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Verzenio (Abemaciclib)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Description

Verzenio is a breast cancer treatment medication available by prescription and is used to treat metastatic breast cancer. The medication's active ingredient is Abemaciclib, and it is a CDK4 / CDK6 inhibitor drug that slows the growth and progression of cancer cells. Verzenio may be taken in combination with an aromatase inhibitor medication depending on whether or not the woman is also going through hormone therapy to limit the amount of estrogen hormone that is available to fuel the growth of cancerous cells in the body. Buy Verzenio from Canpharm and get the lowest Verzenio cost on it.

Fact Table
Formula C27H32F2N8
License US FDA
Bioavailability 45%
Legal status Rx-Only
Chemical Name Abemaciclib
Elimination half-life 18.3 hrs
Dosage (Strength) 50mg, 100mg, 150mg, 200mg
Pregnancy Consult your healthcare provider
Brands Verzenio
Protein binding 96.3%
PubChem CID 46220502
MedlinePlus a617049
ChEBI Not Assigned
ATC code L01EF03
DrugBank DB12001
KEGG D10688
Routes of administration By mouth

Buy Verzenio (Abemaciclib) online from online Canadian Pharmacy | CanPharm.com

Directions

The standard dosage for Verzenio medication is to take 1 tablet 2x daily, and with or without food. Always take your medication at the dosage and frequency indicated in your prescription.

Ingredients

The active ingredient in Verzenio is Abemaciclib.

Cautions

Let your doctor know if you have any history of liver disease, bleeding or blood clotting problems, recurrent infections, or if you have recently had an immunization before starting on Verzenio.

Avoid people who have contagious infections like chickenpox, measles, and flu while taking Verzenio.

Medication may make you drowsy or dizzy.

Avoid eating grapefruit or drinking grapefruit juice while using this medication.

Temporary hair loss may occur while using Verzenio, but it is rare.

Pregnant or breastfeeding women or women who plan to become pregnant should only use Verzenio if their doctor approves it.

Interactions

Negative drug interactions may occur between Verzenio and other Rx medications, including amlodipine, anastrozole, Ativan (lorazepam), atorvastatin, hushart, Cymbalta (duloxetine), dexamethasone, doxycycline, exemestane, famotidine, Faslodex (fulvestrant), gabapentin, Imodium (loperamide), letrozole, levothyroxine, losartan, melatonin, metformin, omeprazole, ondansetron, pantoprazole, Xgeva (denosumab), Zofran (ondansetron), Zometa (zoledronic acid).

Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Verzenio online.

Side Effects

Side effects from using Verzenio may occur, and some users may experience nausea, vomiting, weight loss, constipation, appetite loss, headache, or changes in taste. If side effects are experienced, you may want to stop use and meet with a doctor again to discuss metastatic breast cancer treatment medication options.


Frequently asked questions about Verzenio


What is Verzenio used for?

Verzenio is a medication primarily used in the treatment of a specific type of breast cancer known as HR-positive, HER2-negative breast cancer. It's typically prescribed when the cancer has spread to other parts of the body (metastasized) or when it has progressed following hormonal therapy. If you're considering to buy Verzenio, it's important to understand its purpose and potential benefits.


Is Verzenio chemotherapy?

No, Verzenio is not a traditional chemotherapy drug. It's classified as a targeted therapy, specifically a CDK4/6 inhibitor. Unlike chemotherapy, which broadly targets all rapidly dividing cells, Verzenio specifically blocks certain proteins (CDK4 and CDK6) that promote cancer cell growth. This targeted approach often results in fewer side effects compared to traditional chemotherapy.


Does Verzenio cause weight gain?

Weight changes, including weight gain, can occur with Verzenio treatment. However, everyone's reaction to medication is unique, and not all individuals will experience this side effect. It's crucial to maintain a balanced diet and regular exercise while on Verzenio medication, and report any significant weight changes to your healthcare provider.


Does Verzenio kill cancer cells?

Verzenio works by inhibiting the function of proteins called CDK4 and CDK6. These proteins are vital for cell division. By blocking these proteins, Verzenio can halt the division and growth of cancer cells. While it may not directly kill cancer cells, it can significantly slow their growth and proliferation.


How does Verzenio work?

Verzenio operates by blocking the activity of enzymes known as cyclin-dependent kinases 4 and 6 (CDK4/6). These enzymes are crucial in regulating cell division. By inhibiting CDK4/6, Verzenio disrupts the cell cycle, preventing cancer cells from dividing and growing. This mechanism makes Verzenio a valuable tool in managing certain types of breast cancer. Remember, the Verzenio cost should be considered in the context of its potential benefits and your overall treatment plan.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.