such as those with HIV/AIDS.

Before you buy Mycobutin, it is crucial that you talk to your healthcare provider about potential side effects and Mycobutin cost.

Fact Table
Formula C46H62N4O11
License US FDA (and others)
Bioavailability 12-20%
Legal status Prescription (Rx)
Chemical Name Rifabutin
Elimination half-life 45 hours (approx.)
Dosage (Strength) 150mg
Pregnancy Category B (consult a doctor)
Brands Mycobutin
Protein binding ~85%
PubChem CID 441342
MedlinePlus a693009
ATC code J04AB04
DrugBank DB00479
KEGG D00482
Routes of administration Oral

Buy Mycobutin (Rifabutin) online from online Canadian Pharmacy |


It is crucial to follow your healthcare provider's instructions precisely when taking Mycobutin. The dosage and duration of treatment may vary depending on the severity of the infection and other medical factors.

Typically, Mycobutin is taken once or twice daily with food to enhance absorption and minimize potential stomach upset. It is essential to swallow and not crush or chew the capsules whole with a full glass of water.

Even if you start feeling better before completing the prescribed course of Mycobutin, continue taking it as directed by your healthcare provider. Stopping the medication prematurely could lead to the reoccurrence of the infection or the development of antibiotic resistance.


The active ingredient in Mycobutin 150 mg capsules is rifabutin.


Some precautions to consider when using Mycobutin include:

Mycobutin may cause liver toxicity in some individuals, particularly those with pre-existing liver conditions. Your healthcare provider may perform regular liver function tests while you are taking Mycobutin to monitor for any signs of liver damage.

Some individuals may experience allergic reactions to Mycobutin, resulting in symptoms such as rash, itching, swelling, or difficulty breathing.

It is essential to discuss the risks and benefits of using Mycobutin during pregnancy or while breastfeeding with your healthcare provider. Mycobutin may pass into breast milk and could potentially harm a nursing infant.


Mycobutin can interact with a variety of medications, supplements, and substances. Ley your healthcare provider know about all medications you are currently taking to avoid potential interactions. Some common interactions include Antiretroviral Drugs (such as ritonavir and efavirenz), Antifungal Medications (such as ketoconazole and itraconazole), Blood Thinners. These are just a few examples of potential interactions with Mycobutin. Always consult your healthcare provider or pharmacist for personalized advice regarding drug interactions.

Side Effects

Common side effects of Mycobutin may include:

  • Nausea and Vomiting
  • Diarrhea
  • Headache
  • Changes in Urine Color
  • Rash

Frequently Asked Questions about Mycobutin (Rifabutin)

What is Mycobutin (Rifabutin)?

Mycobutin (Rifabutin) is a medication used for the prevention and treatment of certain types of bacterial infections.

How does Mycobutin work?

Mycobutin works by stopping the growth of bacteria. It is an antibiotic that belongs to a class of drugs known as rifamycins.

What is Mycobutin used for?

Mycobutin is primarily used for the prevention of disseminated Mycobacterium avium complex (MAC) disease in patients with advanced HIV infection.

How should I take Mycobutin?

Mycobutin is usually taken orally once a day. The dosage may vary based on your medical condition and response to treatment.

What are the possible side effects of Mycobutin?

Some common side effects include nausea, vomiting, or gastrointestinal upset. If these persist or worsen, you should contact your doctor.

Who should not take Mycobutin?

Individuals with certain medical conditions or allergies may be advised not to take Mycobutin. Always consult your healthcare provider before starting any new medication.

Are there any interactions with other drugs?

Yes, Mycobutin can interact with other drugs, affecting their levels or effects. Always inform your healthcare provider about all the medications you are currently taking.

Can Mycobutin be used for active Tuberculosis?

While not its primary indication, Mycobutin can be used off-label for the treatment of active Tuberculosis in combination with other antitubercular agents.

What forms does Mycobutin come in?

Mycobutin is available in capsule form and as an oral solution.

How should I store Mycobutin?

Mycobutin should be stored as per the instructions on the packaging or as advised by your healthcare provider.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.