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Lumakras (Sotorasib)

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Lumakras is a lung cancer treatment medication available by prescription and used specifically to treat non-small cell lung cancer in adults. Lumakras is prescribed when the cancer is either locally advanced or metastatic or systemic therapy has been insufficient for the patient. Sotorasib is and RAS GTPase inhibitor class drug that works by disabling the G12c mutation in the K-Ras protein, one that aids the growth of cells in your body and is used similarly by cancerous cells. Buy Lumakras from Canada and Canpharm and get the best Lumakras price.

What is Lung Cancer?

Lung cancer is a disease caused by uncontrolled cell division in your lungs with cancers that usually start in the bronchioles or alveoli of your lungs. When the cells divide to this extent, they cause tissue to mass and become tumors. The tumors then remain in the lungs and gradually start to make the organs fail or spread outside the lungs into other organs of the body (metastasize). Lung cancer is the 3rd most common type of lung cancer in North America.

Fact Table
Formula C29H32F3N7O2
License FDA approved in May 2021
Bioavailability Not explicitly stated; metabolism primarily via CYP3A4
Legal Status Prescription only
Chemical Name Sotorasib
Elimination Half-Life 5.5 hours
Dosage (Strength) 120 mg tablets
Pregnancy Advice No adequate and well-controlled studies in pregnant women; use only if the potential benefit justifies the potential risk to the fetus
Brands Lumakras
Protein Binding 93-99%
PubChem CID 155036272
MedlinePlus Number Not listed
ChEBI ID Not available
ATC Code L01EX19
DrugBank ID DB15660
KEGG ID D11938
Routes of Administration Oral

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Standard Lumakras dose for non-small cell cancer treatment is 960mg 1x per day taken orally with or without food. Take tablet whole with water and do not chew or crush. Dosage may vary based on patient condition and current response to treatment. Always take your medication exactly as indicated in your prescription.


The active Ingredients is Sotorasib.


Let your doctor know of any history of liver disease, hepatitis, pneumonitis, or interstitial lung disease before starting on Lumakras

Liver function, blood, and protein urine tests may be required before you start on this medication. Taking Lumakras may lead to liver damage as a side effect.

Women who are pregnant or breastfeeding should not use Lumakras unless approved to do so by their doctor

Eating high fat or high protein meals may increase the risk of Lumakras side effects

Store medication at room temperature from 68 to 77 degrees Fahrenheit


Negative drug interactions may occur between Lumakras and other Rx medications, including nizatidine, famotidine, pantoprazole, omeprazole, lansoprazole, midazolam and other benzodiazepines, rifadin and other antibiotics, and cardiac glycosides used for heart conditions like digoxin. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Lumakras online.

Side Effects

Lumakras side effects may occur, and some users may experience abdominal pain, constipation, cough, appetite loss, fatigue, nausea, vomiting, muscle or joint pain, diarrhea, skin rash, or swelling in other areas of the body. If side effects are experienced, you may want to stop use and meet with your doctor again to discuss lung cancer treatment medication alternatives.

Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit or call 1-800-FDA-1088

Frequently Asked Questions about Lumakras

Is Lumakras chemotherapy?

No, Lumakras is a prescription medication, but it is used in conjunction with chemotherapy as part of a lung cancer treatment regimen.

How does Lumakras work?

Lumakras slows the growth and expansion of cancerous cells by targeting the G12c mutation in a protein that is involved in cell growth throughout the body.

How long do you take Lumakras?

The duration of your use of this medication will be determined by your doctor based on your response to treatment with it.

When was Lumakras approved?

Lumakras was approved by the US FDA in May of 2021.

Where to buy Lumakras?

A prescription for Lumakras can be filled at any storefront or online pharmacy.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.