Zepzelca (Lurbinectedin)

Zepzelca (Lurbinectedin) is a breakthrough therapy for patients with metastatic Small Cell Lung Cancer (SCLC) that has progressed after platinum-based chemotherapy. This innovative oncology medication works by inhibiting the transcription process in cancer cells, which disrupts their ability to proliferate. Zepzelca offers hope to those facing limited treatment options, providing a targeted approach to manage aggressive cancer effectively. Each pack contains a sterile solution for infusion, meticulously prepared to ensure safety and efficacy in cancer care.

Before you buy Zepzelca, it is crucial that you talk to your healthcare provider about potential side effects and Zepzelca Cost.

Directions

Zepzelca is administered intravenously by a healthcare professional experienced in cancer treatments. The recommended dose is based on body surface area, typically given once every three weeks. Before infusion, Zepzelca must be diluted in a specific volume of 0.9% sodium chloride solution. It is essential to follow the healthcare provider's instructions regarding preparation and administration precisely to ensure optimal outcomes.

Preparation:

• Calculate the Zepzelca dosing based on body surface area.
• Use aseptic technique to prepare the diluted solution.
• Inspect the solution for particulate matter and discoloration before administration.

Administration:

• Administer as an intravenous infusion over 60 minutes.
• Avoid extravasation.
• Follow with post-infusion monitoring for adverse reactions.

Ingredients

Each vial of Zepzelca contains 4 mg of lurbinectedin as a lyophilized powder.

Cautions

Zepzelca should be used with caution in patients with pre-existing liver or kidney impairment, as it may require dose adjustments.

It is not recommended for pregnant or breastfeeding women due to potential harm to the fetus or infant.

Patients should be monitored for hematologic toxicity; dose modifications may be necessary in cases of neutropenia or thrombocytopenia.

Avoid use in combination with live vaccines.

Interactions

Zepzelca can interact with other medications, potentially affecting its efficacy or increasing the risk of adverse effects. It is crucial to inform your healthcare provider about all medications, supplements, and herbal products you are taking. Specifically, avoid the use of strong CYP3A4 inhibitors or inducers, as they can alter Lurbinectedin's plasma concentration.

Side Effects

Like all medications, Zepzelca can cause side effects, although not everyone experiences them. Common side effects include:

• Fatigue
• Nausea
• Decreased appetite
• Diarrhea
• Neutropenia (low levels of white blood cells)
• Anemia (low red blood cell counts)
• Thrombocytopenia (low platelet counts)

Severe side effects may include liver toxicity and pneumonitis. Report any unusual symptoms or side effects to your healthcare provider immediately.