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Credelio Plus (Lotilaner+Milbemycin Oxime)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Credelio® Plus is an antiparasitic veterinary medicinal product containing a minimum dose of 20 mg/kg lotilaner and 0.75 mg/kg milbemycin oxime as active substances, which belong to the isoxazoline and macrocyclic lactones class of parasiticides, respectively. Credelio® Plus is administered monthly as an oral chewable tablet to dogs with, or at risk from, mixed infestations/infections of ticks, fleas, gastrointestinal nematodes, heartworm and/or lungworm.

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Side Effects

Weight loss Elevated blood urea nitrogen (BUN) Increased urination Diarrhea