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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Rocaltrol (Calcitriol) is a form of vitamin D that is used to regulate calcium and phosphate levels in the body. It is primarily prescribed for the treatment of various conditions related to calcium and bone metabolism.
Rocaltrol is often prescribed to individuals with chronic kidney disease who have low levels of calcitriol. It helps the body absorb calcium from the diet and promotes the proper functioning of the parathyroid glands, which are responsible for regulating calcium levels. By maintaining adequate calcium levels, Rocaltrol helps prevent conditions such as osteoporosis, osteomalacia (softening of the bones), and renal osteodystrophy (a bone disease associated with kidney dysfunction).
When planning to buy Rocaltrol, it is crucial to consider factors such as effectiveness, potential side effects, and the Rocaltrol cost.
| Fact Table | |
|---|---|
| Formula | C27H44O3 |
| License | US FDA, US DailyMed, EU EMA |
| Bioavailability | 70.6±5.8% |
| Legal status | Prescription drug |
| Chemical Name | Calcitriol |
| Elimination half-life | 5–8 hours |
| Dosage (Strength) | 0.25mcg, 0.5mcg |
| Pregnancy | Consult a doctor |
| Brands | Rocaltrol |
| Protein binding | 99.9% |
| PubChem CID | 5280453 |
| MedlinePlus | a682335 |
| ChEBI | 17823 |
| ATC code | A11CC04 |
| DrugBank | DB00136 |
| KEGG | D00129 |
| Routes of administration | By Mouth |
Take this medication as instructed by your doctor, either with or without food.
It is typically taken once a day. Use this medication regularly at the same time each day.
If you are using the liquid form of the medication, make sure to measure your dose using a special measuring spoon or device.
Rocaltrol uses Calcitriol as its active ingredient.
Before using Rocaltrol, it is important to disclose the following information to your doctor:
Your medical history, particularly if you have high calcium levels, heart disease, or kidney disease.
Any allergies you may have, including allergies to Calcitriol or other vitamin D products.
Unless your doctor advises otherwise, it is important to ensure you drink adequate amounts of fluid.
During pregnancy, use this medication only if necessary, and discuss the potential risks and benefits with your doctor.
This medication could have negative drug interactions with burosumab, digoxin, digitalis, magnesium-containing medications such as antacids and milk of magnesia, phosphate binders, vitamins, and nutritional supplements (especially calcium and vitamin D), ketoconazole, phenobarbital, phenytoin.
Rocaltrol can potentially cause side effects, although not everyone experiences them. Common side effects of Rocaltrol may include nausea or vomiting, loss of appetite, stomach pain or discomfort, constipation, dry mouth, increased thirst, headache, weakness, metallic taste in the mouth, and increased urination.
What is Rocaltrol prescribed for?
Rocaltrol is primarily prescribed for conditions related to calcium and vitamin D metabolism. It is commonly used to treat hypocalcemia (low levels of calcium in the blood) and secondary hyperparathyroidism (overactive parathyroid gland) in patients with chronic kidney disease or undergoing dialysis.
What is calcitriol?
Calcitriol is the active form of vitamin D that helps regulate calcium and phosphorus levels in the body. It is prescribed to treat conditions like low calcium levels and certain kidney diseases.
Can you take calcitriol and calcium together?
Yes, it is possible to take calcitriol and calcium together. When prescribed together, calcitriol helps increase calcium absorption from the diet, while calcium supplements provide an additional source of calcium to support adequate levels in the body. However, it is important to follow the recommendations of your healthcare provider regarding the appropriate amounts of calcitriol and calcium based on your specific needs and medical condition.
Can you take calcitriol and vitamin D together?
Calcitriol is the active form of vitamin D, so taking calcitriol and additional vitamin D supplements together may not be recommended in most cases. Combining high doses of both can potentially lead to excessive levels of vitamin D in the body, which can be harmful.
How does calcitriol affect blood phosphate levels?
Calcitriol, the active form of vitamin D, plays a crucial role in maintaining appropriate levels of phosphate in the blood. It accomplishes this by influencing the absorption of phosphate from the intestines and the reabsorption of phosphate in the kidneys.
