Incruse Ellipta (Umeclidinium)

Incruse Ellipta (umeclidinium) is a daily inhaler used to treat chronic obstructive pulmonary disease (COPD) in adults. It helps by relaxing the muscles around the airways, making it easier to breathe. The medication is used to manage ongoing symptoms such as shortness of breath and wheezing in people with chronic bronchitis or emphysema. It is not meant for quick relief during sudden breathing attacks but for long-term control. With regular use, Incruse Ellipta can help improve breathing and reduce COPD flare-ups.

Directions

Incruse Ellipta is used by mouth through the inhaler device. The standard dosage is 62.5 mcg (micrograms) of umeclidinium given as 1 inhalation once daily. Use it at the same time every day.

After removing the inhaler from the sealed tray, discard the tray and use the medication within 6 weeks. The dose counter on the device shows how many doses remain, and when the counter reads "0," the inhaler is empty even if it doesn't feel completely empty.

Ingredients

Incruse Ellipta contains umeclidinium as its active ingredient.

Cautions

• Before using this medication, you may want to consult a healthcare provider about the following:
  • Any existing health conditions
  • Any allergies
  • A list of all medications currently being taken
• Incruse Ellipta is for daily COPD maintenance, not for sudden breathing attacks. If your symptoms get worse quickly, don't start or rely on Incruse. Use a rescue inhaler (like albuterol) and get medical help.
• If Incruse stops controlling your COPD, your rescue inhaler isn't working as well, or you need your rescue inhaler more often than usual, contact your provider right away. Don't take extra Incruse doses.
• Rarely, inhalers can cause paradoxical bronchospasm, meaning your breathing suddenly gets worse right after a dose; if this happens, use a rescue inhaler immediately, stop Incruse, and get medical care.
• Serious allergic reactions can happen (hives, rash, itching, swelling of the face/lips/tongue/throat, trouble breathing); stop Incruse and get emergency help if these occur.
• If you have a severe milk protein allergy, you should not use Incruse Ellipta (some dry powder inhalers contain lactose that can trigger reactions in sensitive people).
• If you have narrow-angle glaucoma, watch for eye pain, blurred vision, or seeing halos/colors with red eyes. Seek medical attention if these show up.
• If you have trouble urinating or have prostate/bladder outlet problems, Incruse can worsen urinary retention. Call your clinician if you notice difficulty peeing or painful urination.

Contraindications

Avoid taking or using this medication if any of the following apply:

• Severe hypersensitivity to milk proteins
• Hypersensitivity to umeclidinium
• Allergic reactions to any of the ingredients in Incruse Ellipta

Side Effects

Common side effects of Incruse Ellipta include:

• Upper respiratory tract infection
• Stuffy or runny nose
• Cough
• Mouth or throat pain
• Muscle or joint pain
• Stomach pain
• Tooth pain
• Bruising or darkened areas of skin
• Change in taste
• Fast or irregular heartbeat

These effects are usually mild, but let your healthcare provider know if they persist or become bothersome.

More serious side effects can occur and may need immediate medical attention. These include sudden breathing problems right after inhalation, severe allergic reactions, new or worsening eye problems such as acute narrow-angle glaucoma, and urinary retention. Call your healthcare provider or seek emergency care if you develop trouble breathing, facial or throat swelling, eye pain or vision changes, or trouble urinating.