Taltz (Ixekizumab)
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Description
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Fact Table
| Fact Table | |
|---|---|
| Chemical Name | Ixekizumab |
| License | FDA Approved |
| Bioavailability | 60-80% (subcutaneous administration) |
| Legal Status | Prescription Drugs |
| Elimination Half-Life | 13 days |
| Dosage (Strength) | 80 mg/mL in a prefilled autoinjector or syringe |
| Pregnancy | Should be used only if the benefits outweigh potential risks |
| Brands | Taltz |
| Protein Binding | Not applicable (monoclonal antibody) |
| PubChem CID | 119796298 |
| DrugBank | DB11640 |
| KEGG | D10576 |
| Routes of Administration | Subcutaneous |
Taltz is a prescribed drug designed to manage various inflammatory disorders, such as moderate to severe plaque psoriasis in adults eligible for systemic therapy or phototherapy, active psoriatic arthritis, and active ankylosing spondylitis. Taltz belongs to a class of drugs known as interleukin inhibitors and specifically targets interleukin-17A (IL-17A), a protein that plays a key role in inflammation.
Taltz is designed to provide relief from the symptoms of these conditions, such as skin plaques, joint pain, and stiffness, by reducing the inflammatory responses in the body. This medication is available in the form of an injection and is intended for subcutaneous administration. Before you buy Taltz injection, it is crucial that you talk to your healthcare provider about potential side effects and Taltz price.
Directions
Taltz is administered by subcutaneous injection. The usual dose for adults with plaque psoriasis or psoriatic arthritis is 160 mg (two 80 mg injections) as an initial dose, followed by 80 mg every two weeks for 12 weeks, and then 80 mg every four weeks. For ankylosing spondylitis, the dosing schedule is the same as for psoriatic arthritis. Always use Taltz exactly as your doctor has prescribed.
Ingredients
Active Ingredient: Ixekizumab
Cautions
Taltz should not be used by individuals with a known hypersensitivity to ixekizumab or any of the other ingredients in the formulation. It is also not recommended for patients with active tuberculosis or other severe infections such as sepsis, and active inflammatory bowel disease. Prior to starting treatment, patients should be evaluated for tuberculosis risk.
Monitor for signs and symptoms of infection during and after treatment with Taltz. If a serious infection develops, consider stopping Taltz until the infection resolves.
Live vaccines should not be given concurrently with Taltz. Discuss vaccination with your healthcare provider before starting treatment.
Interactions
Taltz may interact with live vaccines and certain other drugs. It is important to tell your doctor about all medications, supplements, and herbs you are taking before starting Taltz. Avoid receiving live vaccines during treatment with Taltz as it may increase the risk of developing an infection.
Side Effects
Common side effects of Taltz medication includes:
- Injection site reactions (redness, itching)
- Upper respiratory tract infections
- Nausea
- Fungal infections
Frequently Asked Questions about Taltz (Ixekizumab)
What is Taltz?
Taltz, also known as ixekizumab, is a medication used to treat certain autoimmune disorders such as plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis.
Is Taltz a biologic?
Yes, Taltz is a biologic medication. It is made from parts of living organisms.
Is Taltz an immunosuppressant?
Yes, Taltz is an immunosuppressant. It works by reducing inflammation and affecting the immune system.
How to inject Taltz?
Taltz is given as a subcutaneous injection, usually in the thighs or stomach area. It can be self-administered or given by a caregiver.
Why is Taltz so expensive?
The cost of Taltz can vary based on several factors such as your treatment plan, insurance coverage, the specialty pharmacy you use, and whether Taltz has a savings program.
How does Taltz work?
Taltz works by binding to interleukin 17A (IL-17A), a protein involved in inflammation. This helps reduce inflammation and improve symptoms of the conditions it treats.
Does Taltz cause hair loss?
Hair loss is not commonly reported as a side effect of Taltz. However, psoriasis, a condition that Taltz treats, can lead to temporary hair loss.
How long can Taltz be unrefrigerated?
Taltz can be kept at room temperature not exceeding 86°F (30°C) for up to 5 days.
How long does it take for Taltz to work?
Taltz starts to improve symptoms within about 1-2 weeks, with significant improvements usually seen after 12 weeks of treatment.
How long does Taltz stay in your system?
The exact duration Taltz stays in the system is not specified, but similar biologic medications can stay in the system for up to several months.
