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Inclunox (Enoxaparin)

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Description

Inclunox, with its active ingredient Enoxaparin, is a low molecular weight heparin (LMWH) primarily used in the prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). This anticoagulant medication is effective in reducing the ability of blood to clot. Enoxaparin is also employed in the management of acute coronary syndrome, including unstable angina and non-Q-wave myocardial infarction. Packaged as a pre-filled syringe, Inclunox is administered subcutaneously to ensure a steady absorption and consistent therapeutic levels.

Before you buy Inclunox, it is crucial that you talk to your healthcare provider about potential side effects and Enoxaparin price.

Fact Table
Formula C26H40N2O36S5 (average molecular structure)
License FDA approved
Bioavailability Subcutaneous: ~92%
Legal status Prescription Drugs
Chemical Name Enoxaparin sodium
Elimination half-life 4.5 hours (subcutaneous)
Dosage (Strength) Various, ranging from 30 mg to 150 mg prefilled syringes
Pregnancy Consult a healthcare provider
Brands Inclunox, Lovenox
Protein binding Low (<10%)
PubChem CID 108622 (for enoxaparin sodium)
MedlinePlus a601210
ChEBI 63598 (Enoxaparin sodium)
ATC code B01AB05
DrugBank DB01225 (Enoxaparin sodium)
KEGG D07941 (Enoxaparin sodium)
Routes of administration Subcutaneous

Buy Inclunox (Enoxaparin) online from online Canadian Pharmacy | CanPharm.com

Directions

Inclunox is intended for subcutaneous injection and should not be administered intramuscularly due to the risk of hematoma formation. Patients or caregivers should be trained by healthcare professionals on the proper technique to ensure safe administration. Take Enoxaparin dose exactly as prescribed by your healthcare provider. Continue to take Inclunox even if you feel well, unless advised otherwise by your doctor.

Ingredients

The active ingredient in Inclunox is Enoxaparin sodium.

Cautions

Inclunox should be used with caution in patients with known hypersensitivity to heparin or pork products, as Enoxaparin is derived from porcine intestinal mucosa. Patients with active major bleeding, thrombocytopenia, or those who are undergoing spinal anesthesia or lumbar puncture should avoid using this medication due to the increased risk of spinal or epidural hematoma, which can lead to long-term or permanent paralysis.

Renal impairment significantly affects the clearance of Enoxaparin, and dose adjustments may be necessary to prevent bleeding complications. Regular monitoring of kidney function and platelet counts is advised.

Interactions

Enoxaparin can interact with various drugs, increasing the risk of bleeding especially when used with antiplatelet agents (e.g., aspirin, clopidogrel), nonsteroidal anti-inflammatory drugs (NSAIDs) and other anticoagulants (e.g., warfarin, dabigatran). Consultation with a healthcare provider is essential before starting any new medications, including over-the-counter drugs and herbal supplements, to ensure they do not interact with Inclunox.

Side Effects

Common side effects of Inclunox include:

  • Bleeding complications, which may range from minor local site bruising to major bleeding
  • Pain, irritation, or redness at the injection site
  • Anemia
  • Thrombocytopenia (low platelet count)

Frequently Asked Questions about Inclunox


What is Inclunox?

Inclunox is a brand of enoxaparin, which is a type of anticoagulant medication. It is used to prevent and treat blood clots in the veins, including deep vein thrombosis (DVT) and pulmonary embolism (PE). It is also used to prevent complications in patients with certain types of heart conditions, such as unstable angina or non-Q-wave myocardial infarction.


How does Inclunox work?

Inclunox works by inhibiting certain proteins in the blood that are responsible for blood clotting. It enhances the activity of antithrombin III, which in turn inhibits the activity of factor Xa and thrombin, key components in the coagulation process. This helps prevent the formation of harmful clots in the blood vessels.


How is Inclunox administered?

Inclunox is typically administered as an injection under the skin (subcutaneously). It is often given in the abdomen area but can also be injected into other areas with a layer of fat, such as the thigh. The exact dosage and frequency depend on the medical condition being treated and the patient's specific circumstances.


What are the common side effects of Inclunox?

Common side effects of Inclunox include mild pain, redness, or irritation at the injection site. Some patients may also experience bleeding or bruising more easily, nosebleeds, and bleeding gums. If you notice any severe or unusual side effects, you should contact your healthcare provider immediately.


Who should not use Inclunox?

Inclunox should not be used by individuals with known hypersensitivity to enoxaparin or heparin, those with active major bleeding, or those with conditions such as heparin-induced thrombocytopenia (HIT). It is also contraindicated in patients with certain medical conditions that increase the risk of bleeding.


Can Inclunox be used during pregnancy?

Inclunox is sometimes used during pregnancy to prevent and treat blood clots, as it does not cross the placenta and is considered safer than some other anticoagulants. However, its use should be closely monitored by a healthcare provider to ensure the safety of both the mother and the developing baby.


What should I do if I miss a dose of Inclunox?

If you miss a dose of Inclunox, you should take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one. Consult your healthcare provider if you have any concerns.


Are there any dietary restrictions while using Inclunox?

While using Inclunox, it is generally advised to maintain a consistent diet. However, you should avoid excessive consumption of foods rich in vitamin K (such as leafy green vegetables) as they can interfere with anticoagulation. Always discuss any dietary changes with your healthcare provider.


Can Inclunox interact with other medications?

Yes, Inclunox can interact with other medications, including other anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain supplements. These interactions can increase the risk of bleeding. It is important to inform your healthcare provider about all medications and supplements you are taking.


How should Inclunox be stored?

Inclunox should be stored at room temperature, away from direct light and moisture. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the solution is discolored or contains particles. Dispose of it properly according to the guidelines provided by your healthcare provider or pharmacist.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.