Rectiv Ointment (Glyceryl Trinitrate)
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Description
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Fact Table
| Fact Table | |
|---|---|
| Formula | C3H5N3O9 |
| License | FDA approved |
| Bioavailability | Less than 1% |
| Legal status | Prescription Drugs |
| Chemical Name | Glyceryl Trinitrate |
| Elimination half-life | 3 minutes |
| Dosage (Strength) | 0.4% Ointment |
| Pregnancy | Use only if clearly needed and potential benefits outweigh the risks |
| Brands | Rectiv Ointment |
| Protein binding | Minimal |
| PubChem CID | 4510 |
| MedlinePlus | a601086 |
| ChEBI | 28787 |
| ATC code | C01DA02 |
| DrugBank | DB00727 |
| KEGG | D00515 |
| Routes of administration | Topical |
Rectiv Ointment is a prescription medication specifically formulated for the treatment of moderate to severe pain associated with chronic anal fissures. An anal fissure is a small tear in the skin lining the opening of the anus which can cause severe pain and bleeding during bowel movements. Rectiv, with its active ingredient nitroglycerin, helps by relaxing the smooth muscles around the blood vessels to promote blood flow to the area, aiding the healing process and alleviating pain.
Before you buy Rectiv ointment, it is crucial that you talk to your healthcare provider about potential side effects and Rectiv ointment price.
Directions
Before beginning treatment with Rectiv Ointment, consult with your healthcare provider to ensure it is appropriate for your condition.
Apply approximately 1 inch (375 mg of ointment) inside the anal canal every 12 hours, or as directed by your healthcare provider.
Treatment duration typically spans up to 3 weeks, depending on the response and advisement of your healthcare provider.
Wash hands thoroughly before and after applying the ointment. Use a finger cot or disposable surgical glove to apply the ointment.
Ingredients
Active Ingredient: Nitroglycerin (0.4%)
Cautions
Do not use if you have a known allergy to nitroglycerin or any components of the ointment.
Caution is advised in patients with low blood pressure, as nitroglycerin can cause further reductions in blood pressure.
Nitroglycerin commonly causes headaches, which can be severe. Your doctor may recommend adjusting your dosage or providing medication to counteract this side effect.
If you are pregnant or breastfeeding, it is important to speak with your healthcare provider before using this medication.
Interactions
Phosphodiesterase Type 5 Inhibitors (e.g., Viagra, Cialis): Concurrent use can cause severe drops in blood pressure. Avoid using these medications within 24 hours of applying Rectiv Ointment.
Antihypertensives: Enhanced effects of blood pressure lowering drugs might occur, requiring dose adjustments.
Alcohol: Avoid alcohol as it can exacerbate the blood pressure-lowering effects of nitroglycerin.
Side Effects
Common side effects include:
- Headache
- Dizziness
- Weakness
- Nausea
- Anal irritation
Frequently Asked Questions about Rectiv Ointment
What is Rectiv Ointment used for?
Rectiv Ointment is used to treat pain associated with chronic anal fissures.
How quickly does Rectiv Ointment work?
Some patients may notice improvement in symptoms within a few days of consistent use, although the full effect might take up to several weeks.
Can Rectiv Ointment be used during pregnancy?
The safety of Rectiv Ointment during pregnancy has not been fully established. Pregnant women should consult their healthcare provider before use.
Can Rectiv Ointment cure anal fissures permanently?
Rectiv Ointment is intended to relieve pain and facilitate healing but may not cure anal fissures permanently. Lifestyle changes and other treatments may be necessary for complete resolution.
Does Rectiv Ointment have any contraindications?
Yes, Rectiv is contraindicated in patients with severe anemia, increased intracranial pressure, or hypersensitivity to nitroglycerin.
Can children use Rectiv Ointment?
The safety and efficacy of Rectiv Ointment in pediatric patients have not been established. Consult a pediatrician before use.
What should I do if I miss a dose?
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
Are there any specific storage conditions for Rectiv Ointment?
Store Rectiv Ointment at room temperature, away from direct sunlight and moisture. Keep the tube tightly closed when not in use.
Can I use other anal medications along with Rectiv Ointment?
Consult your healthcare provider before combining Rectiv with other anal medications to avoid interactions and increased side effects.
What should I avoid while using Rectiv Ointment?
Avoid consuming alcohol, as it can increase the likelihood of low blood pressure and other side effects. Also, avoid using erectile dysfunction medications like Viagra within 24 hours of using Rectiv.
