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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Voxzogo, scientifically known as Vosoritide, marks a groundbreaking advancement in treating Achondroplasia, the most common form of dwarfism. As a synthetic analog of C-type Natriuretic Peptide (CNP), Voxzogo stimulates bone growth in children and adolescents who are still growing. This innovative medication offers hope to those affected by Achondroplasia, aiming to improve their quality of life by addressing the genetic condition at its root.
Before you buy Voxzogo, you must talk to your healthcare provider about potential side effects and Voxzogo price.
| Fact Table | |
|---|---|
| Formula | C176H290N56O51S3 |
| License | US DailyMed |
| Bioavailability | Unknown |
| Legal status | Prescription drug |
| Chemical Name | Vosoritide |
| Elimination half-life | 21.0 to 27.9 minutes |
| Dosage (Strength) | 0.4 mg; 0.56 mg; 1.2 mg |
| Pregnancy | Consult a doctor |
| Brands | Voxzogo |
| Protein binding | Unknown |
| PubChem CID | Not available because this is not a discrete structure |
| MedlinePlus | a622012 |
| ChEBI | Not Assigned |
| ATC code | M05BX07 |
| DrugBank | DB11928 |
| KEGG | D11190 |
| Routes of administration | Subcutaneous injection |
Before administering Voxzogo, ensure that the patient is well-hydrated and has adequate food intake.
The recommended Voxzogo dosing is based on the patient's actual body weight.
Voxzogo is administered subcutaneously once daily.
Reconstitute the lyophilized powder in a single-dose vial according to the instructions provided. The injection volume depends on the patient's weight and the concentration of reconstituted Voxzogo.
Monitor growth closely and adjust the dosage based on the patient's actual body weight. Discontinue treatment upon closure of epiphyses.
Voxzogo contains vosoritide as its active ingredient.
Before starting Voxzogo, patients should undergo a thorough medical evaluation.
Caution is advised for individuals with underlying heart conditions, as Voxzogo can influence blood pressure and heart rate.
It is also important to monitor for signs of allergic reactions to Vosoritide or any of the medication's components.
Pregnant or breastfeeding women should discuss potential risks and benefits with their healthcare provider.
Regular follow-ups and monitoring of growth rates are recommended throughout the treatment period.
No specific drug interactions have been reported with Voxzogo. You must inform your healthcare provider about all medications, supplements, or herbal products you are taking.
The most common adverse reactions associated with Voxzogo include:
What is Voxzogo (Vosoritide)?
Voxzogo (Vosoritide) is a C-type natriuretic peptide (CNP) analog that increases linear growth in pediatric patients with achondroplasia with open epiphyses.
How does Voxzogo work?
Voxzogo works alongside the body’s natural CNP to stimulate the CNP signaling pathway to promote bone growth.
Who can use Voxzogo?
Voxzogo is intended for children aged five years and older whose growth plates are still open.
How is Voxzogo administered?
Voxzogo is taken daily as an injection under the skin, administered by a caregiver after a healthcare provider determines the caregiver can assist Voxzogo.
What are the common side effects of Voxzogo?
The most common side effects include injection site reactions, high levels of blood alkaline phosphatase shown in blood tests, vomiting, joint pain, decreased blood pressure, and stomach ache.
Are there any contraindications for Voxzogo?
There are no known contraindications for Voxzogo.
What precautions should be taken before administering Voxzogo?
To reduce the risk of decreased blood pressure and associated symptoms, patients should eat a meal and drink 8 to 10 ounces of fluid within 1 hour before receiving Voxzogo.
What is the dosage form and strength of Voxzogo?
Voxzogo is available for injection in strengths of 0.4 mg, 0.56 mg, or 1.2 mg of vosoritide as a lyophilized powder in a single-dose vial for reconstitution.
