A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Fasenra is a monoclonal antibody that affects the actions of the body's immune system. Benralizumab works by reducing levels of eosinophils, a certain type of white blood cell that may contribute to the symptoms of asthma. Fasenra injection is a prescription medicine used together with other asthma medicines to help control severe asthma in adults and children who are at least 12 years old. Fasenra is for people whose asthma is not well controlled with other medications.
Before you start treatment with Fasenra, your doctor may perform tests to measure your eosinophil levels. Fasenra is injected under your skin (subcutaneously) one time every 4 weeks for the first 3 doses, and then every 8 weeks. Fasenra comes in a single dose prefilled syringe and in a single dose autoinjector. A healthcare provider will inject Fasenra using the single-dose prefilled syringe. If your healthcare provider decides that you or a caregiver can give the injection of Fasenra, you or your caregiver should receive training on the right way to prepare and give the injection using the Fasenra Pen autoinjector. Follow your doctor's dosing instructions very carefully. If you've been using a steroid medication, do not stop using it unless your doctor tells you to. Fasenra is not a rescue medicine for asthma attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your fast-acting medicine does not work. You may need frequent medical tests to help your doctor determine how long to treat you with Fasenra. Asthma is often treated with a combination of drugs. Use all medications as directed and read all medication guides. Do not change your dose or dosing schedule without your doctor's advice. Your dose needs may change due to surgery, illness, stress, or a recent asthma attack. Tell your doctor if any of your medicines seem to stop working.
Medicinal ingredient: benralizumab Non-medicinal ingredients: L-histidine, L-histidine hydrochloride monohydrate, a,a-trehalose dihydrate, polysorbate 20 and water.
Before you receive Fasenra, tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breast-feeding.
Get emergency medical help if you have signs of an allergic reaction to Fasenra: hives, rash; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: new or worsening asthma symptoms. Common Fasenra side effects may include: sore throat; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.