Cordran Tape (Flurandrenolide)

Prescription Required
Generic
Dose Size & Price Qty
4mcg/sq cm (50cm x 7.5cm)
  • Description
  • Reviews (0)
  • Related Products
  • Related Conditions

Fact Table

Fact Table
Formula C24H33FO6
License FDA approved
Bioavailability Not well defined; systemic absorption depends on skin integrity, occlusion, and duration of use
Legal status Prescription only (Rx)
Chemical Name 6a,9a-difluoro-11ß,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-acetate
Elimination half-life Not specifically established for topical use
Dosage (Strength) 4 micrograms/cm² medicated tape applied once daily (may be changed every 12–24 hours)
Pregnancy Category C – Use only if potential benefit justifies potential risk
Brands Cordran Tape
Protein binding High (typical of corticosteroids; exact percentage not defined)
PubChem CID 5284604
MedlinePlus a601124
ChEBI 50719
ATC code D07AB06
DrugBank DB00591
KEGG D01327
Routes of administration Topical (medicated tape applied to skin)

Cordran Tape is a transparent plastic surgical tape that contains flurandrenolide, a corticosteroid for topical use. Flurandrenolide works by decreasing inflammation and reducing swelling, redness, and itching in the skin. It's used to manage irritation and itching from certain skin problems, especially those that are dry, scaly, and limited to small, specific areas.

Directions

Apply Cordran Tape to clean, dry skin over the affected area. Before applying it, cut the tape to fit the lesion with small scissors. The skin should be clean and dry to ensure the tape sticks properly.

Remove the tape from the package and press it firmly onto the lesion. Smooth down the edges to make sure it adheres well. If the ends of the tape loosen, they can be trimmed off and replaced with fresh tape.

The usual application schedule is to replace the tape every 12 hours for the first 1-2 applications. After that, many patients can leave the tape on for 24 hours at a time.

Some people may keep it on even longer if the tape sticks well and the condition improves. The tape can stay in place during bathing or showering. Pat it dry afterward if it gets wet. Don't pull the tape off roughly, as this may irritate the skin.

Ingredients

The active ingredient in this drug is flurandrenolide.

Cautions

  • Before using this medication, you may want to consult a healthcare provider about the following:
    • Any existing health conditions
    • Any allergies
    • A list of all medications currently being taken
  • Cordran is a topical steroid, and using too much or using it over large areas can allow the medication to be absorbed into the body. This may temporarily affect your adrenal glands, leading to symptoms like weight gain, tiredness, or increased blood sugar.
  • Use Cordran exactly as directed and only on the condition it was prescribed for. Do not cover the treated skin with tight bandages or wraps unless your doctor instructs you to, since this can increase absorption and increase the risk of side effects.
  • If you have a skin infection, you may also need an antifungal or antibacterial medication. Cordran should be paused if the infection doesn't improve quickly.
    Keep the medication away from your eyes and avoid applying it to broken skin unless your doctor says otherwise.
  • Children can absorb more medication through their skin, making them more likely to experience serious steroid-related side effects, including slowed growth. Parents should avoid using tight diapers or plastic pants on treated areas, as they may increase absorption.
  • Cordran should be used with caution during pregnancy or breastfeeding since it's unclear how much absorbs into the body.

Contraindications

Avoid taking or using this medication if any of the following apply:

  • Hypersensitivity to flurandrenolide or any part of the tape
  • The affected skin area is weeping or oozing fluid
  • The affected area is in a skin fold or where skin surfaces rub together, such as under the breasts, in the groin, or armpits

Side Effects

Common side effects of Cordran include:

  • Burning or stinging
  • Itching or irritation
  • Dryness
  • Folliculitis or acne-like bumps
  • Mild skin lightening

These skin-related effects are generally mild and tend to stay at the application site. Some people may also notice increased hair growth or redness in treated areas. Let your healthcare provider know if irritation persists or worsens.

More serious reactions are uncommon but can occur, especially when Cordran is used under occlusive dressings. These may include skin thinning, stretch marks, secondary infections, or significant softening and breakdown of the skin. In rare cases, heat rash or allergic contact dermatitis may develop. Stop using the medication and contact your provider if you notice worsening redness, signs of infection, or significant changes in the texture of your skin.

Frequently Asked Questions about Cordran (Flurandrenolide)


What is Cordran (Flurandrenolide) used for?

Cordran is a topical corticosteroid used to relieve inflammation and itching associated with skin conditions such as eczema, dermatitis, allergies, and rashes. It works by suppressing the immune response that causes inflammation.


How does Flurandrenolide work on the skin?

Flurandrenolide works by reducing the activity of inflammatory chemicals in the skin, such as prostaglandins and leukotrienes. This helps decrease swelling, redness, and itching in affected areas.


What forms does Cordran come in?

Cordran is available in several topical formulations, including ointment, cream, lotion, and a unique tape form (Cordran Tape), which provides continuous delivery of the medication to a specific area.


How should Cordran be applied?

Cordran should be applied in a thin layer to the affected skin area, usually 1 to 3 times daily as directed by a healthcare provider. It should not be used on large body areas or under occlusive dressings unless directed by a doctor.


What are the common side effects of Cordran?

Common side effects may include burning, itching, dryness, irritation, or redness at the application site. These effects are usually mild and temporary. If symptoms worsen, medical attention may be needed.


Can Cordran be used on the face or groin?

Cordran should be used with caution on sensitive areas like the face, groin, or underarms due to the higher risk of thinning skin and other side effects. These areas are more prone to absorbing the steroid.


Is Cordran safe for long-term use?

Long-term use of topical corticosteroids like Cordran can lead to skin thinning, stretch marks, and hormone suppression. It should only be used for extended periods under strict medical supervision.


Can children use Cordran?

Cordran can be used in children, but with caution. Because children's skin absorbs corticosteroids more easily, there is a greater risk of systemic side effects. Pediatric use should be closely monitored by a healthcare provider.


What should be avoided while using Cordran?

Avoid applying Cordran to open wounds, eyes, or mucous membranes. Do not bandage or tightly cover the treated area unless directed. Also, avoid using other topical products on the same site unless approved.


What should I do if I miss a dose of Cordran?

If a dose is missed, apply it as soon as remembered. If it’s almost time for the next dose, skip the missed one. Do not double up or apply extra medication to make up for a missed dose.

No Reviews