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What is Adalimumab – How Does Adalimumab Work?

what is adalimumab

Most occupations it is acceptable if you get it wrong sometimes. Any more frequently and you may be getting into dismissal territory though. But then there are jobs where you simply can’t be getting it wrong ever. Think air traffic controller for example. Your immune system isn’t salaried, and you certainly wouldn’t want to fire it even if you could. It’s kept you alive on more than one occasion already, but even your immune system gets it wrong sometimes. That’s arthritis, and when the immune system thinks the body is threatened and it starts attacking its own tissue. So what is Adalimumab then?

It’s the generic name for Humira, an effective rheumatoid arthritis treatment medication and it’s well known for helping arthritis sufferers have much less of the joint stiffness and pain that is really cutting into their quality of life. And how does Adalimumab work? It blocks the TNF (tumor necrosis factor) protein that the immune system is producing that promotes the swelling in the joint. It’s a darn good thing it is able to do that too, because rheumatoid arthritis has a nasty habit of going after fingers and toes first.

You’ll know what is adalimumab, but surely no one needs to be reminded of how much you get done every day depends on having dexterity with your fingers, and that’s especially true if you’re someone like me who spends workdays typing fastidiously. But in fairness it would be much more debilitating for someone in the trades who needs to work with their hands in more varied capacities. Wouldn’t want to be swinging a hammer at a nail that wasn’t firmly held in place, and you can probably relate to that too.

Walk On

Everyone needs to walk too, and briskly at times. Try to do that with arthritic toes because of rheumatoid arthritis and you’ll quickly see why these people need the help big time. Fortunately, medications like Humira make the grade for that and so the answer to what is Adalimumab can also be that it’s a lifesaver for many people who are doing their best to manage rheumatoid arthritis. And are there arthritic air traffic controllers too? Almost certainly, although relief from pain and stiffness won’t be making them any more on their toes than they already are in a very important job.

Looking more into how does adalimumab work, we can see that it suppressed the inflammatory response behind a number of poor health conditions too. These include:

  • Ulcerative colitis
  • Ankylosing spondylitis
  • Uveitis
  • Psoriatic arthritis

But Humira is primarily indicated for treatment of rheumatoid arthritis, and for people dealing with it they may find that the pain and stiffness is strongest in the morning when they’ve just woken up and haven’t even got started with their day yet. That can play into your mental health too, and that is an indication about how the problem of increasing immobility isn’t always just a physical issue. Another take on what is Adalimumab is that it can be the means to restoring pain-free movement and letting you be productive to the extent you need to be.

Know the Risks

Some people are going to be much more prone to getting rheumatoid arthritis than others, and what people won’t know is that for a lot of them it’s been in the cards since the day they were born. Arthritis can be hereditary, and then there’s the fact that women tend to get it much more than men. Fewer women swinging hammers? Likely fewer questions around what is adalimumab too, but there’s still plenty of occupational activities for ladies where finger dexterity is going to be important too.

Age is a given, and like so many things in life poor health conditions come on more often when you are older. Smoking will increase your risk of this type of arthritis too, and it factors into how does Adalimumab work too because smoking means that the TNF protein is not repressed to the same extent and you get less joint pain relief than you would if you weren’t a dedicated puffer. If you need to quit smoking, there are ways to do that and they don’t put the focus on your willpower – or lack of it.

The last thing about what is adalimumab is for reducing rheumatoid arthritis you should be at a healthy body weight, and for many people that means losing some weight. Carrying too much of it is especially bad when the arthritis is doing a number on your toes, and that’s just simple physics. Gravity exists and weight pushes pressure down. Your fingers won’t absorb any of it, but your toes certainly will. Knees and hips too, but rheumatoid arthritis is less of a factor for those spots.


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IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.