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Ajovy (fremanezumab-vfrm)

Prescription requiredOnly Available By Prescription
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Ajovy is an injectable prescription medicine used to prevent migraine headaches in adults. Ajovy works by blocking the activity of calcitonin gene-related peptide (CGRP).

Buy Ajovy (fremanezumab-vfrm) online from online Canadian Pharmacy | CanPharm.com

Directions

Use Ajovy injection exactly as it was prescribed. Follow all directions on your prescription label and read all medication guides or instruction sheets. Ajovy is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself. Ajovy is usually given as 1 injection once a month, or as 3 injections (in separate syringes) once every 3 months. Read and carefully follow any Instructions for Use provided with your medicine. Do not use fremanezumab-vfrm if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions. Prepare your injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, is frozen, or has particles in it. Call your pharmacist for new medicine. Store Ajovy in the original carton in a refrigerator, protected from light. Do not freeze or shake this medicine. Take the medicine out of the refrigerator and let it reach room temperature for 30 minutes before injecting your dose. Do not warm the medicine with hot water, sunlight, or a microwave. You may also store Ajovy in the original carton at room temperature for up to 7 days. Throw the medicine away if it has been at room temperature for 7 days or longer Each single-use prefilled autoinjector or syringe is for one use only. Throw it away after one use, even if there is still medicine left inside. Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets. Usual Adult Dose for Migraine Prophylaxis: 225 mg subcutaneously once a month -Alternatively, 675 mg subcutaneously may be administered once every 3 months Comments: -To administer 675 mg subcutaneously, 3 consecutive subcutaneous injections of 225 mg are given. -If switching dosage options, administer the first dose of the new regimen on the next scheduled date of administration.

Ingredients

Each prefilled syringe delivers 1.5 mL of solution containing 225 mg fremanezumab-vfrm, disodium ethylenediaminetetraacetic acid dihydrate (EDTA) (0.204 mg), L-histidine (0.815 mg), L-histidine hydrochloride monohydrate (3.93 mg), polysorbate-80 (0.3 mg), sucrose (99 mg), and Water for Injection, and has a pH of 5.5.

Cautions

You should not use Ajovy if you are allergic to fremanezumab-vfrm. Ajovy is not approved for use by anyone younger than 18 years old. Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having migraines during pregnancy may cause complications such as preeclampsia (which can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby. It may not be safe to breast-feed while using fremanezumab-vfrm. Ask your doctor about any risk.

Side Effects

Get emergency medical help if you have signs of an allergic reaction to Ajovy: hives; difficult breathing; swelling of your face, lips, tongue, or throat. An allergic reaction to fremanezumab-vfrm can occur up to 1 month after an injection. Common Ajovy side effects may include: pain, redness, or a hard lump where the medicine was injected. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.