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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Invokana contains the active substance canagliflozin which belongs to a group of medicines called “blood-glucose lowering drugs” used by adults to treat type 2 diabetes.
The starting dose of Invokana is one 100 mg tablet each day. Your doctor will decide whether to increase your dose to 300 mg.
Your doctor may limit your dose to 100 mg if you have a kidney problem.
Your doctor will prescribe the strength that is right for you.
Swallow the tablet whole with a half glass of water.
You can take your tablet with or without food. It is best to take your tablet before the first meal of the day.
Try to take it at the same time each day.
The active substance is canagliflozin. The other ingredients are: - tablet core: croscarmellose sodium, hydroxypropyl cellulose, lactose anhydrous, magnesium stearate, and microcrystalline cellulose - film-coating: macrogol (3350), polyvinyl alcohol, talc, and titanium dioxide (E171). The 100 mg tablet also contains iron oxide yellow (E172).
Do not use Invokana if you have Type 1 Diabetes, diabetic ketoacidosis, severe kidney problems, severe liver problems,serious heart disease or stroke, low blood pressure or taking anti-hypertensives. Talk to doctor or pharmacist if any of these conditions are present. Invokana is not recommended for children & adolescents under 18 years. Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Invokana should not be used during pregnancy
Stop taking Invokana and see a doctor as soon as possible if you have any of the following serious side effects:
1. Dehydration (Symptoms include dizziness, dry mouth, weak, fast heartbeat.
2. Hypoglycaemia (Symptoms include blurred vision, sweating, tingling lips, trembling & feeling anxious.
Other side effects:
• vaginal yeast infection.
Common (may affect up to 1 in 10 people)
• rash or redness of the penis or foreskin (yeast infection)
• urinary tract infections
• changes in urination (including urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night)
• feeling thirsty
• blood tests may show changes in blood fat (cholesterol) levels and increases in amount of red blood cells in your blood (haematocrit).
• rash or red skin – this may be itchy and include raised bumps, oozing fluid or blisters
• blood tests may show changes related to kidney function (creatinine or urea) or potassium
• blood tests may show increases in your blood phosphate level
• bone fracture