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Brexafemme (Ibrexafungerp)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Brexafemme is a prescription antifungal medication used to treat vaginal yeast infections. It differs from standard yeast infection treatment medications because it is a triterpenoid antifungal, not an azole. It works faster and more effectively to clear vaginal yeast infections for women by blocking glucan synthase, an enzyme in fungal cells critical to their vitality.

Blocking the enzyme's function means the infection can no longer sustain itself, and the woman experiences better relief from vaginal yeast infection symptoms like redness, swelling, rash, irritation, and discharge.

What is Vaginal Yeast Infection?

A vaginal yeast infection is a common condition that happens when there's an overgrowth of yeast in the vagina. Yeast is a fungus that naturally lives in small amounts in our bodies, including the vagina. However, certain factors can cause the yeast to multiply more than usual, leading to an infection. This can happen due to hormonal changes, antibiotics, weakened immune systems, or poor hygiene. The excess yeast can cause symptoms like itching, burning, and a thick, white discharge. It's usually not severe and can be easily treated with prescribed medications.

Fact Table
Formula C44H67N5O4
License US DailyMed
Bioavailability -
Legal status Rx-Only
Chemical Name Ibrexafungerp
Elimination half-life 20 hours
Dosage (Strength) 150mg
Pregnancy No serious adverse effects
Brands Brexafemme
Protein binding More than 99%
PubChem CID 46871657
MedlinePlus a621039
ATC code None
DrugBank DB12471
KEGG D11544
Routes of administration Oral

Buy Brexafemme (Ibrexafungerp) online from online Canadian Pharmacy |


The recommended dosage is to take 2 Brexafemme 150mg tablets twice daily. Take two tablets in the morning and two in the evening, 12 hours apart. Tablets may be taken with or without food.

Always refer to your prescription to confirm the dosage guidelines specified by the physician/pharmacist.


The active ingredient in Brexafemme is Ibrexafungerp.


The use of Brexafemme may not be appropriate for women who are pregnant or breastfeeding. It may also not be suitable for women planning to become pregnant. Discuss with your doctor.


Harmful drug interactions may occur between Brexafemme and other Rx medications, including CY3PA inhibitors or CY3PA inducers like ketoconazole, itraconazole, efavirenz, and etravirine. There are also similar interaction risks between Brexafemme and herbal OTC medications like St. John's Wort. It is best to inform your doctor of your current medications before getting a prescription and buying Brexafemme online.

Side Effects

Most users will not experience Brexafemme side effects, but some may have diarrhea, nausea, abdominal pain, dizziness, or vomiting. If Brexafemme side effects are seen, you may want to stop use and speak with your doctor again to discuss vaginal yeast infection treatment alternatives.

Frequently Asked Questions about Brexafemme

How Long Does Brexafemme Take to Work?

Brexafemme is a medication used for the treatment of vaginal yeast infections. It typically starts working within a few days, improving symptoms such as itching and discharge.

How Long Does Brexafemme Stay in Your System?

The duration of time that Brexafemme stays in your system can vary. After completing the entire treatment, it may take a few days for the medication to be eliminated from your body. However, the duration can vary based on metabolism, kidney function, and dosage.

Can You drink on Brexafemme?

It is generally recommended to avoid consuming alcohol while taking Brexafemme. Alcohol can interfere with the effectiveness of the medication and may also exacerbate specific side effects.

Is Brexafemme Better Than Diflucan?

Whether Brexafemme is better than Diflucan (fluconazole) depends on factors such as your specific condition, medical history, and response to treatment. Both medications commonly treat yeast infections but may have different efficacy rates and potential side effects.

What is the Success Rate of Brexafemme?

The success rate of Brexafemme in treating vaginal yeast infections can be quite high. Clinical studies have shown positive outcomes, with a significant reduction in symptoms and eradication of the infection in many cases.

Can You Buy Brexafemme Over the Counter?

Brexafemme is not available over the counter. It is a prescription medication and can only be obtained with a valid prescription from your doctor or pharmacist.

Is Brexafemme the Same as Fluconazole?

Brexafemme is not the same as fluconazole (brand name: Diflucan). While both medications treat yeast infections, they contain different active ingredients. Brexafemme contains ibrexafungerp, while Diflucan contains fluconazole.

Can I Take Brexafemme and Diflucan Together?

Taking Brexafemme and Diflucan together is only typically recommended if specifically instructed by your doctor or pharmacist. Both medications treat yeast infections, and using them together may not provide additional benefits and could increase the risk of side effects.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.