Daliresp (Roflumilast)

Daxas

Prescription Required
Brand
Dose Size & Price Qty
250mcg
500mcg
Generic
Dose Size & Price Qty
500mcg
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Fact Table

Fact Table
Formula C17H14Cl2F2N2O3
License FDA approved
Bioavailability ~80%
Legal status Prescription only
Chemical Name 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Elimination half-life 17-30 hours (roflumilast), 27-30 hours (active metabolite roflumilast N-oxide)
Dosage (Strength) 250 mcg, 500 mcg
Pregnancy Consult Doctor (Pregnancy Category C in the U.S.)
Brands Daliresp, Daxas
Protein binding 99%
PubChem CID 5284373
MedlinePlus a611037
ChEBI 68886
ATC code R03DX07
DrugBank DB01656
KEGG D01896
Routes of administration By mouth

Daliresp is a COPD treatment medication used to relieve the breathing difficulties people have with COPD attacks, plus making it so they have fewer of those attacks. It is usually prescribed for people with severe COPD. Daliresp uses may also be to treat bronchitis. Roflumilast is a PDE-4 oral selective phosphodiesterase inhibitor, and it works to limit the inflammation response that causes constriction of the airway. You can buy Daliresp with a prescription here at Canpharm.

Directions

Standard dosage for Daliresp is to take the medication 1x daily and with or without food. It is best to take it at the same time every day.

Ingredients

The active ingredient in Daliresp is Roflumilast

Cautions

Let your doctor know of any history of liver disease, cancer, heart disease, tuberculosis, herpes, or immune system disorders like HIV or Lupus before starting on Daliresp

This medication may make you dizzy or drowsy, and it may be advisable to avoid driving or using machinery while taking Daliresp generic

Keep at room temperature and without exposure to light or moisture

Be aware of medication expiry date

Interactions

Negative drug interactions may occur between Daliresp and other Rx or OTC medications, including albuterol, alprazolam, amlodipine, aspirin, atorvastatin, azithromycin, furosemide, gabapentin, levothyroxine, lisinopril, losartan, metformin, metoprolol, montelukast, guaifenesin, omeprazole, pantoprazole, prednisone, tiotropium, budesonide, formoterol, and tramadol. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Daliresp online.

Side Effects

Daliresp side effects may occur, and some users may experience diarrhea, stomach or abdominal pain, nausea, headache, dizziness or weight loss. Some people using PDE-4 medications may also find they negatively affect their sleep. If side effect are seen you may want to discontinue use and meet with a doctor again to discuss COPD treatment medication alternatives.

Frequently Asked Questions about Daliresp


What is Daliresp used for?

Daliresp (roflumilast) is used to reduce the risk of COPD (chronic obstructive pulmonary disease) exacerbations in patients with severe COPD and chronic bronchitis.


How does Daliresp work?

Daliresp works by inhibiting an enzyme called phosphodiesterase-4 (PDE4), which helps reduce inflammation in the airways and lungs.


What happens if you stop taking Daliresp?

Stopping Daliresp may increase the risk of COPD exacerbations and a return of symptoms. Consult your doctor before discontinuing.


How long does it take for Daliresp to start working?

Daliresp may take several weeks to show noticeable improvement in COPD symptoms, though the full effect might be seen after a few months.


Can you just stop taking Daliresp?

It is not recommended to stop taking Daliresp abruptly without consulting your doctor, as it could lead to worsening symptoms.


How to stop taking Daliresp?

To stop taking Daliresp, consult your doctor for a safe discontinuation plan tailored to your health condition.


How long does Daliresp stay in your system?

The half-life of Daliresp is about 17 hours, meaning it may take roughly 3–4 days to be mostly eliminated from your system.


Is Daliresp safe?

Daliresp is generally safe when used as prescribed, but it may not be suitable for people with certain conditions, such as liver disease or depression. Always discuss risks with your doctor.


What are the side effects of Daliresp?

Common side effects include diarrhea, weight loss, nausea, headache, insomnia, and back pain. Rare but serious side effects include mental health changes or allergic reactions.


How long do side effects of Daliresp last?

Side effects may last as long as the medication is in your system. Mild side effects often improve as your body adjusts, while serious side effects should be reported to your doctor immediately.

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