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Aygestin (Norethindrone)

Also Known as Utovlan

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Aygestin, also known as Norethindrone Acetate, is a medication primarily used to treat abnormal menstrual periods, endometriosis, and other menstrual disorders. It belongs to a class of medications called progestins, which are synthetic forms of the hormone progesterone. Aygestin works by altering the lining of the uterus, thus regulating the menstrual cycle and reducing symptoms associated with hormonal imbalances.

Before you buy Aygestin, it is crucial that you talk to your healthcare provider about potential side effects and affordability.

Fact Table
Formula C20H26O2
License US FDA (and others)
Bioavailability 64%
Legal status Prescription (Rx)
Chemical Name Norethindrone (Norethisterone)
Elimination half-life 5-10 hours
Dosage (Strength) 5mg tablets (others may exist)
Pregnancy Category X (contraindicated)
Brands Aygestin, others
Protein binding Needs Research*
PubChem CID 6230
MedlinePlus Not Assigned
ATC code G03DC02
DrugBank DB00479
KEGG D00482
Routes of administration Oral

Buy Aygestin (Norethindrone) online from online Canadian Pharmacy |


The Aygestin dosage may vary depending on the condition being treated. It is crucial to follow your doctor's instructions and the prescription label carefully.

Aygestin 5 mg is typically taken orally, with or without food. It is essential to take the medication at the same time each day to maintain consistent levels in the body.

The duration of Aygestin treatment will be determined by your healthcare provider based on your condition and response to the medication. It is essential to complete the full course of treatment as prescribed, even if symptoms improve.

Before starting or discontinuing Aygestin, consult your healthcare provider to discuss any concerns, potential side effects, or drug interactions.


Each Aygestin tablet contains the active ingredient Norethindrone Acetate.


Aygestin should not be used during pregnancy as it may harm the unborn baby. If you become pregnant or suspect pregnancy while taking Aygestin, promptly inform your healthcare provider.

It is not recommended to use Aygestin while breastfeeding, as small amounts of the medication may pass into breast milk and may have undesirable effects on a nursing infant. Consult your healthcare provider before using Aygestin if you are breastfeeding.

Before starting Aygestin, inform your healthcare provider about any medical conditions you have, especially if you have a history of blood clots, stroke, liver disease, breast cancer, or any other hormone-related conditions.

Inform your healthcare provider about any allergies you have, particularly to progestins or any other medications.

Smoking while taking Aygestin may increase the risk of blood clots, stroke, or heart attack. If you smoke, discuss with your healthcare provider how to quit smoking.

Regular check-ups and monitoring of your condition may be necessary while taking Aygestin. Follow-up with your healthcare provider as recommended.


Inform your healthcare provider about all prescription, over the counter, and herbal medications you are taking to avoid potential interactions with Aygestin. Aygestin may interact with certain medications, including but not limited to Anticoagulants (blood thinners) such as warfarin, Anticonvulsants such as phenytoin or carbamazepine, Rifampin, an antibiotic, St. John's Wort, an herbal supplement and Insulin or oral diabetes medications. Limit alcohol consumption while taking Aygestin, as it may increase the risk of certain side effects and interact with the medication.

Side Effects

Common side effects of Aygestin may include:

  • Nausea
  • Headache
  • Breast tenderness
  • Irregular vaginal bleeding or spotting
  • Changes in menstrual flow
  • Mood changes
  • Acne

Frequently Asked Questions about Aygestin (Norethindrone)

What is Aygestin (Norethindrone)?

Aygestin (Norethindrone) is a progestin, which is a synthetic form of the natural sex hormone progesterone.

What is Aygestin (Norethindrone) used for?

It is used for regulating monthly periods, treating endometriosis, and relieving endometriosis-related pain.

How does Aygestin (Norethindrone) work?

It regulates the lining of your uterus (endometrium), which then helps manage your period.

When does Aygestin (Norethindrone) start working?

The time it takes to start working can vary, but it generally begins to have an effect within hours to days of starting treatment.

What are the common side effects of Aygestin (Norethindrone)?

Common side effects include breakthrough bleeding or spotting, change in menstrual flow, lack of periods, headache or migraine, breast enlargement, breast tenderness, nausea, vomiting, stomach cramps or bloating, patches of darkened skin (melasma or chloasma), acne, hair loss, yellowing of the skin or whites of eyes (jaundice), and trouble sleeping (insomnia).

What are the serious side effects of Aygestin (Norethindrone)?

Serious side effects include blood clots, heart attack, changes in vaginal discharge, mood swings, depression, swelling in the hands, feet, or ankles, and changes in weight.

What should I know before taking Aygestin (Norethindrone)?

It’s important to let your physician know if you are pregnant or breastfeeding, have any problems with your liver or kidneys, have heart or blood vessel problems, have ever had a blood clot in an artery or vein, have diabetes, epilepsy, migraine, high blood pressure, or asthma, smoke, are overweight, or have high cholesterol levels.

Is Aygestin (Norethindrone) used for birth control?

Norethindrone acetate (Aygestin) is used for regulating monthly periods and treating endometriosis, whereas norethindrone (Heather) is used for birth control to prevent pregnancy.

Can Aygestin (Norethindrone) be used to treat heavy and painful menstrual periods?

Yes, medium-strength tablets (5 mg) such as Aygestin are used to treat heavy and painful menstrual periods particularly if they are associated with a condition called endometriosis.

Is Aygestin (Norethindrone) a prescription medication?

Yes, Aygestin is a prescription medication.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.