Janumet XR (Sitagliptin/Metformin)

JANUMET XR Tablets contain two oral antidiabetic medications used in the management of type 2 diabetes: sitagliptin and metformin hydrochloride extended-release

Directions

JANUMET XR should be administered with food to reduce the gastrointestinal side effects associated with the metformin component. JANUMET XR should be given once daily with a meal preferably in the evening. JANUMET XR should be swallowed whole. The tablets must not be split, crushed, or chewed before swallowing.
The 100 mg sitagliptin/1000 mg metformin hydrochloride extended-release tablet should be taken as a single tablet once daily. Patients using two JANUMET XR tablets (such as two 50 mg sitagliptin/500 mg metformin hydrochloride extended-release tablets or two 50 mg sitagliptin/1000 mg metformin hydrochloride extended-release tablets) should take the two tablets together once daily.
Follow the directions for using this medicine provided by your doctor. This medicine may come with a patient information leaflet. Read it carefully. Ask your physician, nurse, or pharmacist any questions that you may have about this medicine.

Ingredients

sitagliptin and metformin HCl, Extended-Release Tablets

Side Effects

Some common side effects of this drug are:

• Nausea
• Vomiting
• Upset stomach
• Diarrhoea
• Headache
• Metallic taste in the mouth

Some serious but rare side effects of this drug include:

• Join pain
• Change in the amount of urine
• Unusual skin blisters
• Shortness of breath
• Swelling of ankles and feet
• Unusual tiredness
• Sudden weight gain

If you experience any of these side effects, notify your doctor immediately.