Vyepti (Eptinezumab)

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Fact Table

Fact Table
Formula C6352H9838N1694O1992S46
License US DailyMed
Bioavailability 100%
Legal status Prescription drug
Chemical Name Eptinezumab
Elimination half-life 27 days
Dosage (Strength) 100mg/mL
Pregnancy Consult a doctor
Brands Vyepti
Protein binding Unknown
PubChem CID Not Assigned
MedlinePlus Not Assigned
ChEBI Not Assigned
ATC code N02CD05
DrugBank DB14040
KEGG D11303
Routes of administration Intravenous

Vyepti (Eptinezumab) is a prescription medication designed for the preventive treatment of migraine in adults. It belongs to a class of drugs known as monoclonal antibodies, specifically targeting the calcitonin gene-related peptide (CGRP) pathway, a key player in the onset of migraine headaches. Administered via intravenous infusion, Vyepti works by blocking the action of CGRP, thus reducing the frequency, severity, and duration of migraine episodes.

Before you buy Vyepti, it is crucial that you talk to your healthcare provider about potential side effects and Vyepti cost.

Directions

Vyepti dosage is administered as a 100 mg/100 mL or 300 mg/100 mL intravenous infusion over approximately 30 minutes, once every three months. This treatment should only be administered by a healthcare professional in a medical setting equipped to manage potential reactions to the infusion.

Ingredients

Active Ingredient: Eptinezumab.

Cautions

Vyepti is contraindicated in patients with a history of hypersensitivity to eptinezumab or any of its components. Prior to receiving Vyepti, inform your healthcare provider if you:

Have any allergies to medications.

Are pregnant, planning to become pregnant, or are breastfeeding.

Have any other medical conditions, especially infections or immune system disorders.

Interactions

Inform your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Vyepti may interact with other medications, potentially altering the way your medications work or increasing your risk for serious side effects. Currently, there are no well-documented interactions with Vyepti. However, ongoing research may update this information.

Side Effects

Common side effects of Vyepti include:

  • Nasopharyngitis (common cold)
  • Allergic reactions
  • Nausea

In rare cases, more serious side effects may occur, such as:

  • Hypersensitivity reactions, including rash, itching, or swelling (especially of the face, tongue, or throat)
  • Severe dizziness
  • Trouble breathing

Frequently Asked Questions about Vyepti


How effective is Vyepti in preventing migraines?

Clinical trials have shown Vyepti to be effective in reducing the frequency of migraine days in adults when administered every three months.


Can I take Vyepti while pregnant or breastfeeding?

The effects of Vyepti during pregnancy and breastfeeding are not fully known. Consult your healthcare provider for a risk assessment.


How quickly does Vyepti work?

Some patients may experience a reduction in migraine frequency in as little as one week after the infusion, with maximum benefits observed over time.


Is there any downtime after receiving a Vyepti infusion?

Most individuals can resume normal activities immediately after the infusion. However, it is recommended to monitor any reactions for a short period post-infusion.


Can Vyepti cure migraines?

Vyepti is not a cure for migraines but is used to reduce the frequency and severity of migraine episodes.


What should I do if I experience a severe side effect?

If you experience severe or life-threatening side effects, seek immediate medical attention.


Is it safe to drive after receiving Vyepti?

Vyepti does not typically affect your ability to drive or operate machinery, but individual reactions to the medication can vary.


How long do I need to continue Vyepti treatment?

The duration of Vyepti treatment depends on your response to the medication and should be discussed with your healthcare provider.


Can children receive Vyepti?

Vyepti is approved for use in adults over 18. Its safety and efficacy in children have not been established.


What happens if I miss a dose?

If a dose is missed, schedule an appointment with your healthcare provider to receive it as soon as possible. Do not double doses.