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Elonox (Enoxaparin)

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The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Description

Elonox, containing the active ingredient enoxaparin, is a low molecular weight heparin (LMWH) used predominantly for the prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). It is also commonly prescribed for patients undergoing certain types of surgery to prevent blood clots and is used in the treatment of acute coronary syndrome (ACS), including heart attacks and unstable angina.

Enoxaparin works by inhibiting specific clotting factors in the blood, notably Factor Xa and IIa, which plays a crucial role in the blood clotting process. This action helps reduce the ability of blood to form clots. Unlike traditional heparin, enoxaparin has a more predictable response and does not typically require monitoring of blood clotting times, making it convenient for patient use in a non-hospital setting.

Before you buy Enoxaparin injection, it is crucial that you talk to your healthcare provider about potential side effects and Enoxaparin cost.

Fact Table
Formula C26H40N2O36S5
License FDA approved
Bioavailability 100% (Subcutaneous)
Legal status Prescription Drugs
Chemical Name Enoxaparin sodium
Elimination half-life 4.5 hours (Subcutaneous)
Dosage (Strength) 30 mg/0.3 mL, 40 mg/0.4 mL, 60 mg/0.6 mL
Pregnancy Category B (Considered safe, but consult your doctor)
Brands Lovenox, Clexane
Protein binding < 10%
PubChem CID 106040
MedlinePlus a601210
ChEBI 9127
ATC code B01AB05
DrugBank DB01225
KEGG D03696
Routes of administration Subcutaneous

Buy Elonox (Enoxaparin) online from online Canadian Pharmacy | CanPharm.com

Directions

Elonox is administered via subcutaneous injection. It is crucial to follow your healthcare provider's instructions precisely.

For DVT Prophylaxis: Typically, 40 mg is administered once daily via subcutaneous injection. The duration of treatment may vary depending on the patient's risk factors and the type of surgery undergone.

For Treatment of Acute DVT or PE: The usual dose is 1 mg/kg administered twice daily or 1.5 mg/kg once daily by subcutaneous injection. Treatment duration is generally at least five days and until adequate anticoagulation is established.

For Acute Coronary Syndrome: For patients with unstable angina or non-Q-wave myocardial infarction, the recommended dose is 1 mg/kg administered subcutaneously every 12 hours in combination with oral antiplatelet therapy.

Always ensure the injection sites are rotated to avoid skin irritation, and do not inject into muscle tissue.

Ingredients

Active Ingredient: Enoxaparin sodium.

Cautions

Elonox should be used with caution in patients with known allergies to heparin or pork products, as it may cause hypersensitivity reactions. Patients with kidney impairment, low body weight, or those at increased risk for bleeding should consult their healthcare provider as dose adjustments may be necessary.

Do not use enoxaparin sodium injection if you have:

Major bleeding

Thrombocytopenia (low platelet count) induced by heparin

An uncontrolled high blood pressure

Recent or upcoming surgery of the brain, spinal cord, or eye

Interactions

Elonox can interact with various medications and increase the risk of bleeding. Therefore, it is crucial to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and herbal supplements. Key interactions include antiplatelet agents (e.g., aspirin, clopidogrel), nonsteroidal anti-inflammatory drugs (NSAIDs), other anticoagulants (e.g., warfarin, dabigatran) and selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs).

Side Effects

Common side effects of Elonox include:

  • Mild irritation, pain, or bruising at the injection site
  • Bleeding
  • Anemia

Frequently Asked Questions about Elonox (Enoxaparin)


What is Elonox?

Elonox, also known as Elonox HP, is a biosimilar biologic drug to Lovenox HP. It’s used to treat acute ST-segment Elevation Myocardial Infarction (STEMI), a particular form of heart attack.


What class of drug is enoxaparin?

Enoxaparin belongs to the class of medicines known as low molecular weight heparins (LMWH) and is an anticoagulant.


How to inject Elonox?

Elonox is administered by subcutaneous injection. The recommended dose is 1 mg/kg every 12 hours. Always choose a different injection site for each dose.


Why is enoxaparin a high-risk medication?

Enoxaparin can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), leading to long-term or permanent paralysis.


What is the most common side effect of enoxaparin?

The most common side effects of enoxaparin include bleeding, anemia, pain and bruising at the injection site, fever, and swelling in the legs.


What drugs should not be taken with enoxaparin?

Drugs that increase the risk of bleeding, such as NSAIDs (ibuprofen, Advil, Aleve, and others), should not be taken with enoxaparin.


How many days do you take enoxaparin for?

Enoxaparin is usually taken for at least 5 days and until a therapeutic oral anticoagulant effect has been achieved. The average duration is 7 days.


When should you not take enoxaparin?

You should not use enoxaparin if you are allergic to it, heparin, benzyl alcohol, or pork products, or if you have active or uncontrolled bleeding.


Does enoxaparin work immediately?

Yes, enoxaparin has an immediate onset of action.


What organ does enoxaparin affect?

Enoxaparin primarily affects the blood, preventing the formation of blood clots. It doesn’t specifically target an organ, but its effects are crucial for the heart and lungs.


Do you keep enoxaparin in the fridge?

The storage instructions for enoxaparin (Elonox) should be provided by the pharmacist or mentioned in the medication guide. Please refer to those instructions for accurate information.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.