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Cosopt PF (Dorzolamide / Timolol)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Cosopt PF is a preservative-free eye solution used to reduce pressure in the eye for people with open-angle glaucoma or ocular hypertension. It combines two active ingredients, Dorzolamide and Timolol, which work together to decrease the production of fluid in the eye, thereby lowering intraocular pressure.

Before you buy Cosopt PF, consult with a healthcare provider to understand the proper usage, potential side effects, and whether it's the most appropriate treatment for your specific condition. To get the best Cosopt PF cost, you can buy them from a Canada or a Canadian Pharmacy.

What is open-angle glaucoma and ocular hypertension?

Open-Angle Glaucoma is a common type of glaucoma where eye drainage canals clog over time, leading to pressure increase and possible vision loss due to optic nerve damage. Ocular Hypertension is a condition with higher-than-normal eye pressure but without signs of glaucoma. This could heighten the likelihood of developing glaucoma.

Fact Table
Formula Dorzolamide: C10H16N2O4S3; Timolol: C13H24N4O3S
License FDA-Approved
Bioavailability Not applicable (topical administration)
Legal status Prescription drug
Chemical Name Dorzolamide / Timolol
Elimination half-life Dorzolamide: ~4 hours; Timolol: ~4 hours
Dosage (Strength) PF 2%-0.5% 0.2m
Pregnancy Consult a doctor
Brands Cosopt PF
Protein binding Dorzolamide: ~33%; Timolol: ~60%
PubChem CID Dorzolamide: 5284549; Timolol: 33624
MedlinePlus a601098 (Cosopt)
ChEBI Dorzolamide: 5284549; Timolol: 9599
ATC code S01ED51 (Combination of dorzolamide and timolol)
DrugBank Dorzolamide: DB00869; Timolol: DB00373
KEGG Dorzolamide: D00652; Timolol: D08600
Routes of administration Topical

Buy Cosopt PF (Dorzolamide / Timolol) online from online Canadian Pharmacy |


Cosopt PF is typically used as an eye drop and is administered directly into the affected eye(s). The usual recommended dose is one drop into the affected eye(s) two times per day.

Here are general directions for using eye drops:

  • Wash your hands before handling Cosopt PF eye drops.
  • Tilt your head back slightly.
  • Position the dropper over your eye and gently squeeze to release a drop into the pocket created by pulling down your lower eyelid.
  • Close your eye and press your finger to the inside corner of your eye for about 1-2 minutes.
  • Do not rinse the dropper or touch the dropper tip to any surface to avoid contamination.

Avoid touching the dropper to your eye or any other surface to maintain sterility and prevent possible infection.

Consistent use of this medication is key to maximize its benefits. If you are using another type of eye medication, wait at least 10 minutes before applying other medications.


Cosopt PF contains two active ingredients: Dorzolamide Hydrochloride and Timolol Maleate.


Inform your doctor if you have ever had an allergic reaction to dorzolamide, timolol, or any other ingredients in Cosopt PF.

Certain medical conditions can be affected by Cosopt PF, including heart conditions, lung diseases like asthma or COPD (Chronic Obstructive Pulmonary Disease), diabetes, or thyroid disorders. Make sure to always share your health background with your healthcare provider.

Cosopt PF should only be used during pregnancy or while breastfeeding if clearly needed. Have a conversation with your healthcare provider about the potential advantages and risks.

Remove contact lenses before applying Cosopt PF. You can reinsert them 15 minutes after administration.

Do not use Cosopt PF if it changes colors or becomes cloudy, or if you have an eye infection or injury.


Some medications that may interact with this drug include high doses of aspirin or related salicylates, propranolol, acetazolamide, methazolamide, clonidine, fluoxetine, digoxin, epinephrine, methyldopa, or quinidine.

Side Effects

Cosopt PF can cause side effects like blurred vision, unusual taste in your mouth, eye discomfort, dry eyes, and light sensitivity. Less common but serious effects include allergic reactions, slow or irregular heartbeat, muscle weakness, mood changes, breathing trouble, and cold hands or feet. Not everyone will experience these. Always contact your healthcare provider immediately if you notice any adverse effects.

Frequently Asked Questions about Cosopt

How long can you use Cosopt?

The duration for using Cosopt depends on your doctor's advice, your medical condition, and how your body responds. Use it regularly and at the same time each day for best results. Don't stop without consulting your doctor.

How long do Cosopt eye drops last?

The duration of a bottle of Cosopt lasts depends on the bottle size and usage frequency. The medication is usually applied twice daily, with each dose controlling eye pressure for about 12 hours. Once opened, a bottle typically should be used within 28 days to avoid contamination.

How much does Cosopt lower eye pressure?

Cosopt, used for certain types of glaucoma or ocular hypertension, can typically reduce intraocular pressure (IOP) by about 20-30% from baseline levels. However, the effectiveness varies among individuals.

Does Cosopt affect blood pressure?

Cosopt eye drops containing timolol, a beta-blocker, can potentially lower blood pressure. Let your healthcare provider know about your past health conditions and any medications you're currently taking. They will monitor your blood pressure during treatment.

Does Cosopt affect the heart?

Cosopt eye drops have timolol, a beta-blocker that can impact the heart's functioning. Inform your healthcare provider about your medical history and heart conditions. They will monitor your heart during treatment and advise seeking immediate medical attention if any worrisome heart-related symptoms occur.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.