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Nexletol (bempedoic acid)

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What is Generic?

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


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Nexletol is a cholesterol lowering medication available by prescription that targets LDL cholesterol and is most commonly prescribed for hypercholesterolemia treatment or for heart disease. Bempedoic acid is an ACL-inhibitor drug that works by decreasing the amount of LDL cholesterol produced by the liver. This decreases the risk of heart disease, heart attacks, or strokes resulting from either condition and the prescribing doctor will usually recommend pairing the medication with a lower cholesterol diet and targeted lifestyle changes. Buy Nexletol from Canada and Canpharm and get the lowest Nexletol cost on it.

What is Hypercholesterolemia?

Hypercholesterolemia is a lipid disorder where the individual has greatly elevated low-density lipoprotein (LDL) cholesterol levels that over time result in fat collecting in arteries (atherosclerosis) and increasing the risk of heart attack and stroke. The criterion for having Hypercholesterolemia is to have LDL cholesterol with 190mg/dl or higher without risk factors, higher than 160mg/dl with another risk factor, or above 130mg/dl with two risk factors.

Fact Table
Formula C19H36O5
License US DailyMed, EU EMA
Bioavailability 70%
Legal status Prescription Drugs
Chemical Name Bempedoic acid
Elimination half-life 21±11 hrs
Dosage (Strength) 180mg
Pregnancy Consult Doctor
Brands Nexletol
Protein binding 99.3%
PubChem CID 10472693
MedlinePlus a620020
ChEBI 149601
ATC code C10AX15
DrugBank DB11936
KEGG D10691
Routes of administration By mouth

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Standard dosage is to take Nexletol 180mg orally 1x daily, with or without food. Dosage may vary and you must always take your medication at the strength and frequency indicated in your prescription


The active ingredient in Nexletol is Bempedoic Acid


Tell your doctor if you have any history of liver or kidney disease, gout, or tendon problems before starting on Nexletol.

Older adults may be more susceptible to Nexletol side effects

Women who are pregnant or breastfeeding or plan to become pregnant should not use Nexletol and discuss other cholesterol management approaches with their doctor

Be aware of medication expiry date


Negative drug interactions may occur between Nexletol and other Rx medications, including Zocor, Pravachol, Prednisone, and Ciprofloxacin

Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Nexletol online

Side Effects

Side effects from using Nexletol may occur, and some users may experience muscle spasms, anemia, increased liver enzymes, pain in back, belly, or extremities, or respiratory infections. If side effects are experienced, you may want to stop use and meet with a doctor again to discuss LDL cholesterol medication alternatives.

Frequently Asked Questions about Nexletol

Is Nexletol a Statin?

No, Nexletol is not a statin. Statins can reduce cholesterol production from the liver by targeting the HMG-CoA reductase enzyme, but Bempedoic acid does the same by targeting the MCL enzyme. However, it is quite common to prescribe Nexletol along with a statin drug.

How long does it take for Nexletol to significantly lower LDL cholesterol levels?

The standard timeframe for seeing results from Nexletol is 8 weeks after starting on the medication, and it is at this point that doctors will usually schedule an appointment to measure the patient's LDL cholesterol levels.

How long will I need to be on Nexletol for my cholesterol?

Without diet and lifestyle changes it is very possible for LDL cholesterol levels to return to previous elevated levels, so the amount of time you'll be required to stay on the medication will vary based on the individual and their treatment outcomes.

Are there similar medications that would be alternatives for me if I am at risk with Nexletol because of liver or kidney problems?

Yes, and PCSK9 inhibitor drugs like Praluent (alirocumab) and Repatha (evolcocumab) are potential alternatives to Nexletol for people with high LDL cholesterol but at risk because of a weakened liver or kidneys

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.