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Stendra (Avanafil)

Also Known as Spedra

Prescription requiredOnly Available By Prescription
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What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Stendra is a medication for erectile dysfunction (ED), available by prescription. It helps men achieve an erection and enjoy intimacy with their partner. ED occurs due to insufficient blood flow to the penis, even with sexual stimulation. Avanafil, a PDE-5 inhibitor drug, dilates the blood vessels in the penis, promoting increased blood flow to the corpus cavernosum. Buy Stendra from Canada through Canpharm for the lowest cost.

What is Erectile Dysfunction?

Erectile dysfunction is a condition in which a man cannot develop an erection, even in an intimate environment with a partner. While it can be a natural part of aging, factors like poor vascular health or being overweight can exacerbate it. Erectile dysfunction results from reduced blood flow to the penis, preventing it from becoming rigid and elongated—a problem absent in men without this sexual health issue.

Fact Table
Formula C23H26ClN7O3
License FDA-approved (2012)
Bioavailability Approximately 4% (oral route)
Legal status Rx-Only
Chemical Name Avanafil
Elimination half-life Approximately 5 hours
Dosage (Strength) 50 mg, 100 mg, 200 mg
Pregnancy Not applicable (intended for use in adult men)
Brands Stendra
Protein binding 99%
PubChem CID 9869929
MedlinePlus a614015
ChEBI Not available
ATC code G04BE10
DrugBank DB06237
KEGG D03217
Routes of administration Oral

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The standard dosage of Stendra is one tablet taken 30 to 45 minutes before anticipated sexual activity.


The active ingredient in Stendra is Avanafil.


Inform your doctor of any history of angina, chest pain, heart failure, stroke, kidney or liver disease, high or low blood pressure, chronic dehydration, penile conditions such as Peyronie's disease, prolonged erection (priapism), eye problems like NAION or retinitis pigmentosa, bleeding disorders, or stomach ulcers before starting Stendra.

This medication may cause dizziness.

It is advisable to limit alcohol consumption while using this medication.

Be aware of the medication's expiry date.


Negative drug interactions may occur between Stendra and other prescription medications, including alprazolam, amlodipine, atorvastatin, azelastine, bupropion, nebivolol, tadalafil, ciprofloxacin, doxycycline, fluticasone, lisinopril, losartan, meclizine, metformin, methocarbamol, metoprolol, omeprazole, prednisone, simvastatin, tamsulosin, sildenafil, and cetirizine. Inform your doctor of all medications you are currently taking before obtaining a prescription and purchasing Stendra online.

Side Effects

Possible side effects of Stendra include headaches, flushing, and dizziness. If you experience side effects, consider stopping use and consulting your doctor to discuss alternative treatments for erectile dysfunction.

Frequently Asked Questions about Stendra

What is Stendra used for?

Stendra is used to treat erectile dysfunction (ED). It helps improve blood flow to the penis to help achieve and maintain an erection.

How does Stendra work?

Stendra works by inhibiting the enzyme PDE5, which allows blood vessels to relax and increase blood flow to the penis during sexual stimulation. This helps produce and maintain an erection.

How long does Stendra last?

The effects of Stendra typically last for up to 6 hours. This allows for a broader window to engage in sexual activity.

What are the side effects of Stendra?

Common side effects of Stendra include headaches, flushing, runny nose, and back pain. More serious side effects are rare but can include hearing loss and vision issues.

Can Stendra be taken with food?

Yes, Stendra can be taken with or without food. Taking it with a high-fat meal may increase absorption.

How long before sex should I take Stendra?

Stendra is fast-acting, so it can be taken 30 minutes before sexual activity. Taking it too far in advance increases the risk of side effects.

Can I drink alcohol while taking Stendra?

It is recommended to avoid heavy drinking while taking Stendra, but light drinking should not cause issues. Heavy drinking increases the risk of side effects.

Is Stendra safe to take with other medications?

Stendra has minimal interactions with other drugs, but should not be taken with nitrates commonly used for heart conditions or alpha-blockers for blood pressure.

Is a prescription required for Stendra?

Yes, Stendra is only available by prescription in the U.S. Speak to your doctor to see if a prescription is appropriate.

What strengths does Stendra come in?

Stendra comes in 50 mg, 100 mg, and 200 mg tablets to provide options in dosing for different Patient needs.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.