Wait, we have a special
offer for you!
Click the button below to get your discount.
Get my coupon now No thanks, I'd like to pay full price
Click the button below to get your discount.
Get my coupon now No thanks, I'd like to pay full price
Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Cetrotide (Cetrorelix) is a synthetic decapeptide with potent gonadotropin-releasing hormone (GnRH) antagonist properties. It plays a critical role in assisted reproductive technologies (ART) by preventing premature ovulation, ensuring that eggs can mature adequately before retrieval. Manufactured through sophisticated biotechnological processes, Cetrotide is designed for subcutaneous injection, offering a convenient administration route for patients undergoing fertility treatments.
The mechanism of action of Cetrotide involves direct competition with natural GnRH for receptor sites in the pituitary gland, leading to a rapid, reversible suppression of gonadotropin secretion. This suppression prevents the LH (luteinizing hormone) surge, which is responsible for triggering ovulation, thereby allowing for the controlled timing of egg maturation and optimizing the conditions for egg retrieval.
Before you buy Cetrotide, it is crucial that you talk to your healthcare provider about potential side effects and Cetrotide cost.
| Fact Table | |
|---|---|
| Formula | C70H92ClN17O14 |
| License | FDA approved |
| Bioavailability | 85% |
| Legal status | Prescription Drugs |
| Chemical Name | Cetrorelix |
| Elimination half-life | 62.8 hours / 3 mg single dose; 5 hours / 0.25 mg single dose; 20.6 hours / 0.25 mg multiple doses |
| Dosage (Strength) | 0.25mg, 3mg |
| Pregnancy | Consult Doctor |
| Brands | Cetrotide |
| Protein binding | 86% |
| PubChem CID | 16130924 |
| MedlinePlus | Not Assigned |
| ChEBI | 59224 |
| ATC code | H01CC02 |
| DrugBank | DB00050 |
| KEGG | D07665 |
| Routes of administration | Subcutaneous injection |
Cetrotide is typically administered during the mid to late phase of the follicular phase of an ovulation induction cycle, but the exact timing and dosage should be determined by a healthcare professional based on individual patient needs and response to treatment.
Ensure that the Cetrotide kit is at room temperature. Use aseptic techniques to mix the provided powder with the sterile water (diluent) included in the kit.
Cetrotide is injected subcutaneously (under the skin), usually in the lower abdominal area. Alternate the injection site daily to minimize skin irritation.
The standard dose is 0.25 mg once daily, but your healthcare provider may adjust this based on your response. Do not adjust the dose or the schedule without consulting your doctor.
Follow the instructions provided in the packaging carefully, and consult your healthcare provider for a demonstration if you are unsure of the proper technique.
Active Ingredient: Cetrorelix acetate.
Cetrotide is contraindicated in patients with known hypersensitivity to cetrorelix acetate or any of the excipients. Before starting treatment, inform your healthcare provider if you have a history of allergic reactions to medications.
Cetrotide is not recommended for use during pregnancy or breastfeeding. Although it is used as part of fertility treatments, its safety during pregnancy has not been established.
Patients with severe renal or hepatic impairment should use Cetrotide with caution, and close monitoring by a healthcare provider is advised.
Cetrotide may interact with other medications, altering their effects or increasing the risk of adverse reactions. Inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking, including over-the-counter medications. Caution should be exercised when using Cetrotide alongside other hormonal treatments, as interactions may affect the efficacy of either medication. Your healthcare provider may need to adjust doses or monitor you more closely for side effects.
Like all medications, Cetrotide injection can cause side effects, although not everyone will experience them. Common side effects include:
Contact your healthcare provider immediately if you experience symptoms of a severe allergic reaction (hives, difficulty breathing, swelling of the face, lips, tongue, or throat) or if you have any signs of OHSS.
What is Cetrotide used for?
Cetrotide is used as part of the hormone treatment for ovarian stimulation during in vitro fertilization (IVF). It blocks the effect of a natural hormone called gonadotropin-releasing hormone (GnRH), which controls the secretion of luteinizing hormone (LH) and starts ovulation during the menstrual cycle.
How do I administer Cetrotide?
Always wash your hands before injecting Cetrotide. Wipe the injection site with an alcohol swab. Use a different area of the body for each dose to prevent discomfort. After injecting, place a cotton ball over the area and apply pressure. Massage the area gently to prevent tenderness. The syringes and needles are for single use only; never reuse them.
What precautions should I take with Cetrotide?
Cetrotide contains mannitol. If you’re allergic to mannitol, your provider may want you to inject the first dose in their office. Proper disposal of used syringes and needles is essential. Talk to your doctor or pharmacist about any health concerns.
Are there serious health risks associated with Cetrotide?
Cetrotide can cause serious health issues, especially for specific groups. Discuss any worries with your doctor or pharmacist and explore other options.
What are the side effects of Cetrotide?
Common side effects include injection site reactions, abdominal pain, and headache. Consult your healthcare provider for personalized advice.
Can I keep prepared Cetrotide for later use?
Prepared Cetrotide should be used immediately. Do not store or reuse ready syringes.
Is Cetrotide available under different brand names?
Yes, Cetrotide is also known as cetrorelix. In the US, it’s sold as Cetrotide; in Canada, it’s marketed as Cetrotide.
What is the dosing schedule for Cetrotide?
Your doctor will provide specific instructions based on your IVF treatment plan. Follow their guidance carefully.
Can I use Cetrotide if I’m allergic to mannitol?
Inform your provider if you have a mannitol allergy. They may take precautions during your injections.
What role does Cetrotide play in IVF treatment?
Cetrotide helps regulate the hormonal response during IVF by blocking GnRH and preventing premature ovulation.
