A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
NEXAVAR is an anticancer medicine used to treat a certain type of kidney cancer called advanced renal cell carcinoma or RCC, and a certain type of liver cancer known as hepatocellular carcinoma or HCC, when it cannot be treated with surgery.
NEXAVAR may cause birth defects or death of an unborn baby. Avoid becoming pregnant while taking NEXAVAR and for at least 2 weeks after stopping your treatment. Men and women should use birth control during and at least 2 weeks after NEXAVAR therapy. Call your doctor right away if you become pregnant. Do not breastfeed while taking NEXAVAR as this medication may be passed through breast milk.
Before starting NEXAVAR, tell your doctor if you have: allergies; heart problems or chest pain; bleeding or bruising problems; high blood pressure; or kidney or liver problems.
NEXAVAR may interact with certain other medicines so tell your doctor about all medicines you take including prescription and over-the-counter (OTC) medicines, vitamins, or herbal supplements. It is especially important to tell your doctor if you take warfarin (Coumadin).
Stop using Nexavar and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;
increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
easy bruising, unusual bleeding;
black, bloody, or tarry stools;
coughing up blood or vomit that looks like coffee grounds;
chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
feeling short of breath, even with mild exertion;
swelling, rapid weight gain;
sudden numbness or weakness, especially on one side of the body; or
confusion, loss of balance or coordination, or seizure (convulsions).
Less serious Nexavar side effects may include:
numbness, tingling, or swelling of your hands or feet;
nausea, vomiting, constipation, diarrhea, stomach pain, loss of appetite;
headache, tired feeling;
pain in your joints, bones, or mouth; cough, trouble breathing; weight loss; hair loss; or dry, itchy skin. Read more: http://www.drugs.com/nexavar.html#ixzz0sVpw0tpN