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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tukysa inhibits HER2, a gene that can play a role in the development of breast cancer. Tukysa is used together with other medicines (trastuzumab and capecitabine) to treat HER2-positive breast cancer. This combination chemotherapy is used when the cancer has spread to other parts of the body or cannot be removed with surgery. Tukysa is usually given after other treatments have failed.
Take Tukysa exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. You may take Tukysa with or without food. Swallow the tablet whole and do not crush, chew, or break it. Do not use a cracked or broken tablet. Take the medicine at the same time each day, about every 12 hours. If you vomit shortly after taking Tukysa, do not take another dose. Wait until your next scheduled dose time to take the medicine again. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. You will need frequent blood tests to check your liver function. Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative. Throw away any unused Tukysa tablets 3 months after you first opened the bottle.
The active ingredient in Tukysa is tucatinib.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tukysa may affect the way your other medicines work, and other medicines may affect the way Tukysa works. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions and allergies.
Get emergency medical help if you have signs of an allergic reaction to Tukysa: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: • severe or ongoing diarrhea; • pain, blisters, bleeding, or severe rash in the palms of your hands or the soles of your feet; • blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; • a seizure; • liver problems - loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or • low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Your cancer treatments may be delayed or permanently discontinued if you have certain side effects. Common Tukysa side effects may include: • diarrhea; • nausea, vomiting, stomach pain, loss of appetite; • anemia; • mouth sores; • rash; • headache, tiredness; or • abnormal liver function tests. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.