Spiriva (Tiotropium)

Chemical Name: Tiotropium ( ty-OH-tro-pee-um)

SPIRIVA is indicated for long term, once a day maintenance treatment for bronchospasm (wheezing or difficulty in breathing) that is associated with Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis and emphysema. SPIRIVA works by relaxing the muscles in your airways and enlarging the airways. This way more air can move in/out of your lungs, in turn helping you breathe better. This medication comes with a handheld inhalation device because the capsule contains dry powder that is inhaled through the mouth. SPIRIVA is only used to prevent bronchospasm attacks. Do not use it during an attack because it will not work quickly enough -- use a fast-acting inhaler instead.

Available with prescription only.

Directions

SPIRIVA is generally used once a day, every day, to help maintain any breathing problems relating to COPD and to reduce the possibility of COPD flare-ups. SPIRIVA is a dry powder that comes in a capsule form. Patients must insert the capsule in the HandiHaler and inhale the powder through your mouth. Avoid getting this medication in your eyes. If this does happen, immediately rinse with water. Do not swallow the capsule. Carefully read the Instructions for use.

Cautions

It is important to consult with your general practitioner (GP) before taking SPIRIVA HandiHaler, as it may not be the right treatment method for you. Share your medical history and conditions, including:

• allergies to any medications
• kidney problems
• have glaucoma
• an enlarged prostate
• problems passing urine
• pregnancy or plan to become pregnant
• breast-feeding or plan to breast-feed
• severe allergy to milk proteins
• any medications you may be taking including prescription, non-prescription, eye drops, vitamins, and herbal supplements

Side Effects

SPIRIVA can cause serious side effects, including allergic reaction. Symptoms may include raised red patches on your skin (hives), itching, rash, and swelling of the lips, tongue, or throat that may cause difficulty in breathing or swallowing. If you have these symptoms of an allergic reaction, stop taking SPIRIVA and call your doctor immediately or visit a hospital emergency room.

Additional side effects of SPIRIVA include:

• upper respiratory tract infection
• dry mouth
• sinus infection
• sore throat
• non-specific chest pain
• urinary tract infection (UTI)
• indigestion
• runny nose
• constipation
• increased heart rate
• blurred vision

This is not a complete list of all the possible side effects with SPIRIVA. Tell your general practitioner if you experience any side effect that bothers you or that are persistent.