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Neupogen (Filgrastim)

Prescription requiredOnly Available By Prescription
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Neupogen is a febrile neutropenia prevention medication available by prescription and prescribed for people who are in chemotherapy treatments and have low white blood cell counts. Filgrastim is a G-CSF class drug that works by stimulating bone marrow so that white blood cell production is increased and the cells mature faster into neutrophils that then go into the bloodstream to fight bacteria and reduce the risk of neutropenia infection during cancer treatment. Buy Neupogen from Canada and CanPharm and get the best price on it.

Fact Table
Formula C845H1343N223O243S9
License US FDA, US DailyMed, EU EMA
Bioavailability 60 to 70%
Legal status Prescription drug
Chemical Name Filgrastim
Elimination half-life 3.5 hours
Dosage (Strength) 300mcg/mL, 480mcg/1.6mL
Pregnancy Consult a doctor
Brands Neupogen
Protein binding Unknown
PubChem CID Not available because this is not a discrete structure
MedlinePlus a692033
ChEBI Not Assigned
ATC code L03AA02
DrugBank DB00099
KEGG D03235
Routes of administration Intraveneous, subcutaneous

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The Neupogen injection should be administered subcutaneously (under skin) daily and at the same time each day during a chemotherapy cycle, but should not be given anytime within 24 hours before or after a chemotherapy session.

Possible injection sites are the upper arm, thigh (front of upper legs), buttocks, or stomach (abdomen) excluding a 2” radius around the navel.


Remove syringe tray from carton and allow it to warm up at room temperature for 30 minutes before you prepare to inject yourself.

Open tray by pulling back cover and grab syringe from the tray with your thumb and index finger.

Along with syringe, prepare the following materials that will also be needed for your injection:

  • Alcohol wipe
  • Cotton ball or gauze pad
  • Adhesive bandage
  • Sharps disposal container

Clean administration site.

Hold prefilled syringe by barrel and pull gray needle cap off.

Confirm dosage (full / partial) indicated on syringe matches the dose you have been instructed to take in your prescription.

Point needle up and tap gently until air rises to the top.

Push plunger rod up to the line on the barrel that matches your prescribed dose.

Pinch injection site to create firm surface on the skin.

Hold pinch while inserting needle into skin at 45 to 90 degrees.

Push syringe plunger rod until it reaches bottom.

Pull syringe out and away from skin once injection is complete.

Pull orange safety guard over needle and ensure it audibly clicks into position before disposing in sharps container.


The active ingredient in Neupogen is Filgrastim.


Let your doctor know of any history of kidney dysfunction, sickle cell disorders, latex allergies, or if you are receiving radiation therapy before starting on Neupogen.

Store Neupogen in a refrigerator between 36 and 46 degrees Fahrenheit (2-8 Celsius). Do not freeze.

Women who are pregnant or breastfeeding should not use this medication unless with doctor’s approval.

Use of Neupogen can cause a serious lung problem (ARDS – acute respiratory distress syndrome) or capillary leak syndrome. Be quick to seek medical assistance if you have fever, shortness of breath, stuffy or runny nose followed by tiredness, increased thirst, decreased urination following use of this medication.

Spleen enlargement or a rupturing of the spleen may also be possible with the Neupogen injection, and you should also seek medical assistance if you have left-side upper stomach pain or pain in your left shoulder after an injection.

Keep out of reach of children even while refrigerated.


Negative drug interactions may occur between Neupogen and other Rx medications, including acyclovir, albuterol, lorazepam, diphenhydramine, ciprofloxacin, dexamethasone, hydromorphone, gabapentin, furosemide, leucovorin, levofloxacin, levothyroxine, lorazepam, esomeprazole, omeprazole, ondansetron, oxycodone, pantoprazole, prednisone, prochlorperazine, lenalidomide, trazodone, and ondansetron.

Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Neupogen online.

Side Effects

Neupogen side effects may occur, and some users may experience fever, nosebleeds, cough, bone pain, breathing difficulties, anemia, diarrhea, headache, numbness, rash, or hair loss. If side effects are experienced you may want to stop use and meet with your doctor again to evaluate neutropenia prevention medication alternatives.

Frequently Asked Questions about Neupogen

What is Neupogen used for?

Neupogen helps increase white blood cell counts after chemotherapy or radiation therapy, reducing the risk of infections.

How is Neupogen given?

It's usually injected under the skin or into a vein, either by a healthcare professional or self-administered with proper training.

What are the common side effects?

Bone pain, fever, nausea, fatigue, headache, and injection site reactions are common. Most are mild and temporary.

Who shouldn't take Neupogen?

Individuals with allergies to Neupogen or related medications, pregnant or breastfeeding women, and those with certain health conditions shouldn't take it.

Can I take other medications with Neupogen?

Tell your doctor about all your medications, including supplements, to avoid potential interactions.

Does Neupogen affect fertility?

There's limited data, but men and women using Neupogen should discuss fertility concerns with their doctor.

How long does Neupogen treatment last?

The duration depends on your condition and response to the medication. Your doctor will adjust the dosage and treatment schedule as needed.

How should I store Neupogen?

Store it in the refrigerator, protected from light, and follow your doctor's specific storage instructions.

What should I do if I miss a dose?

Contact your doctor for guidance on missed doses. Don't double up on the next dose without their advice.

Is there any additional information I should know?

Report any severe side effects or allergic reactions to your doctor immediately. Be aware of potential risks like splenic enlargement and increased infection risk during treatment.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.