Nexlizet (Bempedoic acid and Ezetimibe)

NEXLIZET is a prescription medicine that contains 2 cholesterol-lowering medicines, bempedoic acid and ezetimibe. It is used, along with diet and other lipid-lowering medicines, in the treatment of adults who need additional lowering of “bad” cholesterol (LDL-C) and have: heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C, and/or known cardiovascular disease due to high levels of bad cholesterol It is not known if NEXLIZET can decrease problems related to high cholesterol, such as heart attacks or stroke.

Cautions

Do not take NEXLIZET if you are allergic to ezetimibe tablets. Ezetimibe, one of the ingredients in NEXLIZET, can cause serious allergic reactions. Stop taking NEXLIZET and call your doctor, or go to the nearest emergency room, if you have the following: swelling of your face, lips, mouth, or tongue wheezing or trouble breathing severe itching and/or skin rashes, redness, or swelling dizziness or fainting fast heartbeat or pounding in your chest NEXLIZET can cause side effects that can become serious, including: high levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms: severe foot pain, especially in the toe joint warm joints swelling tender joints joint redness tendon problems: Stop taking NEXLIZET immediately and get medical help right away if you get any of the following signs or symptoms of tendon rupture: hear or feel a snap or pop in a tendon area bruising right after an injury in a tendon area unable to move the affected area or put weight on the affected area

Side Effects

Tell your doctor right away about any side effect you experience. NEXLIZET can cause side effects, including: symptoms of the common cold or flu muscle spasms back pain stomach pain bronchitis pain in the shoulders, legs, or arms diarrhea fatigue