Adlyxin (Lixisenatide)

Adlyxine

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Fact Table

Fact Table
Formula C215H347N61O65S
License FDA approved
Bioavailability N/A (as it is a peptide, it is not bioavailable orally)
Legal status Prescription drug
Chemical Name Lixisenatide
Elimination half-life ~2-3 hours
Dosage (Strength) Injection: 10 mcg and 20 mcg per pen
Pregnancy advice Category C in the United States
Brands Adlyxin, Lyxumia
Protein binding Not applicable (peptide)
PubChem CID 16131404
MedlinePlus N/A
ChEBI N/A
ATC code A10BJ04
DrugBank DB09330
KEGG D09755
Routes of administration Subcutaneous injection

Adlyxin (Lixisenatide) is an injectable prescription medicine designed to improve blood sugar control in adults with type 2 diabetes mellitus. It is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics the actions of the body's natural GLP-1. This medicine is not recommended for the treatment of type 1 diabetes or diabetic ketoacidosis.

Before you buy Adlyxin for the treatment of type 2 diabetes, it is crucial that you talk to your healthcare provider about its potential side effects and Adlyxin cost.

What is type 2 diabetes?

Type 2 diabetes is a persistent health issue where the body either doesn't respond well to insulin or doesn't make enough, causing high blood sugar. It's often signaled by symptoms like thirst, urinating often, and tiredness. Being overweight, inactive, aging, and belonging to specific ethnic groups can increase one's risk. Without proper care, it can lead to severe health problems like heart issues and kidney disorders. It's usually managed with a mix of lifestyle adjustments, medication, and occasionally insulin. Leading a balanced life can help in preventing its development.

Directions

Before using Adlyxin, inspect the solution visually. It should appear clear and colorless.

Adlyxin is started at a lower dose and gradually increased by a healthcare provider based on your body's response.

Adlyxin is administered as a subcutaneous injection, usually into the abdomen, thigh, or upper arm. Change where you inject to avoid skin problems.

Store unused Adlyxin pens in the refrigerator. Once in use, store at room temperature and use within 14 days.

Ingredients

The active ingredient in Adlyxin is Lixisenatide.

Cautions

Do not use Adlyxin if you have a personal or family history of medullary thyroid carcinoma or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Adlyxin is not recommended for patients with gastroparesis.

Monitor blood glucose levels regularly while on Adlyxin.

Inform your healthcare provider if you experience severe and persistent abdominal pain, which may be indicative of pancreatitis.

Many patients have reported experiencing Adlyxin weight loss as a side effect while managing their type 2 diabetes.

Adlyxin should not be used as a first-line therapy for patients who have inadequate glycemic control on diet and exercise alone.

Interactions

When combined with insulin or substances that boost insulin, Adlyxin might lead to low blood sugar levels. Adlyxin can delay the uptake of drugs taken by mouth. It's advisable to consume oral drugs 60 minutes prior to using Adlyxin. Always share with your medical professional the full list of substances you're on, encompassing prescribed, non-prescribed, vitamin, and natural remedies.

Side Effects

Common side effects of Adlyxin include nausea, vomiting, diarrhea, hypoglycemia, headache, dizziness.


Frequently Asked Questions about Adlyxin


Is Adlyxin still available?

Yes, Adlyxin is still available and is prescribed by healthcare providers for adults with type 2 diabetes.


What is Adlyxin used to treat?

Adlyxin is used to improve blood sugar control in adults with type 2 diabetes mellitus.


Does Adlyxin cause weight gain?

Adlyxin does not usually cause weight gain. Some patients may, in fact, experience weight loss while on Adlyxin.


What is the alternative to taking Adlyxin?

There are several other GLP-1 receptor agonists available, such as Trulicity and Victoza. Always consult with your healthcare provider to determine the best treatment option for you.


What are the contraindications for Adlyxin?

Adlyxin is contraindicated in patients with a history of hypersensitivity to lixisenatide or any of its components, and in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.