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Rectiv Ointment (Glyceryl Trinitrate)

Prescription requiredOnly Available By Prescription
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Rectiv Ointment is a prescription medication specifically formulated for the treatment of moderate to severe pain associated with chronic anal fissures. An anal fissure is a small tear in the skin lining the opening of the anus which can cause severe pain and bleeding during bowel movements. Rectiv, with its active ingredient nitroglycerin, helps by relaxing the smooth muscles around the blood vessels to promote blood flow to the area, aiding the healing process and alleviating pain.

Before you buy Rectiv ointment, it is crucial that you talk to your healthcare provider about potential side effects and Rectiv ointment price.

Fact Table
Formula C3H5N3O9
License FDA approved
Bioavailability Less than 1%
Legal status Prescription Drugs
Chemical Name Glyceryl Trinitrate
Elimination half-life 3 minutes
Dosage (Strength) 0.4% Ointment
Pregnancy Use only if clearly needed and potential benefits outweigh the risks
Brands Rectiv Ointment
Protein binding Minimal
PubChem CID 4510
MedlinePlus a601086
ChEBI 28787
ATC code C01DA02
DrugBank DB00727
KEGG D00515
Routes of administration Topical

Buy Rectiv Ointment (Glyceryl Trinitrate) online from online Canadian Pharmacy |


Before beginning treatment with Rectiv Ointment, consult with your healthcare provider to ensure it is appropriate for your condition.

Apply approximately 1 inch (375 mg of ointment) inside the anal canal every 12 hours, or as directed by your healthcare provider.

Treatment duration typically spans up to 3 weeks, depending on the response and advisement of your healthcare provider.

Wash hands thoroughly before and after applying the ointment. Use a finger cot or disposable surgical glove to apply the ointment.


Active Ingredient: Nitroglycerin (0.4%)


Do not use if you have a known allergy to nitroglycerin or any components of the ointment.

Caution is advised in patients with low blood pressure, as nitroglycerin can cause further reductions in blood pressure.

Nitroglycerin commonly causes headaches, which can be severe. Your doctor may recommend adjusting your dosage or providing medication to counteract this side effect.

If you are pregnant or breastfeeding, it is important to speak with your healthcare provider before using this medication.


Phosphodiesterase Type 5 Inhibitors (e.g., Viagra, Cialis): Concurrent use can cause severe drops in blood pressure. Avoid using these medications within 24 hours of applying Rectiv Ointment.

Antihypertensives: Enhanced effects of blood pressure lowering drugs might occur, requiring dose adjustments.

Alcohol: Avoid alcohol as it can exacerbate the blood pressure-lowering effects of nitroglycerin.

Side Effects

Common side effects include:

  • Headache
  • Dizziness
  • Weakness
  • Nausea
  • Anal irritation

Frequently Asked Questions about Rectiv Ointment

What is Rectiv Ointment used for?

Rectiv Ointment is used to treat pain associated with chronic anal fissures.

How quickly does Rectiv Ointment work?

Some patients may notice improvement in symptoms within a few days of consistent use, although the full effect might take up to several weeks.

Can Rectiv Ointment be used during pregnancy?

The safety of Rectiv Ointment during pregnancy has not been fully established. Pregnant women should consult their healthcare provider before use.

Can Rectiv Ointment cure anal fissures permanently?

Rectiv Ointment is intended to relieve pain and facilitate healing but may not cure anal fissures permanently. Lifestyle changes and other treatments may be necessary for complete resolution.

Does Rectiv Ointment have any contraindications?

Yes, Rectiv is contraindicated in patients with severe anemia, increased intracranial pressure, or hypersensitivity to nitroglycerin.

Can children use Rectiv Ointment?

The safety and efficacy of Rectiv Ointment in pediatric patients have not been established. Consult a pediatrician before use.

What should I do if I miss a dose?

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.

Are there any specific storage conditions for Rectiv Ointment?

Store Rectiv Ointment at room temperature, away from direct sunlight and moisture. Keep the tube tightly closed when not in use.

Can I use other anal medications along with Rectiv Ointment?

Consult your healthcare provider before combining Rectiv with other anal medications to avoid interactions and increased side effects.

What should I avoid while using Rectiv Ointment?

Avoid consuming alcohol, as it can increase the likelihood of low blood pressure and other side effects. Also, avoid using erectile dysfunction medications like Viagra within 24 hours of using Rectiv.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.