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Buckley's Mucus and Phlegm Relief (Guaifenesin / Menthol)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Buckley's Mucus and Phlegm Relief offers rapid relief from dry and productive coughs, congestion in the chest, stuffiness in the nose and sinuses, discomfort from a sore throat, elevated body temperature, headaches, and minor aches and pains. It works by loosening and diluting mucus and phlegm. It contains an expectorant to alleviate congestion in the chest.

Fact Table
Formula Guaifenesin: C10H14O4, Menthol: C10H20O
License US FDA, US DailyMed, EU EMA
Bioavailability Unknown
Legal status OTC (Over-the-Counter)
Chemical Name Guaifenesin / Menthol
Elimination half-life About 1 hour
Dosage (Strength) 150mL, 250ml
Pregnancy consult a healthcare provider
Brands Buckley's
Protein binding Negligible
PubChem CID Guaifenesin: 3516, Menthol: 16666
MedlinePlus a682494
ChEBI Guaifenesin: 5379, Menthol: 15409
ATC code Guaifenesin: R05CA03, Menthol: R05CB01 (as a cough suppressant)
DrugBank Guaifenesin: DB00874, Menthol: DB00825
KEGG Guaifenesin: D00347, Menthol: D00064
Routes of administration Oral

Buy Buckley's Mucus and Phlegm Relief (Guaifenesin / Menthol) online from online Canadian Pharmacy |


Shake well before use

Consume every 6 hours as needed

For individuals aged 12 and above: Take 2 to 3 teaspoons (10 to 15 mL)

Refrain from exceeding 4 doses (60 mL) within 24 hours

Not suitable for children under 12

If desired, Buckley's cough syrup for mucus and phlegm can be combined with an equal amount of honey


Active Ingredients

Every teaspoonful (5 mL) of Buckley's cough syrup contains 100 mg of guaifenesin and 10 mg of menthol.

Non-Medicinal Ingredients

Acesulfame K, ammonium carbonate, butylparaben, camphor, Canada balsam, carrageenan, glycerin, pine needle oil, propylene glycol, propylparaben, tincture of capsicum and water.


Avoid exceeding the recommended dosage.

In the event of an accidental overdose, immediately contact a doctor or Poison Control Center, even if no symptoms are present.

Store the medication at room temperature.

Keep out of reach of children.

Do not use it if the sealed carton ends are broken or torn.

If you have an underlying condition that requires prolonged use for more than 7 days, if your cough worsens, persists for over a week, or is accompanied by excessive phlegm (mucus), a high fever, rash, or persistent headache, consult a doctor.

Individuals who have heart, lung, kidney, or liver disease, asthma, advanced age, are pregnant or nursing, or are currently taking other medications should seek medical advice before they buy Buckley's mucus and phlegm.


Combining specific MAO inhibitors with this medication can lead to a potentially dangerous drug interaction. Some products that may interact with this drug include other cough medications and over-the-counter cough/cold products. Rolapitant is also known to interact with this medication. Let your doctor know about all the medications you are taking before you start your treatment with Buckley's Mucus and Phlegm Relief.

Side Effects

Some individuals may experience mild drowsiness, dizziness, nausea, or vomiting. In rare cases, certain individuals may experience severe drowsiness or dizziness even with regular doses. If any of these effects continue or become more severe, it is important to promptly notify your doctor or pharmacist.

Frequently asked questions about Buckley's Cough Syrup

Where can I buy Buckley's cough syrup?

You can purchase Buckley's cough syrup from various online and physical stores. One reliable online source is CanPharm, which offers a variety of healthcare products, including Buckley's cough syrup for mucus and phlegm. Remember to ensure that the retailer is reputable to guarantee the quality of your purchase.

What's in Buckley's cough syrup?

Buckley's cough syrup is a well-known over-the-counter medication designed to alleviate coughs and congestion. It contains several active ingredients including guaifenesin, a powerful expectorant that helps loosen mucus and phlegm from the lungs, and dextromethorphan, a cough suppressant. Other ingredients include ammonium carbonate, Canada balsam, camphor, menthol, pine needle oil, and tincture of capsicum, which together help to soothe the throat and relieve cough symptoms.

Does Buckley's mucus and phlegm work?

Yes, Buckley's mucus and phlegm is designed to be effective in relieving coughs and congestion. The active ingredient, guaifenesin, works by thinning and loosening mucus in the airways, clearing congestion, and making breathing easier. However, the effectiveness can vary among individuals, and it's important to follow the dosage instructions on the package for optimal results.

What is the best medicine for mucus and phlegm?

There are several effective medications for treating mucus and phlegm, and the best one can depend on individual symptoms and health conditions. Buckley's cough syrup for mucus and phlegm is one such medication that is highly regarded for its effectiveness. It contains guaifenesin, which helps to thin and loosen mucus in the lungs, making it easier to cough up and clear the airways.

How long does it take for Buckley's to kick in?

Buckley's cough syrup typically begins to work within 30 minutes to an hour after ingestion. It's important to note that the time it takes to experience relief can vary depending on the severity of the symptoms and individual physiological factors. Always follow the dosage instructions on the package to ensure you're using the medication safely and effectively.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.