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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ocrevus (ocrelizumab) is a prescription medication designed specifically for the treatment of multiple sclerosis (MS). Approved by the FDA, Ocrevus targets the CD20-positive B cells, a type of immune cell that plays a key role in the pathological processes of MS. This medication is recommended for all relapsing types of MS, such as clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, as well as for primary progressive MS.
Before you buy Ocrevus infusion, it is crucial that you talk to your healthcare provider about potential side effects and Ocrevus infusion cost.
| Fact Table | |
|---|---|
| Formula | C6516H10042N1732O2025S42 |
| License | FDA approved |
| Bioavailability | 100% (intravenous) |
| Legal status | Prescription only |
| Chemical Name | Ocrelizumab |
| Elimination half-life | Approximately 26 days |
| Dosage (Strength) | 300 mg and 600 mg intravenous infusion |
| Pregnancy | Should not be used during pregnancy |
| Brands | Ocrevus |
| Protein binding | Not determined |
| PubChem CID | Not available |
| MedlinePlus | ocrelizumab |
| ChEBI | Not available |
| ATC code | L04AA36 |
| DrugBank | DB11988 |
| KEGG | D10406 |
| Routes of administration | Intravenous |
Ocrevus is administered as an intravenous (IV) infusion by a healthcare professional experienced in the treatment of neurological disorders. The initial Ocrevus dosage is split into two separate infusions, given two weeks apart. Each infusion lasts for several hours. After the initial dose, subsequent doses are typically administered once every six months.
Prior to each infusion, patients may be given pre-medication to minimize the risk of infusion-related reactions. These may include a steroid, an antihistamine, and possibly an antipyretic.
It is essential to follow your healthcare provider's instructions regarding preparation for and timing of these infusions. Monitoring for reactions during and after the infusion is crucial.
The active ingredient in Ocrevus is ocrelizumab.
Before starting treatment with Ocrevus, discuss your medical history with your healthcare provider, particularly if you have:
Patients should be screened for hepatitis B virus infection prior to initiating treatment with Ocrevus. Ocrevus can increase the risk of infections, including potentially serious infections, so monitoring for symptoms of infection is important.
Ocrevus can interact with other medications, vaccines, and certain medical treatments, potentially altering their effects. It is important to inform all healthcare providers of your use of Ocrevus. Notable interactions include live or live-attenuated vaccines and other immunosuppressive or immunomodulating therapies.
While Ocrevus has been a beneficial medication for many, it can cause side effects. Common side effects include:
What is Ocrevus?
Ocrevus (ocrelizumab) is a monoclonal antibody used for the treatment of multiple sclerosis (MS), a central nervous system (CNS) disorder.
How does Ocrevus work?
Ocrevus works by targeting a specific protein, called CD20, that exists on the surface of immature and mature B-lymphocytes.
Is Ocrevus chemotherapy?
No, Ocrevus is not chemotherapy. It’s a targeted treatment that works by binding to a protein called CD20 on the surface of B-lymphocytes.
What is Ocrevus used for?
Ocrevus is used to treat multiple sclerosis (MS) in adults, including relapsing forms of MS, clinically isolated syndrome, relapsing-remitting disease, active secondary progressive disease, and primary progressive MS.
How long can you stay on Ocrevus?
The duration of Ocrevus treatment is decided between you and your doctor. It has shown a favorable and manageable safety profile over a 7-year follow-up in real-world data.
Can you take Ocrevus if you are JCV positive?
Yes, you can still take Ocrevus if you are JCV positive, but you should discuss the risks and benefits with your doctor.
How long does Ocrevus suppress the immune system?
Ocrevus suppresses the immune system for a few months after stopping treatment.
How will I feel after an Ocrevus infusion?
After an Ocrevus infusion, you may experience side effects like fatigue and headache. You will be monitored for at least 1 hour after your infusion for any side effects or infusion reactions.
Why is Ocrevus so expensive?
The high cost of Ocrevus is due to various factors including the cost of research and development, manufacturing, and the fact that it treats a rare disease.
How is Ocrevus administered?
Ocrevus is administered by intravenous infusion by a healthcare professional.
Does Ocrevus cause hair loss?
Hair loss is not commonly reported as a side effect of Ocrevus.
