Auralgan Ear Drops (Antipyrine/Benzocaine/Glycerin)
| Dose | Size & Price | Qty |
|---|
-
Description
-
Reviews (0)
-
Related Products
-
Related Conditions
Fact Table
| Fact Table | |
|---|---|
| Formula | Combination product (Antipyrine: C11H12N2O; Benzocaine: C9H11NO2; Glycerin: C3H8O3) |
| License | FDA-approved legacy otic product (marketed historically; availability varies) |
| Bioavailability | Minimal systemic absorption (otic/topical use) |
| Legal status | Prescription only (Rx) |
| Chemical Name | Antipyrine (1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one); Benzocaine (ethyl 4-aminobenzoate); Glycerol (propane-1,2,3-triol) |
| Elimination half-life | Antipyrine ~12 hours; Benzocaine ~1 hour (systemic data; limited relevance for otic use) |
| Dosage (Strength) | Otic solution: antipyrine 5.4% / benzocaine 1.4% in glycerin; instill 3–4 drops in affected ear every 1–2 hours as needed |
| Pregnancy | Use only if clearly needed; limited data for otic combinations |
| Brands | Auralgan, A/B Otic, generic antipyrine/benzocaine otic solutions |
| Protein binding | Antipyrine ~10%; Benzocaine ~95% (systemic) |
| PubChem CID | Antipyrine: 2206; Benzocaine: 2337; Glycerin: 753 |
| MedlinePlus | Antipyrine and Benzocaine Otic (Drug Information) |
| ChEBI | Antipyrine: 46195; Benzocaine: 27613; Glycerin: 17754 |
| ATC code | N02BB01 (antipyrine); S02DA30 (otic combinations) |
| DrugBank | Antipyrine: DB01435; Benzocaine: DB01086 |
| KEGG | Antipyrine: D00532; Benzocaine: D00092 |
| Routes of administration | Otic (ear drops) |
Auralgan combines antipyrine, benzocaine, and dehydrated glycerin to relieve ear pain and discomfort. Antipyrine is an analgesic that reduces pain and inflammation, while benzocaine acts as a local anesthetic to numb the affected area. The dehydrated glycerin component helps soften earwax, making it easier to remove. This otic solution may be used alongside antibiotics to help manage pain from middle ear infections and can also help with removing excess earwax buildup.
Directions
Auralgan is used only in the ear and should never be taken by mouth.
Before using it, hold the bottle in your hand for 1 to 2 minutes to warm the drops. Lie on your side with the sore ear facing up. Place enough drops into the ear to fill the ear canal. Then soak a small piece of cotton with the drops and gently place it at the ear opening. This can be repeated every 1 to 2 hours until pain or pressure improves.
For earwax buildup, use the drops three times a day for 2 to 3 days to help loosen the wax.
Always wash your hands before and after use. Do not let the dropper touch your ear, fingers, or any surface. Keep the medicine away from the mouth, nose, and eyes, as it can cause burning.
Follow your doctor's instructions, since how often you use it may depend on your condition.
Ingredients
The active ingredients in Auralgan are antipyrine, benzocaine, and glycerin.
Cautions
Before using this medication, you may want to consult a healthcare provider about the following:
- Any existing health conditions
- Any allergies
- A list of all medications currently being taken
Auralgan is meant to be used in the ears only and should never be placed in the eyes.
If you notice burning, redness, itching, swelling, or worsening discomfort after using Auralgan, stop using it and contact a healthcare provider.
Do not let the dropper tip touch your ear, fingers, or any other surface, as this can contaminate the medication and increase the risk of infection.
Auralgan has not been well studied in pregnant women. It should only be used during pregnancy if clearly needed and recommended by a healthcare provider.
It is not known whether Auralgan passes into breast milk. If you are breastfeeding, talk with a healthcare provider before using this medication.
Long-term studies on cancer risk, genetic effects, or fertility have not been conducted with this medication.
Contraindications
Avoid taking or using this medication if any of the following apply:
- Hypersensitivity or allergy to antipyrine, benzocaine, or any other ingredients in the ear drops
- Perforated eardrum or any rupture of the tympanic membrane
- Ear discharge present from the ear canal
Side Effects
Common side effects of Auralgan include:
- Stinging or burning in the ear
- Mild ear pain or discomfort after application
- Redness or irritation around the ear canal
- Temporary itching or sensitivity in the treated ear
These side effects are usually limited to the ear where the drops are applied and often occur shortly after use.
More serious side effects are rare but may include allergic reactions such as rash, itching, hives, or swelling of the face, lips, or tongue.
Seek medical advice if symptoms worsen, do not improve, or signs of an allergic reaction develop.
Frequently Asked Questions about Auralgan Ear Drops
What are Auralgan Ear Drops used for?
Auralgan Ear Drops are used to relieve ear pain, pressure, and discomfort caused by conditions such as middle ear infections or ear inflammation.
What ingredients are in Auralgan Ear Drops?
Auralgan contains antipyrine, a pain reliever; benzocaine, a local anesthetic; and glycerin, which helps soothe and soften the ear canal.
How do Auralgan Ear Drops work?
The drops relieve ear pain by numbing the affected area and reducing discomfort, while glycerin helps keep the ear canal moist.
How should Auralgan Ear Drops be used?
Auralgan is applied directly into the affected ear as directed, usually several times a day, while keeping the head tilted to allow the drops to reach the ear canal.
How quickly do Auralgan Ear Drops relieve pain?
Pain relief often begins within minutes after application, although the duration and degree of relief can vary.
Are Auralgan Ear Drops an antibiotic?
No, Auralgan does not treat infection; it is used only for pain relief and symptom control.
What are the most common side effects of Auralgan Ear Drops?
Side effects are uncommon but may include mild irritation, burning, or stinging in the ear.
Who should not use Auralgan Ear Drops?
Auralgan should not be used if there is a known or suspected perforated eardrum or if there is an allergy to any of its ingredients.
Can Auralgan Ear Drops be used in children?
Auralgan has been used in children for ear pain relief when appropriate, but proper dosing and use should be carefully followed.
What should I do if symptoms do not improve?
If ear pain worsens or does not improve, further medical evaluation may be needed to address the underlying cause.
| Fact Table | |
|---|---|
| Formula | Combination product (Antipyrine: C11H12N2O; Benzocaine: C9H11NO2; Glycerin: C3H8O3) |
| License | FDA-approved legacy otic product (marketed historically; availability varies) |
| Bioavailability | Minimal systemic absorption (otic/topical use) |
| Legal status | Prescription only (Rx) |
| Chemical Name | Antipyrine (1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one); Benzocaine (ethyl 4-aminobenzoate); Glycerol (propane-1,2,3-triol) |
| Elimination half-life | Antipyrine ~12 hours; Benzocaine ~1 hour (systemic data; limited relevance for otic use) |
| Dosage (Strength) | Otic solution: antipyrine 5.4% / benzocaine 1.4% in glycerin; instill 3–4 drops in affected ear every 1–2 hours as needed |
| Pregnancy | Use only if clearly needed; limited data for otic combinations |
| Brands | Auralgan, A/B Otic, generic antipyrine/benzocaine otic solutions |
| Protein binding | Antipyrine ~10%; Benzocaine ~95% (systemic) |
| PubChem CID | Antipyrine: 2206; Benzocaine: 2337; Glycerin: 753 |
| MedlinePlus | Antipyrine and Benzocaine Otic (Drug Information) |
| ChEBI | Antipyrine: 46195; Benzocaine: 27613; Glycerin: 17754 |
| ATC code | N02BB01 (antipyrine); S02DA30 (otic combinations) |
| DrugBank | Antipyrine: DB01435; Benzocaine: DB01086 |
| KEGG | Antipyrine: D00532; Benzocaine: D00092 |
| Routes of administration | Otic (ear drops) |
