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Pomalyst (Pomalidomide)

Prescription requiredOnly Available By Prescription
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Pomalyst, also known by its generic name pomalidomide, is an immunomodulatory drug mainly prescribed for treating multiple myeloma in patients who have undergone at least two previous therapies. These therapies include lenalidomide and a proteasome inhibitor, and the patients must have shown disease progression either on or within 60 days after the last treatment. Pomalyst works by promoting immune responses that help to slow or stop the growth of cancer cells. It also blocks the blood supply to the cancer cells, which helps in reducing their growth.

Before you buy Pomalyst, it is crucial that you talk to your healthcare provider about potential side effects and Pomalyst cost.

Fact Table
Formula C13H11N3O4
License FDA approved
Bioavailability High (73%)
Legal status Prescription Drugs (Rx-only)
Chemical Name 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Elimination half-life 9.5 hours
Dosage (Strength) 1 mg, 2 mg, 3 mg, or 4 mg capsules
Pregnancy Contraindicated (severe risk of birth defects)
Brands Pomalyst
Protein binding 12-44%
PubChem CID 16041339
MedlinePlus a613038
ChEBI 67352
ATC code L04AX06
DrugBank DB08910
KEGG D09965
Routes of administration Oral

Buy Pomalyst (Pomalidomide) online from online Canadian Pharmacy |


Pomalyst is taken orally, usually in capsule form. The standard dosing regimen involves taking Pomalyst on specific days of a 28-day cycle, but this can vary based on the specific needs and conditions of the patient. The medication is often taken once daily, with or without food, typically at bedtime to reduce the risk of side effects such as dizziness or drowsiness.

Follow your healthcare provider's instructions precisely. Commonly, the medication is taken daily for 21 days followed by a 7-day rest period. This cycle is repeated as directed by your doctor. Swallow the capsules whole with water.


Pomalyst uses pomalidomide as its active ingredient.


Pomalyst can cause fetal harm and is contraindicated in pregnant women. It is a part of the Pomalyst REMS program, requiring women of reproductive potential to use specific forms of contraception and undergo regular pregnancy tests before, during, and after treatment.

Increased risk of venous thromboembolism (VTE) including deep vein thrombosis and pulmonary embolism. Antithrombotic prophylactic treatment should be considered.

Continuous monitoring of blood cell counts through regular blood tests is necessary.

It is important to closely observe patients for any indications of infection and provide immediate treatment.


Pomalyst has the potential to interact with other medications, which can alter how your medications work or increase your risk for serious side effects. It is essential to discuss all medications, supplements, and vitamins you are taking with your healthcare provider. Notable interactions include CYP1A2 Inhibitors (e.g., fluvoxamine) and CYP1A2 Inducers (e.g., smoking tobacco).

Side Effects

Common side effects include:

  • Fatigue and Weakness
  • Constipation or Diarrhea
  • Nausea and Vomiting
  • Respiratory Infections
  • Dizziness and Confusion

Frequently Asked Questions about Pomalyst (Pomalidomide)

What is Pomalyst?

Pomalyst, also known as pomalidomide, is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma.

What is Pomalyst used for?

Pomalyst is used to treat multiple myeloma and AIDS-related Kaposi sarcoma, especially when other medications have not been successful.

Is Pomalyst chemo?

Yes, Pomalyst is considered a chemotherapy drug.

How long does Pomalyst stay in your system?

Pomalyst can stay in your system for approximately 1 to 2 days.

Does Pomalyst cause hair loss?

Hair loss is not a common side effect of Pomalyst.

Does Pomalyst cause weight gain?

Weight gain is possible when taking Pomalyst, especially when it is taken with the drug dexamethasone.

How does Pomalyst work?

Pomalyst works by improving your immune system’s ability to fight the growth of cancer. It also targets and kills the cancer cells and cuts off their blood supply.

How long can you take Pomalyst?

The duration of Pomalyst treatment can vary based on the individual’s response and tolerance to the medication. It’s typically taken as a long-term treatment.

How long does it take Pomalyst to work?

Pomalyst begins working after the first dose.

What are the side effects of Pomalyst?

Common side effects of Pomalyst include fatigue, weakness, low blood cell counts, constipation, nausea, and shortness of breath. Serious side effects can include blood clots, liver problems, lung problems, and nerve numbness or weakness.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.